Results 51 to 60 of about 2,730 (205)
Differential Effect of Schisandrin B Stereoisomers on ATR-Mediated DNA Damage Checkpoint Signaling
Journal of Pharmacological Sciences, 2013 We have previously reported that schisandrin B (SchB) is a specific inhibitor of ATR (ataxia telangiectasia and Rad-3-related) protein kinase. Since SchB consists of a mixture of its diastereomers gomisin N (GN) and γ-schisandrin (γ-Sch), the inhibitory ...
Naoto Tatewaki +6 more
doaj +1 more source
Inhibitory effects of Schisandrin�B on human prostate cancer cells
Oncology Reports, 2018 Prostate cancer is a serious affliction worldwide. Although much progress has been made in the study of prostate cancer prevention and treatment, less attention has been paid to the molecular mechanism of the disease. The molecular arrangement by which Schisandrin B (Sch B) induces human prostate cancer cytotoxicity was comprehensively examined in the ...
Moussa Ide, Nasser +4 more
openaire +3 more sources
Schisandrin B Induces Apoptosis and Cell Cycle Arrest of Gallbladder Cancer Cells [PDF]
Molecules, 2014 Gallbladder cancer, with high aggressivity and extremely poor prognosis, is the most common malignancy of the bile duct. The main objective of the paper was to investigate the effects of schisandrin B (Sch B) on gallbladder cancer cells and identify the mechanisms underlying its potential anticancer effects. We showed that Sch B inhibited the viability
Shan-Shan Xiang +18 more
openaire +3 more sources
Potential effectiveness of traditional Chinese medicine for cardiac syndrome X (CSX): a systematic review and meta-analysis [PDF]
, 2013 BACKGROUND: Treatment of cardiac syndrome X with unknown pathological mechanism remains a big challenge for clinicians. Complementary and alternative medicine may bring a new choice for its management.
Hongcai Shang +6 more
core +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Chinese Medicine, 2023 Background Traditional Chinese medicine (TCM) posits that Chinese medicinal materials can only be clinically used after being processed and prepared into decoction pieces.
Zhongyuan Qu +7 more
doaj +1 more source
Rapeseed oil-rich diet alters in vitro menadione and nimesulide hepatic mitochondrial toxicity [PDF]
, 2013 Diet-induced changes in the lipid composition of mitochondrial membranes have been shown to influence physiological processes. However, the modulation effect of diet on mitochondrially-active drugs has not yet received the deserved attention.
Jurado, A. S. +3 more
core +1 more source
eFood, Volume 7, Issue 3, June 2026.Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam +4 more
wiley +1 more source
Molecules, 2018 Schisandra rubriflora is a dioecious plant of increasing importance due to its lignan composition, and therefore, possible therapeutic properties. The aim of the work was lignan profiling of fruits, leaves and shoots of female (F) and male (M) plants ...
Agnieszka Szopa +5 more
doaj +1 more source
Suppressive effects of medicinal plants and their derivatives on inflammasome complex: A systematic review [PDF]
, 2016 Inflammasome activation is mediated by (NOD)-like receptors (NLR) proteins that respond to stimuli. Among NLRs, NACHT-LRR and PYD domains-containing protein 3 (NLRP3) senses the widest array of stimuli.
Asadi-Samani, Majid. +4 more
core