Results 41 to 50 of about 12,357,672 (189)

Hepatoprotective Constituents of Total Dibenzocyclooctadiene Lignans from Schisandra chinensis Based on the Spectrum-Effect Relationship

open access: yesMolecules, 2021
To scientifically clarify the hepatoprotective constituents of Fructus Schizandrae chinensis, eleven batches samples of total dibenzocyclooctadiene lignans (TDL) from Schisandra chinensis were prepared by using the optimum extraction technique ...
Lu-Lu Deng   +6 more
doaj   +1 more source

An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism

open access: yesFrontiers in Pharmacology, 2021
Liver disease is a major cause of illness and death worldwide. In China, liver diseases, primarily alcoholic and nonalcoholic fatty liver disease, and viral hepatitis, affect approximately 300 million people, resulting in a major impact on the global ...
Yuan Gao   +18 more
doaj   +1 more source

Schisandrin B Antagonizes Cardiotoxicity Induced by Pirarubicin by Inhibiting Mitochondrial Permeability Transition Pore (mPTP) Opening and Decreasing Cardiomyocyte Apoptosis

open access: yesFrontiers in Pharmacology, 2021
Objective: Pirarubicin (THP), one of the anthracycline anticancer drugs, is widely used in the treatment of various cancers, but its cardiotoxicity cannot be ignored.
Hongwei Shi   +11 more
doaj   +1 more source

Determination of Schisandrin A and Schisandrin B in Traditional Chinese Medicine Preparation Huganpian Tablet by RP-HPLC

open access: yesChemical and Pharmaceutical Bulletin, 2019
A reverse phase (RP)-HPLC method for separation and determination of Schisandrin A and Schisandrin B was presented, using a C18 Bondclone column, with methanol-water (v/v = 68 : 32) as mobile phase at a flow-rate of 1.00 mL·min-1, and UV detection at 220 nm. The tested parameters included mobile phase composition and UV detection wavelength.
Yu, Bingsheng   +2 more
openaire   +3 more sources

Involvement of PI3K/Akt/β-catenin signaling in schisandrin B-mitigated bone deterioration in an experimental rat model of estrogen deficiency

open access: yesArchives of Medical Science, 2020
Introduction Schisandrin B (SchB) has been reported to perform a wide range of biological functions, including antioxidant activity, anti-inflammatory activity and stimulation of osteoblast proliferation.
Yimin Liang, Wei Li, Xiang Li, Jun Nan
doaj   +1 more source

Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells

open access: yesThe Journal of Membrane Biology, 2023
Abstract Osteoarthritis is a common joint disease characterized by damage to the joint cartilage that occurs throughout the entire joint tissue. This damage primarily manifests as pain in the affected area. In clinical practice, medication is commonly used to relieve pain, but the treatment’s effectiveness is poor and recurrent attacks are ...
Fei Hu, WenJie Hu, Hongming Xu
openaire   +2 more sources

A Novel Mouse Model of Combined Hyperlipidemia Associated With Steatosis and Liver Injury by a Single-Dose Intragastric Administration of Schisandrin B/Cholesterol/Bile Salts Mixture

open access: yesJournal of Pharmacological Sciences, 2013
Hyperlipidemia is referred to as hypercholesterolemia, hypertriglyceridemia, or both in combined hyperlipidemia. Here, a novel mouse model of combined hyperlipidemia is described.
Si-Yuan Pan   +8 more
doaj   +1 more source

Ethanol extract of Schisandrae chinensis fructus ameliorates the extent of experimentally induced atherosclerosis in rats by increasing antioxidant capacity and improving endothelial dysfunction

open access: yesPharmaceutical Biology, 2018
Context: Schisandrae chinensis fructus, the dried ripe fruit of Schisandra chinensis (Turcz.) Baill. (Magnoliaceae) has been used for thousands of years as a traditional Chinese herb, which can attenuate and prevent the development of cardiovascular ...
Xiu Chen   +13 more
doaj   +1 more source

Schisandrin B: A Double‐Edged Sword in Nonalcoholic Fatty Liver Disease [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2016
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver lesions ranging from hepatic steatosis, nonalcoholic steatohepatitis, hepatic cirrhosis, and hepatocellular carcinoma. The high global prevalence of NAFLD has underlined the important public health implications of this disease.
Pou Kuan Leong, Kam Ming Ko
openaire   +3 more sources

Chemical structures of Schisandrin A and Schisandrin B.

open access: yes, 2016
Chemical structures of Schisandrin A and Schisandrin B.
Kam Ming Ko (1936198)   +5 more
core   +1 more source

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