Results 11 to 20 of about 12,357,672 (189)

A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C [PDF]

Journal of Chemistry, 2016
A simple, rapid, and specific HPLC method was established for simultaneous determination of five major lignans (Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C) in Schisandra chinensis.
Yu Zhou, Wu Ling Wei, Jiang Xing Hua, Qingsheng Fan   +3 more
doaj   +4 more sources

Schisandrin B for the treatment of male infertility [PDF]

Clinical and Translational Medicine, 2021
Di‐Xin Zou, Xue‐Dan Meng, Ying Xie, Rui Liu, Jia‐Lun Duan, Chun‐Jie Bao, Yi‐Xuan Liu, Ya‐Fei Du, Jia‐Rui Xu, Qian Luo, Chong‐jun Zhao, Zhan Zhang, Shuang Ma, Wei‐Peng Yang, Rui‐Chao Lin, Wan‐Liang Lu   +15 more
doaj   +5 more sources

Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response.

PLoS ONE, 2016
Schisandrin A (Sch A) and schisandrin B (Sch B) are active components of Schisandrae Fructus. We compared the biochemical mechanism underlying the anti-inflammatory action of Sch A and Sch B, using cultured lipopolysaccharide (LPS)-stimulated RAW264.7 ...
Pou Kuan Leong, Hoi Shan Wong, Jihang Chen, Wing Man Chan, Hoi Yan Leung, Kam Ming Ko   +5 more
doaj   +5 more sources

Schisandrin B Attenuates Hepatic Stellate Cell Activation and Promotes Apoptosis to Protect against Liver Fibrosis

Molecules, 2021
The activation of hepatic stellate cells (HSC) plays a key role in the progression of hepatic fibrosis, it is essential to remove activated HSC through apoptosis to reverse hepatic fibrosis.
Zhiman Li, Lijuan Zhao, Yunshi Xia, Jianbo Chen, Mei Hua, Yinshi Sun   +5 more
doaj   +2 more sources

Schisandrin B Attenuates Airway Inflammation by Regulating the NF-κB/Nrf2 Signaling Pathway in Mouse Models of Asthma

Journal of Immunology Research, 2021
Background. Asthma is a complex inflammatory disorder that plagues a large number of people. Schisandrin B is an active ingredient of the traditional Chinese herbal medicine Schisandra with various proven physiological activities such as anti ...
Yaqin Chen, Yu Kong, Qili Wang, Jian Chen, Hua Chen, Huihui Xie, Lan Li   +6 more
doaj   +2 more sources

Inhibitory effect of Schisandrin on the pharmacokinetics of poziotinib in vivo and in vitro by UPLC‐MS/MS

Thoracic Cancer, 2023
Background As a pan‐HER tyrosine kinase inhibitor with a promising application prospect, poziotinib is likely to be coadministered with Schisandrins in clinical treatment due to its anticancer activities.
Shuanghu Wang, Mengming Xia, Yu Wang, Zebei Lu, Peiwu Geng, Dapeng Dai, Yunfang Zhou, Qingjun Wu   +7 more
doaj   +2 more sources

Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice

Biomolecules, 2020
Currently, Angiostrongylus cantonensis infections are predominantly treated with albendazole. However, the use of albendazole can provoke certain neurological symptoms as a result of the immune response triggered by the dead worms.
Ho Yin Pekkle Lam, Ting-Ruei Liang, Shinn-Jong Jiang, Shih-Yi Peng   +3 more
doaj   +2 more sources

Separation and purification of (−)schisandrin B from schisandrin B stereoisomers

Biochemical Engineering Journal, 2008
Abstract Schisandrin B (Sch B), consisting of a mixture of its stereoisomers, namely (−)Sch B and (±)γ-schisandrin, is the most abundant and biologically active dibenzocyclooctadiene lignan present in Fructus Schisandrae (FS). The objective of this study is to develop a process for large-scale separation and purification of a single stereoisomer of ...
Luk, Ka Fai SENG, Ko, Robert Kam Ming, Ng, Ka Ming   +2 more
openaire   +3 more sources

Schisandrin C Affects Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells and Glucose Uptake in Skeletal Muscle Cells

Molecules, 2021
The aim of our study was to investigate the effect of three lignans (schisandrol A, schisandrol B, and schisandrin C) on insulin secretion in rat INS-1 pancreatic β-cells and glucose uptake in mouse C2C12 skeletal muscle cells.
Dahae Lee, Young-Mi Kim, Hyun Woo Kim, You-Kyoung Choi, Bang Ju Park, Sang Hoon Joo, Ki Sung Kang   +6 more
doaj   +2 more sources

Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways

Drug Design, Development and Therapy, 2018
Jisheng Ran,* Chiyuan Ma,* Kai Xu,* Langhai Xu, Yuzhe He, Safwat Adel Abdo Moqbel, Pengfei Hu, Lifeng Jiang, Weiping Chen, Jiapeng Bao, Yan Xiong, Lidong Wu Department of Orthopedic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang ...
Ran J, Ma C, Xu K, Xu L, He Y, Moqbel SAA, Hu P, Jiang L, Chen W, Bao J, Xiong Y, Wu L   +11 more
doaj   +1 more source