Results 21 to 30 of about 2,730 (205)

Schisandrin B for Treatment of Male Infertility [PDF]

open access: yesSSRN Electronic Journal, 2020
AbstractThe decline of male fertility and its consequences on human populations are important public-health issues. However, there are limited choices for treatment of male infertility. In an attempt to identify a compound that could promote male fertility, we identified and characterized a library of small molecules from an ancient formulation Wuzi ...
Di-Xin Zou   +13 more
openaire   +2 more sources

The influence of dibenzocyclooctadiene lignans on macrophage glutathione and lipid metabolism associated with Chlamydia pneumoniae-induced foam cell formation

open access: yesAdvances in Redox Research, 2021
Triggered by changes in macrophage redox status and lipid metabolism, foam cells represent a hallmark of atherosclerosis. Induction of macrophage foam cell formation by Chlamydia pneumoniae, a gram-negative human pathogen, has been established in various
Maarit Kortesoja   +2 more
doaj   +1 more source

A Comprehensive Review on Schisandrin B and Its Biological Properties. [PDF]

open access: yesOxid Med Cell Longev, 2020
Nature is a vast source of bioactive molecules and has provided an active and efficient reservoir for drug discovery. Among natural compounds, one of the most promising is Schisandrin B (Sch B), isolated from Schisandra chinensis, which was documented to possess diversified pharmacokinetic propriety, among them antioxidant, anti-inflammation ...
Nasser MI   +6 more
europepmc   +5 more sources

Inhibitory effect of Schisandrin on the pharmacokinetics of poziotinib in vivo and in vitro by UPLC‐MS/MS

open access: yesThoracic Cancer, 2023
Background As a pan‐HER tyrosine kinase inhibitor with a promising application prospect, poziotinib is likely to be coadministered with Schisandrins in clinical treatment due to its anticancer activities.
Shuanghu Wang   +7 more
doaj   +1 more source

Schisandrin B-mediated TH17 cell differentiation attenuates bowel inflammation

open access: yesPharmacological Research, 2021
Schisandrin B (Sch B) is the major active constituent of the traditional Chinese medicine Schisandra chinensis and has anti-inflammatory activity, but the target of Sch B remains unclear. T helper 17 (TH17) cells have been involved in the pathogenesis of many autoimmune and inflammatory diseases.
Zeyu, Ma   +9 more
openaire   +2 more sources

Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells

open access: yesThe Journal of Membrane Biology, 2023
Abstract Osteoarthritis is a common joint disease characterized by damage to the joint cartilage that occurs throughout the entire joint tissue. This damage primarily manifests as pain in the affected area. In clinical practice, medication is commonly used to relieve pain, but the treatment’s effectiveness is poor and recurrent attacks are ...
Fei Hu, WenJie Hu, Hongming Xu
openaire   +2 more sources

Schisandrin C Affects Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells and Glucose Uptake in Skeletal Muscle Cells

open access: yesMolecules, 2021
The aim of our study was to investigate the effect of three lignans (schisandrol A, schisandrol B, and schisandrin C) on insulin secretion in rat INS-1 pancreatic β-cells and glucose uptake in mouse C2C12 skeletal muscle cells.
Dahae Lee   +6 more
doaj   +1 more source

Screening of Botanical Drugs against SARS-CoV-2 Entry Reveals Novel Therapeutic Agents to Treat COVID-19

open access: yesViruses, 2022
An escalating pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has severely impacted global health. There is a severe lack of specific treatment options for diseases caused by SARS-CoV-2.
Junyuan Cao   +10 more
doaj   +1 more source

Accumulation of dibenzocyclooctadiene lignans in agar cultures and in stationary and agitated liquid cultures of Schisandra chinensis (Turcz.) Baill [PDF]

open access: yes, 2015
Schisandra chinensis plant in vitro cultures were maintained on Murashige and Skoog (MS) medium supplemented with 3 mg/l 6-benzyladenine (BA) and 1 mg/l 1-naphthaleneacetic acid (NAA) in an agar system and also in two different liquid systems: stationary
Adam Bucinski   +5 more
core   +1 more source

Hepatoprotective Constituents of Total Dibenzocyclooctadiene Lignans from Schisandra chinensis Based on the Spectrum-Effect Relationship

open access: yesMolecules, 2021
To scientifically clarify the hepatoprotective constituents of Fructus Schizandrae chinensis, eleven batches samples of total dibenzocyclooctadiene lignans (TDL) from Schisandra chinensis were prepared by using the optimum extraction technique ...
Lu-Lu Deng   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy