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Transcriptomic characterization of mucosal hemocytes in the eastern oyster (<i>Crassostrea virginica</i>) underlines their potential role as immune sentinels. [PDF]

Front Immunol
Abdallah S, Grouzdev D, Pales Espinosa E, Allam B.   +3 more
europepmc   +1 more source

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Novel Functions of Endothelial Scavenger Receptor Class B Type I

Current Atherosclerosis Reports, 2021
Scavenger receptor class B type I (SR-BI) serves a key role in the reverse cholesterol transport in the liver as the high-affinity receptor for HDL. SR-BI is abundantly expressed in endothelium, and earlier works indicate that the receptor mediates anti-atherogenic actions of HDL. However, more recent studies uncovered novel functions of endothelial SR-
Liming Yu, Yao Dai, Chieko Mineo
openaire   +2 more sources

Class B Scavenger Receptors, Caveolae and Cholesterol Homeostasis

Trends in Cardiovascular Medicine, 1999
Class B scavenger receptors are predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. Caveolae and their associated protein, caveolin, have been implicated in cholesterol trafficking and in the regulation of cellular cholesterol homeostasis. Recent studies indicate that scavenger receptor,
G A, Graf, S V, Matveev, E J, Smart
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Role of CD36, the Macrophage Class B Scavenger Receptor, in Atherosclerosis

Annals of the New York Academy of Sciences, 2001
Abstract: Recent work in the field of atherosclerosis has greatly expanded our knowledge of the pathogenesis of this disease. Scavenger receptors, including CD36, are thought to be most important early in the disease progression during macrophage uptake of modified LDL and foam cell formation.
A C, Nicholson, J, Han, M, Febbraio, R L, Silversterin, D P, Hajjar   +4 more
openaire   +2 more sources

The cellular biology of scavenger receptor class B type I

Current Opinion in Lipidology, 2001
The HDL receptor scavenger receptor class B type I plays an important role in meditating the uptake of HDL-derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. However, the mechanism by which scavenger receptor class B type I mediates selective cholesterol uptake is unclear.
D L, Silver, A R, Tall
openaire   +2 more sources

Scavenger receptor class B type I and immune dysfunctions

Current Opinion in Endocrinology, Diabetes & Obesity, 2014
To summarize the recent findings about the roles of scavenger receptor class B type I (SR-BI) in immunity and discuss the underlying mechanisms by which SR-BI prevents immune dysfunctions.SR-BI is well known as a high-density lipoprotein (HDL) receptor playing key roles in HDL metabolism and in protection against atherosclerosis.
Zhong, Zheng, Junting, Ai, Xiang-An, Li
openaire   +2 more sources

Functions of scavenger receptor class B, type I in atherosclerosis

Current Opinion in Lipidology, 2012
This review highlights the diverse roles of the high-affinity HDL receptor scavenger receptor class B, type I (SR-BI) in the modulation of global cholesterol homeostasis and vascular cell function, and the potential implications of these processes in atherosclerosis.SR-BI in the liver plays a critical role in reverse cholesterol transport and it ...
Chieko, Mineo, Philip W, Shaul
openaire   +2 more sources