Results 71 to 80 of about 1,905 (169)

(−)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells

, 2011
Exposure to paraquat (PQ; N,N'-dimethyl-4-4'-bipyridium), a potent herbicide, can lead to neuronal cell death and increased risk of Parkinson's disease because of oxidative stress.
Philip Y. Lam, Kam Ming Ko, Lam, Philip Y., Ko, Kam Ming   +3 more
core   +1 more source

A Novel Mouse Model of Combined Hyperlipidemia Associated With Steatosis and Liver Injury by a Single-Dose Intragastric Administration of Schisandrin B/Cholesterol/Bile Salts Mixture

, 2013
Hyperlipidemia is referred to as hypercholesterolemia, hypertriglyceridemia, or both in combined hyperlipidemia. Here, a novel mouse model of combined hyperlipidemia is described.
Yu, Qing, Pan, Si Yuan, Zhan-Hong Jia, Zhu, Pei Li, Qing Yu, Ko, Kam Ming, Jia, Zhan Hong, Yi Zhang, Zhang, Yi, Nan Sun, Si-Yuan Pan, Kam-Ming Ko, Wang, Xiao Yan, Sun, Nan, Yu, Zhi Ling, Pei-Li Zhu, Zhi-Ling Yu, Xiao-Yan Wang   +17 more
core   +1 more source

Borneol-Modified Schisandrin B Micelles Cross the Blood–Brain Barrier To Treat Alzheimer’s Disease in Aged Mice

Objective: Schisandrin B (Sch B) is a bioactive dibenzocyclooctadiene derizative that is prevalent in the fruit of Schisandra chinensis. Numerous studies have demonstrated that Sch B has a neuroprotective action by reducing oxidative stress and ...
Mo Liu (10658546), Feng-rui Li (17780783), Yu-meng Du (17780786), Zi-xu Zhang (17780795), Liang Kong (154890), Yang Yu (4292), Xue-tao Li (8855204), Yang Liu (4829), Jia-hua Wang (17780789), Mu-han Chen (17780792), Rui-jun Ju (8855201)   +10 more
core   +1 more source

Differential effect of schisandrin B and dimethyl diphenyl bicarboxylate (DDB) on hepatic mitochondrial glutathione redox status in carbon tetrachloride intoxicated mice

, 2000
The effects of schisandrin B (Sch B), a dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis, and dimethyl diphenyl bicarboxylate (DDB), a synthetic intermediate of schisandrin C (also a dibenzocyclooctadiene derivative), on ...
Ip, Siu Po, Ko, Kam Ming, Yiu, Ho Yan
core   +1 more source

Protective effects on myocardial infarction model: delivery of schisandrin B using matrix metalloproteinase-sensitive peptide-modified, PEGylated lipid nanoparticles

, 2017
Mingfeng Shao,1 Wenfang Yang,2 Guangying Han1 1Department of Cardiology, Linyi People’s Hospital, Linyi, Shandong, People’s Republic of China; 2Department of Internal Medicine, Linyi Hot Spring Hospital of Shandong Coal ...
Yang W, Wenfang Yang, Han G, Shao M, Guangying Han, Mingfeng Shao   +5 more
core   +1 more source

Prevention of scopolamine-induced memory deficits by schisandrin B, an antioxidant lignan fromSchisandra chinensisin mice

, 2011
The preventive effect of schisandrin B (Sch B), an antioxidant ingredient of Schisandra chinensis, was studied on scopolamine-induced dementia in mouse. Scopolamine developed oxidative stress in the brain with the decreased levels of antioxidant enzymes ...
Konishi, Tetsuya, Kam Ming Ko, Giridharan, Vijayasree V., Rajarajan A. Thandavarayan, Thandavarayan, Rajarajan A., Ko, Kam Ming, Shinji Sato, Tetsuya Konishi, Sato, Shinji, Vijayasree V. Giridharan   +9 more
core   +1 more source

Antioxidant effect of schisandrin B in nervous tissue

, 2001
Fructus schisandrae (FS), the fruit of Schisandra chinensis, has been used as tonic and sedative in traditional Chinese medicine. Previous studies from our laboratory have demonstrated that schisandrin B (Sch B), a dibenzocyclooctadiene derivative ...
Lam, Brian Yee-Hong
core  

Schisandrin B alleviates acute oxidative stress via modulation of the Nrf2/Keap1-mediated antioxidant pathway

, 2019
Schisandrin B (Sch B), one of the main effective components of the dried fruit of Schisandra chinensis, protects neurons from oxidative stress in the central nervous system.
Ying Wu, Mei Tang, Mai Li, Li-qing Yao, Zheng-cai Li   +4 more
core   +1 more source

Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy. [PDF]

Pharm Biol, 2023
Ma M, Wei N, Yang J, Ding T, Song A, Chen L, Zheng S, Jin H.   +7 more
europepmc   +1 more source

Schisandrin B inhibits tumor progression of hepatocellular carcinoma by targeting the RhoA/ROCK1 pathway. [PDF]

J Gastrointest Oncol, 2023
Yang H, Wu T.
europepmc   +1 more source