Results 81 to 90 of about 48,227 (244)

Yixiao Formula Suppresses Myocardial Fibrosis Through UpregulatingmiR‐133a and Downregulating TGF‐β/Smads Signal Molecules

Journal of Diabetes Research, Volume 2026, Issue 1, 2026.
Background Yixiao formula (YXF), a traditional Chinese herbal medicine, has demonstrated clinical efficacy in alleviating symptoms of diabetic cardiomyopathy (DCM). The therapeutic mechanism underlying YXF′s effects on DCM remains poorly understood. Myocardial fibrosis is a key pathogenic mechanism in DCM, and previous studies have indicated that miR ...
Qiyao Zhao, Yalu Wen, Honghui Wu, Jiaoyue Li, Yunpeng Luo, Ping Li, Ye Zhang, Chaoyue Hu, Jukai Huang, Li Zhang, Xiaohui Yang, Huantian Cui   +11 more
wiley   +1 more source

Chinese Herbal Medicines for Diabetic Cardio‐Cerebrovascular Diseases: Key Bioactive Metabolites and Action Mechanisms

Journal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Currently, the global incidence of diabetes is increasing, particularly in populous developing regions. In China, over 290 million people are affected by diabetic cardio‐cerebrovascular diseases. These diseases account for more than 40% of deaths and impose a significant economic burden on both society and families.
Ying Su, Shuwen Luo, Wei Li, Cuicui Cheng, Wei Liu, Xinyu Yang, Zhen Xing, Eric Gumpricht   +7 more
wiley   +1 more source

Analysis of Effect of Schisandra in the Treatment of Myocardial Infarction Based on Three-Mode Gene Ontology Network

Frontiers in Pharmacology, 2019
Schisandra chinensis is a commonly used traditional Chinese medicine, which has been widely used in the treatment of acute myocardial infarction in China.
Siyao Hu, Huali Zuo, Jin Qi, Yuanjia Hu, Boyang Yu   +4 more
doaj   +1 more source

Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
This study elucidates the central role of transient receptor potential (TRP) channels in driving neuroinflammation across neurological disorders. Acting as critical molecular sensors on neurons and glial cells, TRP channels' activation initiates downstream pathways that promote the release of proinflammatory cytokines, a pathological mechanism in ...
Daji Guo, Mengjiao Cai, Yanmin Xian, Yinyin Chen, Yujun Feng, Chun Hu, Lizhang Zeng, Lei Shi, Shiqing Zhang   +8 more
wiley   +1 more source

T-Cadinol Nerolidol Ether from

Natural Product Communications, 2008
From the ethanol extract of the cauloms of Schisandra chinensis , a novel T-cadinol nerolidol ether has been isolated. Its structure was determined from mass spectrometric and NMR spectroscopic data.
Asmita V. Patel, Gerald Blunden, Peter D. Cary, Lubomír Opletal, Markéta Beránkova, Kersti Karu, David E. Thurston, Milan Pour   +7 more
doaj   +1 more source

Schisandrae Fructus ethanol extract ameliorates inflammatory responses and articular cartilage damage in monosodium iodoacetate-induced osteoarthritis in rats [PDF]

Schisandrae Fructus, the fruit of Schisandra chinensis (Turcz.) Baill., is widely used in traditional medicine for the treatment of a number of chronic diseases.
Choi, Eun Ok, Choi, Il-Whan, Choi, Young Whan, Choi, Yung Hyun, Hong, Su Hyun, Jeong, Jin-Woo, Kim, Bum Hoi, Kim, Gi-Young, Kim, Jongsik, Kim, Ki Young, Kim, Sung Goo, Kong, Gyu Min, Kwon, Da Hye, Lee, Ki Won, Park, Cheol   +14 more
core   +1 more source

Effect directed analysis and TLC screening of Schisandra chinensis fruits

Journal of Chromatography A, 2020
The fruit of Schisandra chinensis (Chinese magnolia vine), the medicinal plant well-known in Traditional Chinese Medicine, gains great popularity in the modern phytopharmacology. This phenomena is related to the wide and powerful healing properties, including supporting immune, nervous and digestive systems activity. S.
Ewelina Sobstyl, Agnieszka Szopa, Halina Ekiert, Sebastian Gnat, Rafał Typek, Irena Maria Choma   +5 more
openaire   +4 more sources

Alcohol‐Related Liver Disease and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 6, Issue 12, December 2025.
Alcohol‐related (ALD) and metabolic dysfunction‐associated (MASLD) steatotic liver disease, while initiated by distinct etiologies (ethanol vs. metabolic stress), converge on shared core pathogenic pathways that drive progression. These include dysregulated lipid metabolism, programmed cell death, cellular senescence, gut dysbiosis, and immune ...
Yupin Tan, Yirui Hu, Ye Yang, Huikuan Chu   +3 more
wiley   +1 more source

HPLC-MS analysis of Schisandra lignans and their metabolites in Caco-2 cell monolayer and rat everted gut sac models and in rat plasma

Acta Pharmaceutica Sinica B, 2011
The absorption profiles of Schisandra chinensis were evaluated using the human Caco-2 cell monolayer and rat everted gut sac models, as well as in rat plasma.
Jia-ming Yang, Siu-po P. IP, Hok-keung J. Yeung, Chun-tao Che   +3 more
doaj   +1 more source

Genomic imprinting in an early‐diverging angiosperm reveals an ancient mechanism for seed initiation in flowering plants

New Phytologist, Volume 249, Issue 4, Page 1580-1591, February 2026.
Ana M. Florez‐Rueda, Mathias Scharmann, Leonardo P. de Souza, Alisdair R. Fernie, Julien B. Bachelier, Duarte D. Figueiredo   +5 more
wiley   +1 more source