Results 261 to 270 of about 24,292 (301)

CD36 in Atherosclerosis: The Role of a Class B Macrophage Scavenger Receptor

Annals of the New York Academy of Sciences, 2000
Abstract: CD36, an 88 kD transmembrane glycoprotein, is an important receptor for oxidized lipoproteins. Unlike the LDL receptor, expression of CD36 is upregulated by this pro‐atherogenic particle, and binding and uptake perpetuates a cycle of lipid accumulation and receptor expression.
A C, Nicholson, M, Febbraio, J, Han, R L, Silverstein, D P, Hajjar   +4 more
openaire   +2 more sources

HDL and Scavenger Receptor Class B Type I (SRBI)

2022
The scavenger receptor class B type I (SR-BI) is a versatile HDL receptor protein. It is highly expressed in liver and steroidogenic tissues. SR-BI regulates selective uptake of cholesterol ester (CE) from HDL, revealing its role in mediating reverse cholesterol transport (RCT) and steroid hormone synthesis.
openaire   +2 more sources

Scavenger receptor class B type I (SR-BI) in Ruditapes philippinarum: A versatile receptor with multiple functions

Fish and Shellfish Immunology, 2019
In the present study, a scavenger receptor class B type I (designed as RpSR-BI) was cloned and characterized from manila clam Ruditapes philippinarum.
Dinglong Yang, Yijing Han, Lizhu Chen
exaly   +2 more sources

HDL scavenger receptor class B type I and platelet function

Current Opinion in Lipidology, 2011
HDL cholesterol levels have been inversely correlated with thrombosis and HDL has been shown to mediate various antithrombotic effects. However, molecular mechanisms underlying the suppressing effect of HDL on platelet reactivity are not completely understood.
Jerzy-Roch, Nofer, Miranda, van Eck
openaire   +2 more sources

Uptake and fate of class B scavenger receptor ligands in HepG2 cells

European Journal of Biochemistry, 1999
Class B scavenger receptors (SR‐Bs) interact with native, acetylated and oxidized low‐density lipoprotein (LDL, AcLDL and OxLDL), high‐density lipoprotein (HDL3) and maleylated BSA (M‐BSA). The aim of this study was to analyze the catabolism of CD36‐ and LIMPII‐analogous‐1 (CLA‐1), the human orthologue for the scavenger receptor class B type I (SR‐BI),
D, Rhainds, L, Falstrault, C, Tremblay, L, Brissette   +3 more
openaire   +2 more sources

Scavenger Receptor Class B, Type I: A Promising Immunotherapy Target

Immunotherapy, 2011
Scavenger receptor class B, type I (SR-BI) is a crucial molecule in lipid metabolism, since the interaction of high-density lipoproteins (HDLs) with SR-BI is involved in reverse cholesterol transport and cholesterol efflux. Recent findings also underscore a critical role of SR-BI in antimicrobial and immune responses. SR-BI is not only highly expressed
Jessica, Fioravanti, José, Medina-Echeverz, Pedro, Berraondo   +2 more
openaire   +2 more sources

Interaction of scavenger receptor class B type I with peroxisomal targeting receptor Pex5p

Biochemical and Biophysical Research Communications, 2003
Scavenger receptor class B type I (SR-BI) is an HDL receptor that mediates selective HDL lipid uptake. Peroxisomes play an important role in lipid metabolism and peroxisomal targeting signal type 1 (PTS1)-containing proteins are translocated to peroxisomes by the peroxisomal targeting import receptor, Pex5p.
Magnus S C, Johnson, Jenny M, Johansson, Per Arne, Svensson, Maria A I, Aberg, Peter S, Eriksson, Lena M S, Carlsson, Björn, Carlsson   +6 more
openaire   +2 more sources

Scavenger Receptor Classes A and B: Their Roles in Atherogenesis and the Metabolism of Modified LDL and HDL

Annals of the New York Academy of Sciences, 2000
Abstract: Scavenger‐receptor class A has been held responsible for the clearance of modified LDL from the blood circulation. However, in mice deficient in scavenger‐receptor class A, the decay in vivo of acetylated LDL (t1/2 < 2 min), as well as tissue distribution and liver uptake (at 5 min 77.4 ±6 4.6% of the injected dose) are not significantly ...
van Berkel, T. J., van Eck, M., Herijgers, N., Fluiter, K., Nion, S.   +4 more
openaire   +3 more sources

Characterization of scavenger receptor class B

2009
Besides its housekeeping functions in all mammalian cells, cholesterol contributes to different biological functions like bile acid-, vitamin D- or steroid hormone synthesis. Thus, multiple pathways have evolved to ensure full supply of animal cells with cholesterol, involving different lipoproteins and cell surface receptors.
openaire   +1 more source

Scavenger receptor class B type 1 gene polymorphisms and female fertility

Current Opinion in Endocrinology, Diabetes & Obesity, 2012
Multiple studies have demonstrated a role for scavenger receptor class B type 1 (SR-B1) in female fertility. Recent studies have implicated specific SR-B1 gene polymorphisms in decreased progesterone production and suboptimal fertility outcomes.The lipoprotein receptor SR-B1 has been known to mediate selective uptake of lipids into steroidogenic ...
Mindy S, Christianson, Melissa, Yates
openaire   +2 more sources