Results 21 to 30 of about 1,905 (169)
Schisandrin B Attenuates Hepatic Stellate Cell Activation and Promotes Apoptosis to Protect against Liver Fibrosis. [PDF]
Molecules, 2021 The activation of hepatic stellate cells (HSC) plays a key role in the progression of hepatic fibrosis, it is essential to remove activated HSC through apoptosis to reverse hepatic fibrosis.
Li Z +5 more
europepmc +2 more sources
A Comprehensive Review on Schisandrin B and Its Biological Properties. [PDF]
Oxid Med Cell Longev, 2020 Nature is a vast source of bioactive molecules and has provided an active and efficient reservoir for drug discovery. Among natural compounds, one of the most promising is Schisandrin B (Sch B), isolated from Schisandra chinensis, which was documented to possess diversified pharmacokinetic propriety, among them antioxidant, anti-inflammation ...
Nasser MI +6 more
europepmc +5 more sources
Prevention of the Pro-Aggressive Effects of Ethanol-Intoxicated Mice by Schisandrin B. [PDF]
Nutrients, 2023 Excessive alcohol consumption can lead to serious health complications, with liver and neurological complications being the most important. In Western nations, alcoholic liver disease accounts for 50% of mortality from end-stage liver disease and is the second most common cause of liver transplants.
Lam HYP, Liang TR, Peng SY.
europepmc +3 more sources
The Effect of Schisandrin B on the Development of Multiple Sclerosis [PDF]
The 3rd International conference on Natural Products for Cancer Prevention and Therapy, 2019 Multiple Sclerosis (MS) is a chronic inflammatory, demyelinating neurodegenerative disease targeting the central nervous system. The pathogenesis of MS is a process of innate and adaptive immune system components. In particular, Th17 and Treg balance play an important role in the pathogenesis of MS.
Mustafa Cakir +3 more
openaire +4 more sources
Chemical and Pharmaceutical Bulletin, 2019 A reverse phase (RP)-HPLC method for separation and determination of Schisandrin A and Schisandrin B was presented, using a C18 Bondclone column, with methanol-water (v/v = 68 : 32) as mobile phase at a flow-rate of 1.00 mL·min-1, and UV detection at 220 nm. The tested parameters included mobile phase composition and UV detection wavelength.
Yu, Bingsheng +2 more
openaire +3 more sources
Production of Schisandrin A and Schisandrin B from Callus and Suspension Cell Cultures of Schisandra chinensis [PDF]
Natural Product Communications, 2017 For establishing the fermentation system of synthetic schizandrin A and schizandrin B, culture conditions of the Schisandra chinensis callus and the suspension cell were studied in this paper. The friable calluses of Schisandra chinensis (Turcz.) Baill.
Yong-Qiang Zhou +2 more
openaire +1 more source
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells
The Journal of Membrane Biology, 2023 Abstract Osteoarthritis is a common joint disease characterized by damage to the joint cartilage that occurs throughout the entire joint tissue. This damage primarily manifests as pain in the affected area. In clinical practice, medication is commonly used to relieve pain, but the treatment’s effectiveness is poor and recurrent attacks are ...
Fei Hu, WenJie Hu, Hongming Xu
openaire +2 more sources
, 2021 Background. Asthma is a complex inflammatory disorder that plagues a large number of people. Schisandrin B is an active ingredient of the traditional Chinese herbal medicine Schisandra with various proven physiological activities such as anti ...
Yaqin Chen +6 more
core +1 more source
Schisandrin B: A Double‐Edged Sword in Nonalcoholic Fatty Liver Disease [PDF]
Oxidative Medicine and Cellular Longevity, 2016 Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver lesions ranging from hepatic steatosis, nonalcoholic steatohepatitis, hepatic cirrhosis, and hepatocellular carcinoma. The high global prevalence of NAFLD has underlined the important public health implications of this disease.
Pou Kuan Leong, Kam Ming Ko
openaire +3 more sources
, 2023 Background As a pan‐HER tyrosine kinase inhibitor with a promising application prospect, poziotinib is likely to be coadministered with Schisandrins in clinical treatment due to its anticancer activities.
Yunfang Zhou +7 more
core +1 more source