Results 21 to 30 of about 59,530 (304)

The distinct features of microbial 'dysbiosis' of Crohn's disease do not occur to the same extent in their unaffected, genetically linked kindred [PDF]

, 2017
Background/Aims: Studying the gut microbiota in unaffected relatives of people with Crohn’s disease (CD) may advance our understanding of the role of bacteria in disease aetiology. Methods: Faecal microbiota composition (16S rRNA gene sequencing),
Bertz, Martin, Calus, Szymon T., Edwards, Christine A., Gaya, Daniel R., Gerasimidis, Konstantinos, Hansen, Richard, Hanske, Laura, Ijaz, Umer Zeeshan, Loman, Nick, McGrogan, Paraic, Quince, Christopher, Russell, Richard K.   +11 more
core   +10 more sources

Gut microbiota-derived short chain fatty acids are potential mediators in gut inflammation

Animal Nutrition, 2022
Gut inflammation is a challenging concern in humans and animals, which disturbs normal growth and leads to severe bowel diseases. Short chain fatty acids (SCFA) are the gut microbiota metabolites produced from fermentation of non-digestible carbohydrates,
Muhammad Akhtar, Yan Chen, Ziyu Ma, Xiaolong Zhang, Deshi Shi, Jawaria A. Khan, Huazhen Liu   +6 more
doaj   +1 more source

Mixed Spices at Culinary Doses Have Prebiotic Effects in Healthy Adults: A Pilot Study. [PDF]

, 2019
Spices were used as food preservatives prior to the advent of refrigeration, suggesting the possibility of effects on microbiota. Previous studies have shown prebiotic activities in animals and in vitro, but there has not been a demonstration of ...
Carpenter, Catherine L, Gilbuena, Irene, Heber, David, Henning, Susanne M, Huang, Jianjun, Lee, Ru-Po, Li, Zhaoping, Lu, Qing-Yi, Rasmussen, Anna M, Shao, Paul, Thames, Gail, Yang, Jieping   +11 more
core   +1 more source

SCFAs strongly stimulate PYY production in human enteroendocrine cells [PDF]

Scientific Reports, 2018
AbstractPeptide-YY (PYY) and Glucagon-Like Peptide-1 (GLP-1) play important roles in the regulation of food intake and insulin secretion, and are of translational interest in the field of obesity and diabetes. PYY production is highest in enteroendocrine cells located in the distal intestine, mirroring the sites where high concentrations of short chain
Larraufie, Pierre, Martin-Gallausiaux, Camille, Lapaque, Nicolas, Dore, Joel, Gribble, F. M., Reimann, F., Blottiere, Herve   +6 more
openaire   +4 more sources

Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice [PDF]

, 2010
Although most of the proposed beneficial effects of fiber consumption have been attributed to viscous and gel-forming properties of soluble fiber, it is mainly insoluble cereal fiber and whole grains that are strongly associated with reduced diabetes ...
Andreas F.H. Pfeiffer, Backhed, Cameron-Smith, Covington, de Munter, Frank Isken, Galisteo, Hong, Howarth, Isken, Jenkins, Jenkins, King, Kumar, Liese, Martin O. Weickert, Martin Osterhoff, McNeil, Owusu-Asiedu, Pereira, Pittler, Ristow, Robertson, Robertson, Schulze, Song, Steneberg, Stewart, Susanne Klaus, Thorburn, Track, Weickert, Weickert, Weickert, Weickert, Wolfrum, Wolfrum   +36 more
core   +1 more source

The intestinal microbiota and metabolites in patients with anorexia nervosa

Gut Microbes, 2021
Brain-gut microbiota interactions are intensively studied in connection with various neurological and psychiatric diseases. While anorexia nervosa (AN) pathophysiology is not entirely clear, it is presumably linked to microbiome dysbiosis.
Petra Prochazkova, Radka Roubalova, Jiri Dvorak, Jakub Kreisinger, Martin Hill, Helena Tlaskalova-Hogenova, Petra Tomasova, Helena Pelantova, Martina Cermakova, Marek Kuzma, Josef Bulant, Martin Bilej, Kvido Smitka, Alena Lambertova, Petra Holanova, Hana Papezova   +15 more
doaj   +1 more source

The therapeutic potential of short-chain fatty acids enemas in inflammatory bowel diseases: a systematic review [PDF]

Farmacja Polska, 2020
It has been suggested that short-chain fatty acid (SCFA) enemas might improve clinical, endoscopic and histological scores in patients with inflammatory bowel disease.
Nina Kaczmarek, Marta Kokot, Aleksandra Makarewicz, Aleksandra Glapa-Nowak, Jan Krzysztof Nowak, Małgorzata Jamka, Jarosław Walkowiak   +6 more
doaj   +1 more source

Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats [PDF]

, 2014
We thank Donna Wallace and the Rowett Animal House staff for the daily care of experimental rats, body weight and food intake measurements and MRI scanning, Vivien Buchan and Donna Henderson of the Rowett Analytical Department for proximate analyses and ...
Adam, Clare L, Dalby, Matthew J, Garden, Karen, Gratz, Silvia W., Richardson, Anthony J, Ross, Alexander W, Thomson, Lynn M, Williams, Patricia A   +7 more
core   +2 more sources

Low-Dose Interleukin-2 Altered Gut Microbiota and Ameliorated Collagen-Induced Arthritis

Journal of Inflammation Research, 2022
Na Li,1 Xuefei Li,1 Rui Su,1 Ruihe Wu,1 Hong-Qing Niu,1 Jing Luo,1 Chong Gao,2 Xiaofeng Li,1 Caihong Wang1 1Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People’s Republic of China; 2Pathology, Joint ...
Li N, Li X, Su R, Wu R, Niu HQ, Luo J, Gao C, Li X, Wang C   +8 more
doaj  

Fecal microbiota composition associates with the capacity of human peripheral blood monocytes to differentiate into immunogenic dendritic cells in vitro

Gut Microbes, 2021
Although promising for active immunization in cancer patients, dendritic cells (DCs) vaccines generated in vitro display high inter-individual variability in their immunogenicity, which mostly limits their therapeutic efficacy. Gut microbiota composition
Dušan Radojević, Sergej Tomić, Dušan Mihajlović, Maja Tolinački, Bojan Pavlović, Dragana Vučević, Svetlana Bojić, Nataša Golić, Miodrag Čolić, Jelena Đokić   +9 more
doaj   +1 more source