Results 111 to 120 of about 2,730 (205)

Protective effects on myocardial infarction model: delivery of schisandrin B using matrix metalloproteinase-sensitive peptide-modified, PEGylated lipid nanoparticles

International Journal of Nanomedicine, 2017
Mingfeng Shao,1 Wenfang Yang,2 Guangying Han1 1Department of Cardiology, Linyi People’s Hospital, Linyi, Shandong, People’s Republic of China; 2Department of Internal Medicine, Linyi Hot Spring Hospital of Shandong Coal ...
Shao M, Yang W, Han G
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Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin

Scientific Reports, 2017
Acquired drug resistance poses a great challenge in cancer therapy. Drug efflux and anti-apoptotic processes are the most two common mechanisms that confer cancer drug resistance.
Shengpeng Wang, Anqi Wang, Min Shao, Ligen Lin, Peng Li, Yitao Wang   +5 more
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Schisandrin B attenuates CCl4-induced liver fibrosis in rats by regulation of Nrf2-ARE and TGF-β/Smad signaling pathways

Drug Design, Development and Therapy, 2017
Qingshan Chen,1,* Hai Zhang,2,* Yan Cao,3 Ying Li,1 Sen Sun,1 Junping Zhang,4 Guoqing Zhang1 1Department of Pharmacy, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China, 2Department of Pharmacy, Shanghai ...
Chen QS, Zhang H, Cao Y, Li Y, Sun S, Zhang JP, Zhang GQ   +6 more
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Schisandrin B protects against angiotensin II-induced endotheliocyte deficits by targeting Keap1 and activating Nrf2 pathway

Drug Design, Development and Therapy, 2018
Jibo Han,* Xiaowen Shi,* Zhanxiong Zheng, Bin Zhang, Fengjie Shi, Liqin Jiang, Jianjiang Xu Department of Cardiology, Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, China *These authors contributed equally to this work ...
Han J, Shi X, Zheng Z, Zhang B, Shi F, Jiang L, Xu J   +6 more
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Combined Schisandrin B and Temozolomide Treatment Induces Mitochondrial Apoptosis in Glioma Cells

Frontiers in Bioscience-Landmark
Background: Temozolomide (TMZ) is a standard chemotherapeutic agent for glioma, but prolonged use frequently leads to drug resistance, reducing its therapeutic efficacy.
Zebo Tang, Chaoran Guo, Na Wen, Hong Jin, Yuan Dong, Bo Xu, Xiangyu Ma, Liu Han, Jianxin Liu   +8 more
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In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice. [PDF]

Int J Mol Sci, 2023
Nieoczym D, Banono NS, Stępnik K, Kaczor AA, Szybkowski P, Esguerra CV, Kukula-Koch W, Gawel K.   +7 more
europepmc   +1 more source

Identification of Quality Markers in Schisandra chinensis (Turcz.) Baill. Using UPLC-Q-Extractive Orbitrap/MS, Chemometric Analysis, and Network Pharmacology

Separations
Chemical composition is a critical factor for determining the efficacy of any traditional Chinese medicine (TCM) and can be used as an indicator of commercial quality. To develop a new strategy for discovering potential quality markers (Q-markers) of TCM
Yinpeng Wang, Yumei Li, Yan Ding, Xinxin Du, Jingbo Zhu   +4 more
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Prevention of the Pro-Aggressive Effects of Ethanol-Intoxicated Mice by Schisandrin B. [PDF]

Nutrients, 2023
Lam HYP, Liang TR, Peng SY.
europepmc   +1 more source

The protective effects of aqueous extract of Schisandra sphenanthera against alcoholic liver disease partly through the PI3K-AKT-IKK signaling pathway

Heliyon
Purpose: This study aimed to investigated the key chemical components and the effect of the aqueous extract of Schisandra sphenanthera (SSAE) on alcoholic liver disease (ALD) and the related molecular mechanism. Methods: This study employed UPLC-Q-TOF-MS/
Ding Liu, Kai Yang, Taotao Li, Tiantian Tang, Yujiao Wang, Wenfei Wang, Jia Li, Peijie Zhou, Xuan Wang, Chongbo Zhao, Dongyan Guo, Yundong Xie, Jiangxue Cheng, Mei Wang, Jing Sun, Xiaofei Zhang   +15 more
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Schisandrin B elicits the Keap1-Nrf2 defense system via carbene reactive metabolite which is less harmful to mice liver

Drug Design, Development and Therapy, 2018
Shan Feng,* Bingxun Qiu,* Li Zou, Ke Liu, Xiaoyu Xu, Huifeng Zhu College of Pharmaceutical Sciences and Chinese Medicine, Southwest University, Beibei, Chongqing 400715, China *These authors contributed equally to this work Background: Schisandrin B ...
Feng S, Qiu B, Zou L, Liu K, Xu X, Zhu H
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