Results 91 to 100 of about 12,357,672 (189)
Inhibitory effect of schisandrin B on gastric cancer cells in vitro
To investigate the inhibitory effect and possible mechanism of action of schisandrin B in SC-B on gastric cancer cells in vitro.SC-B consisted of schisandrin B, aloe-emodin, and Astragalus polysaccharides. Exponentially growing human gastric cancer SGC-7901 cells were divided into six treatment groups: (1) control group (RPMI 1640 medium); (2) negative
Xiao-Ni, Liu +5 more
openaire +2 more sources
To investigate the involvement of reactive oxidant species (ROS), presumably arising from cytochrome P-450 (CYP)-catalyzed metabolism of schisandrin B (Sch B), in triggering glutathione antioxidant response, Sch Binduced reduced nicotinamide adenine ...
Chen, Na, Ko, Kam Ming
core +1 more source
The purpose of this study is to determine the efficacy and molecular mechanism of the effect of schisandrin b (SCHB) on treating erectile dysfunction (ED) in a rat model with bilateral cavernous crushing nerve injury.The ED rat model was established with bilateral cavernous nerve crushing, and then confirmed by apomorphine. Fifty healthy eight-week-old
LIU, WEI +4 more
openaire +3 more sources
Beneficial effect of (-)Schisandrin B against 3-nitropropionic acid-induced cell death in PC12 cells
Huntington's disease (HD) is characterized by the dysfunction of mitochondrial energy metabolism, which is associated with the functional impairment of succinate dehydrogenase (mitochondrial complex II), and pyruvate dehydrogenase (PDH). Treatment with 3-
Lam, Philip Y., Ko, Kam Ming
core +1 more source
Mingfeng Shao,1 Wenfang Yang,2 Guangying Han1 1Department of Cardiology, Linyi People’s Hospital, Linyi, Shandong, People’s Republic of China; 2Department of Internal Medicine, Linyi Hot Spring Hospital of Shandong Coal ...
Shao M, Yang W, Han G
doaj
Acquired drug resistance poses a great challenge in cancer therapy. Drug efflux and anti-apoptotic processes are the most two common mechanisms that confer cancer drug resistance.
Shengpeng Wang +5 more
doaj +1 more source
As a preliminary investigation to exploring whether the methylenedioxy group and the cyclooctadiene ring of the dibenzo[a,c]cyclooctadiene (schisandrin) molecule plays an important role in the protection against myocardial ischemia-reperfusion (IR ...
Ko, Kam Ming, Yim, Tze Kin
core +1 more source
Exploring the Influence of Schisandrin B on Mice with Multiple Myeloma
Background/Aims: The management of multiple myeloma (MM), a formidable hematological malignancy, continues to pose substantial challenges in the medical realm. Schisandrin B (Sch B), a compound derived from Traditional Chinese Medicine, has demonstrated potent anti-tumorigenic properties, providing a promising avenue for therapeutic intervention in ...
Anna Li +7 more
openaire +1 more source
Schisandrin B (Sch B), the most abundant and biologically active dibenzocyclooctadiene lignan present in Fructus Schisandrae (FS), is usually prepared and supplied in the form of a mixture of its stereoisomers, namely (±)γ-schisandrin and (–)Sch B ...
Luk, Ka Fai
core
Schisandrin B from Schisandra chinensis reduces hepatic lipid contents in hypercholesterolaemic mice
The effects of schisandrin B (Sch B) on liver and serum lipid contents were investigated in mice with experimentally-induced hypercholesterolaemia. Hypercholesterolaemia was induced either by oral administration of a cholesterol/bile salts mixture (2/0 ...
Fang, Hai-Yan +14 more
core +1 more source

