Results 271 to 280 of about 15,256,107 (329)
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Role of CD36, the Macrophage Class B Scavenger Receptor, in Atherosclerosis
Annals of the New York Academy of Sciences, 2001Abstract: Recent work in the field of atherosclerosis has greatly expanded our knowledge of the pathogenesis of this disease. Scavenger receptors, including CD36, are thought to be most important early in the disease progression during macrophage uptake of modified LDL and foam cell formation.
A C, Nicholson +4 more
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Scavenger receptor class B type I and immune dysfunctions
Current Opinion in Endocrinology, Diabetes & Obesity, 2014To summarize the recent findings about the roles of scavenger receptor class B type I (SR-BI) in immunity and discuss the underlying mechanisms by which SR-BI prevents immune dysfunctions.SR-BI is well known as a high-density lipoprotein (HDL) receptor playing key roles in HDL metabolism and in protection against atherosclerosis.
Zhong, Zheng, Junting, Ai, Xiang-An, Li
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Characterisation of scavenger receptor class B type 1 in rare minnow (Gobiocypris rarus)
Fish and Shellfish Immunology, 2019Scavenger receptor class B type 1 (SRB1) is a transmembrane protein belonging to the scavenger receptors (SRs) family and it plays an important role in viral entry. Not much is known on SRB1 in teleost fish. Grass carp reovirus (GCRV) cause huge economic
Mi Ou +5 more
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CD36 in Atherosclerosis: The Role of a Class B Macrophage Scavenger Receptor
Annals of the New York Academy of Sciences, 2000Abstract: CD36, an 88 kD transmembrane glycoprotein, is an important receptor for oxidized lipoproteins. Unlike the LDL receptor, expression of CD36 is upregulated by this pro‐atherogenic particle, and binding and uptake perpetuates a cycle of lipid accumulation and receptor expression.
A C, Nicholson +4 more
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Fish and Shellfish Immunology, 2019
In the present study, a scavenger receptor class B type I (designed as RpSR‐BI) was cloned and characterized from manila clam Ruditapes philippinarum.
Ding-Long Yang +6 more
semanticscholar +1 more source
In the present study, a scavenger receptor class B type I (designed as RpSR‐BI) was cloned and characterized from manila clam Ruditapes philippinarum.
Ding-Long Yang +6 more
semanticscholar +1 more source
Functions of scavenger receptor class B, type I in atherosclerosis
Current Opinion in Lipidology, 2012This review highlights the diverse roles of the high-affinity HDL receptor scavenger receptor class B, type I (SR-BI) in the modulation of global cholesterol homeostasis and vascular cell function, and the potential implications of these processes in atherosclerosis.SR-BI in the liver plays a critical role in reverse cholesterol transport and it ...
Chieko, Mineo, Philip W, Shaul
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HDL and Scavenger Receptor Class B Type I (SRBI)
2022The scavenger receptor class B type I (SR-BI) is a versatile HDL receptor protein. It is highly expressed in liver and steroidogenic tissues. SR-BI regulates selective uptake of cholesterol ester (CE) from HDL, revealing its role in mediating reverse cholesterol transport (RCT) and steroid hormone synthesis.
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HDL scavenger receptor class B type I and platelet function
Current Opinion in Lipidology, 2011HDL cholesterol levels have been inversely correlated with thrombosis and HDL has been shown to mediate various antithrombotic effects. However, molecular mechanisms underlying the suppressing effect of HDL on platelet reactivity are not completely understood.
Jerzy-Roch, Nofer, Miranda, van Eck
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Scavenger Receptor Class B, Type I: A Promising Immunotherapy Target
Immunotherapy, 2011Scavenger receptor class B, type I (SR-BI) is a crucial molecule in lipid metabolism, since the interaction of high-density lipoproteins (HDLs) with SR-BI is involved in reverse cholesterol transport and cholesterol efflux. Recent findings also underscore a critical role of SR-BI in antimicrobial and immune responses. SR-BI is not only highly expressed
Jessica, Fioravanti +2 more
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Characterization of scavenger receptor class B
2009Besides its housekeeping functions in all mammalian cells, cholesterol contributes to different biological functions like bile acid-, vitamin D- or steroid hormone synthesis. Thus, multiple pathways have evolved to ensure full supply of animal cells with cholesterol, involving different lipoproteins and cell surface receptors.
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