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Developmental expression and immune role of the class B scavenger receptor cd36 in zebrafish
Developmental & Comparative Immunology, 2016CD36 is a transmembrane glycoprotein belonging to the scavenger receptor class B family which plays crucial roles in innate immunity. Although CD36 is widely documented in mammals, the study of its functions in fish is still limited. Here we report the identification of a zebrafish cd36 homologue.
Kai Liu +7 more
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Activation of the rat scavenger receptor class B type I gene by PPARα
Molecular and Cellular Endocrinology, 2006Peroxisomal proliferator activated receptor alpha (PPARalpha) is activated by fibrate drugs which are known to protect against atherosclerosis. The present study examines the effects of PPARalpha on SR-BI expression. For this study, a rat SR-BI promoter-luciferase reporter gene construct was co-transfected into different cell lines with expression ...
Dayami, Lopez, Mark P, McLean
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Hyperglycemia suppresses hepatic scavenger receptor class B type I expression
American Journal of Physiology-Endocrinology and Metabolism, 2008Hyperglycemia is a major risk factor for atherosclerotic disease. Hepatic scavenger receptor class B type I (SR-BI) binds HDL particles that mediate reverse cholesterol transport and thus lowers the risk of atherosclerosis. Here we examined glucose regulation of SR-BI gene expression in both HepG2 cells and whole animals. Results showed that hepatic SR-
Koji, Murao +8 more
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Scavenger receptor class B type I polymorphisms and peripheral arterial disease
Metabolism, 2007Genetic variations of the scavenger receptor class B type I (SR-BI) have been demonstrated to be associated with plasma lipid parameters, anthropomorphic parameters, and coronary artery disease. We determined the frequency of 3 single-nucleotide polymorphisms within the SR-BI gene (SCARB1) in 354 patients with peripheral arterial disease (PAD) and 354 ...
Andreas, Ritsch +13 more
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Expression of scavenger receptor class B type I in gallbladder columnar epithelium
Journal of Gastroenterology and Hepatology, 2002AbstractBackgroundThe lipid content of bile may be modified by the gallbladder epithelium. Recent studies indicate that cholesterol can be absorbed from bile and that this can be enhanced by apolipoprotein (apo) A‐I. SR‐BI is a multifunctional receptor capable of binding a wide array of native or modified lipoproteins, phospholipid or bile acid ...
Magnus S C, Johnson +5 more
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Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression
Neurochemical ResearchScavenger receptor class B type I (SR-BI) is abundant in adult mouse and human brains, but its function in the central nervous system (CNS) remains unclear. This study explored the role of SR-BI in epilepsy and its possible underlying mechanism. Expression patterns of SR-BI in the brains of mice with kainic acid (KA)-induced epilepsy were detected ...
Yunyi, Huang +4 more
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CD36, the Macrophage Class B Scavenger Receptor
2001Andrew C. Nicholson +6 more
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Lipoprotein binding to the class B scavenger receptor CD36
Gastroenterology, 2000Willem J. de Villiers +5 more
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