Results 61 to 70 of about 1,905 (169)

Schisandrin B attenuates CCl4-induced liver fibrosis in rats by regulation of Nrf2-ARE and TGF-β/Smad signaling pathways

, 2017
Qingshan Chen,1,* Hai Zhang,2,* Yan Cao,3 Ying Li,1 Sen Sun,1 Junping Zhang,4 Guoqing Zhang1 1Department of Pharmacy, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China, 2Department of Pharmacy, Shanghai ...
Li Y, Zhang H, Cao Y, Sun S, Zhang GQ, Chen QS, Zhang JP   +6 more
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Beneficial effect of (-)Schisandrin B against 3-nitropropionic acid-induced cell death in PC12 cells

, 2012
Huntington's disease (HD) is characterized by the dysfunction of mitochondrial energy metabolism, which is associated with the functional impairment of succinate dehydrogenase (mitochondrial complex II), and pyruvate dehydrogenase (PDH). Treatment with 3-
Lam, Philip Y., Ko, Kam Ming
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Methylenedioxy group and cyclooctadiene ring as structural determinants of schisandrin in protecting against myocardial ischemia-reperfusion injury in rats

, 1999
As a preliminary investigation to exploring whether the methylenedioxy group and the cyclooctadiene ring of the dibenzo[a,c]cyclooctadiene (schisandrin) molecule plays an important role in the protection against myocardial ischemia-reperfusion (IR ...
Ko, Kam Ming, Yim, Tze Kin
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Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Schisandrin B protects against tacrine- and bis(7)-tacrine-induced hepatotoxicity and enhances cognitive function in mice

, 2002
Intragastric administration (100-200 μmol/kg) of tacrine (THA) or bis(7)-THA could cause an acute and dose-dependent increase in plasma alanine aminotransferases activity in mice at 6 h after the drug administration.
Ko, K. M., Mak, D. H.F., Han, Y. F., Carlier, P. R., Lam, B. Y.H., Pang, Y. P., Pan, S. Y.   +6 more
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Schisandrin B from Schisandra chinensis reduces hepatic lipid contents in hypercholesterolaemic mice

, 2008
The effects of schisandrin B (Sch B) on liver and serum lipid contents were investigated in mice with experimentally-induced hypercholesterolaemia. Hypercholesterolaemia was induced either by oral administration of a cholesterol/bile salts mixture (2/0 ...
Fang, Hai-Yan, Zhao, Xing Ye, Dong, Hang, Pan, Si Yuan, Ko, Kam Ming, Yu, Zhi-Ling, Zhao, Xing-Ye, Yu, Zhi Ling, Xiang, Chun-Jing, Fang, Hai Yan, Pan, Si-Yuan, Ko, Kam-Ming, Fong, Wang Fun, Xiang, Chun Jing, Fong, Wang-Fun   +14 more
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Suppressive effect of Schisandrin B on TGFβ1-induced NF-κB activation in vascular smooth muscle cells [PDF]

, 2013
학위논문 (석사)-- 서울대학교 대학원 : 의과학과 의과학 전공, 2013. 2. 전주홍.TGF β1 is involved in the pathogenesis of vascular diseases through modulating various signaling pathways including NF-κB. Schisandra chinensis (S.
김재경
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Schisandrin B co-treatment ameliorates the impairment on mitochondrial antioxidant status in various tissues of long-term ethanol treated rats

, 2010
The effect of schisandrin B (Sch B) on long-term ethanol-induced oxidative stress in various rat tissues was investigated. Long-term ethanol treatment increased reactive oxygen metabolites (ROM) level in plasma.
Chen, Na, Lam, Philip Y., Ko, Kam Ming, Leung, Hoi Yan, Chiu, Po Yee, Leong, Pou Kuan   +5 more
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Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity

, 2015
Yi Zhang,1,2 Zhi-Wei Zhou,2 Hua Jin,2 Chengbin Hu,2 Zhi-Xu He,3 Zhi-Ling Yu,4 Kam-Ming Ko,5 Tianxin Yang,6 Xueji Zhang,7 Si-Yuan Pan,1 Shu-Feng Zhou2 1Department of Pharmacology, School of Chinese Materia Medica, Beijing University of Chinese Medicine ...
Hu C, Zhou ZW, Jin H, He ZX, Pan SY, Zhou SF, Zhang Y, Zhang X, Yang T, Yu ZL, Ko KM   +10 more
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Process development for separation and purification of schisandrin B stereoisomer from fructus schisandrae

, 2007
Schisandrin B (Sch B), the most abundant and biologically active dibenzocyclooctadiene lignan present in Fructus Schisandrae (FS), is usually prepared and supplied in the form of a mixture of its stereoisomers, namely (±)γ-schisandrin and (–)Sch B ...
Luk, Ka Fai
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