Results 11 to 20 of about 1,905 (169)

A Simple and Convenient Method for Simultaneous Determination ofSchizandrol A,Schizandrol B,Schisandrin A,γ-Schisandrin, andSchisandrin C [PDF]

Journal of Chemistry, 2016
A simple, rapid, and specific HPLC method was established for simultaneous determination of five major lignans (Schizandrol A,Schizandrol B,Schisandrin A,γ-Schisandrin, andSchisandrin C) inSchisandra chinensis. The five lignans can be separated completely on Kromasil C18column (250 nm × 4.6 nm) and then detected at 254 nm using methanol (mobile phase A)
Yu Zhou, Wu Ling Wei, Jiang Xing Hua, Qingsheng Fan   +3 more
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Separation and purification of (−)schisandrin B from schisandrin B stereoisomers

Biochemical Engineering Journal, 2008
Abstract Schisandrin B (Sch B), consisting of a mixture of its stereoisomers, namely (−)Sch B and (±)γ-schisandrin, is the most abundant and biologically active dibenzocyclooctadiene lignan present in Fructus Schisandrae (FS). The objective of this study is to develop a process for large-scale separation and purification of a single stereoisomer of ...
Luk, Ka Fai SENG, Ko, Robert Kam Ming, Ng, Ka Ming   +2 more
openaire   +3 more sources

Schisandrin B regulates lipid metabolism in subcutaneous adipocytes

Scientific Reports, 2017
AbstractSubcutaneous adipocytes in obese subjects have a lower sensitivity to catecholamine-induced lipolysis and a higher sensitivity to insulin anti-lipolytic effects compared to adipocytes in other adipose depots. Therefore, increasing lipolysis in subcutaneous adipocytes coupled with enhanced fatty acid oxidation may be an anti-obesity strategy ...
Kwan, Hiu Yee, Wu, Jiahui, Su, Tao, Chao, Xiao-Juan, Yu, Hua, Liu, Bin, Fu, Xiuqiong, Tse, Anfernee Kai Wing, Chan, Chi Leung, Fong, Wang Fun, Yu, Zhi-ling   +10 more
openaire   +3 more sources

Schisandrin B as a Hormetic Agent for Preventing Age-Related Neurodegenerative Diseases [PDF]

Oxidative Medicine and Cellular Longevity, 2012
Oxidative stress and mitochondrial dysfunction have been implicated in the pathogenesis of neurodegenerative diseases, with the latter preceding the appearance of clinical symptoms. The energy failure resulting from mitochondrial dysfunction further impedes brain function, which demands large amounts of energy.
Lam, Yeung LIFS, Ko, Robert K.M.
openaire   +4 more sources

Prevention and Treatment of Doxorubicin-Induced Cardiotoxicity by Dexrazoxane and Schisandrin B in Rabbits

International Journal of Toxicology, 2011
The cost of dexrazoxane, a drug used to provide protection from doxorubicin-induced cardiotoxicity, limits its use in low-income countries. We aimed to see whether schisandrin B, an inexpensive drug, could provide protection equivalent to that provided by dexrazoxane.
Feifei, Che, Yu, Liu, Caigang, Xu
openaire   +3 more sources

Separation and Purification of Schisandrin B from Fructus Schisandrae

Industrial & Engineering Chemistry Research, 2008
Schisandrin B (Sch B) is the most abundant and biologically active dibenzocyclooctadiene lignan present in Fructus Schisandrae (FS). It is a highly desirable ingredient for a dietary supplement. While Sch B has been isolated from FS in the laboratory, the experimental procedure was usually lengthy and the yield was relatively low. The objective of this
Luk, Ka Fai SENG, Ko, Robert Kam Ming, Ng, Ka Ming   +2 more
openaire   +3 more sources

Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response

PLOS ONE, 2016
Schisandrin A (Sch A) and schisandrin B (Sch B) are active components of Schisandrae Fructus. We compared the biochemical mechanism underlying the anti-inflammatory action of Sch A and Sch B, using cultured lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and concanavalin (ConA)-stimulated mouse splenocytes.
Leong, Pou Kuan, Wong, Hoi Shan, Chen, Jihang, Chan, Wing Man, Leung, Hoi Yan, Ko, Kam Ming   +5 more
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In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice. [PDF]

Int J Mol Sci, 2023
The aim of this study is to evaluate the anticonvulsant potential of schisandrin B, a main ingredient of Schisandra chinensis extracts. Schisandrin B showed anticonvulsant activity in the zebrafish larva pentylenetetrazole acute seizure assay but did not
Nieoczym D, Banono NS, Stępnik K, Kaczor AA, Szybkowski P, Esguerra CV, Kukula-Koch W, Gawel K.   +7 more
europepmc   +2 more sources

Schisandrin B for the treatment of male infertility. [PDF]

Clin Transl Med, 2021
Zou DX, Meng XD, Xie Y, Liu R, Duan JL, Bao CJ, Liu YX, Du YF, Xu JR, Luo Q, Zhao CJ, Zhang Z, Ma S, Yang WP, Lin RC, Lu WL.   +15 more
europepmc   +5 more sources

Schisandrin B for Treatment of Male Infertility [PDF]

SSRN Electronic Journal, 2020
Abstract The decline of male fertility and its consequences on human populations are important public-health issues. However, there are limited choices for treatment of male infertility. In an attempt to identify a compound that could promote male fertility, we identified and characterized a library of small molecules
Di-Xin Zou, Xue-Dan Meng, Ying Xie, Rui Liu, Jia-Lun Duan, Yi-Xuan Liu, Ya-Fei Du, Jia-Rui Xu, Qian Luo, Zhan Zhang, Shuang Ma, Wei-Peng Yang, Rui-Chao Lin, Wan-Liang Lu   +13 more
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