Schisandrin B promotes hepatic differentiation from human umbilical cord mesenchymal stem cells. [PDF]
Jin M +14 more
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Schisandrin B Suppresses Colon Cancer Growth by Inducing Cell Cycle Arrest and Apoptosis: Molecular Mechanism and Therapeutic Potential. [PDF]
Co VA +10 more
europepmc +1 more source
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss. [PDF]
Wang J +9 more
europepmc +1 more source
The Use of Schisandrin B to Combat Triple-Negative Breast Cancers by Inhibiting NLRP3-Induced Interleukin-1β Production. [PDF]
Chang CM, Liang TR, Lam HYP.
europepmc +1 more source
[Retracted] Schisandrin B inhibits epithelial‑mesenchymal transition and stemness of large‑cell lung cancer cells and tumorigenesis in xenografts via inhibiting the NF‑κB and p38 MAPK signaling pathways. [PDF]
Li S, Wang H, Ma R, Wang L.
europepmc +1 more source
Schisandrin B, a dual positive allosteric modulator of GABAA and glycine receptors, alleviates seizures in multiple mouse models. [PDF]
Wu J +5 more
europepmc +1 more source
A novel experimental model of acute hypertriglyceridemia induced by schisandrin B
Mice were intragastrically treated with single doses (0.05-0.8 g/kg) of schisandrin B (a dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis). Twenty-four hours after schisandrin B administration, the serum triglyceride level was increased by 10-235% in a dose-dependent manner.
Si-Yuan Pan, Yifan Han, Wen-Yuan Li
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Schisandrin B—A novel inhibitor of P-glycoprotein
Biochemical and Biophysical Research Communications, 2005P-glycoprotein-mediated drug efflux is one of the major causes of the cancer multidrug resistance (MDR). Inhibition of P-glycoprotein could reverse cancer MDR. Here, we show that schisandrin B, a naturally occurring compound from Schisandra chinensis (Turcz.) Baill, bears strong potency to inhibit P-glycoprotein.
Xun Hu
exaly +3 more sources
Schisandrin B protects against solar irradiation-induced oxidative stress in rat skin tissue
Schisandrin B (Sch B) and schisandrin C (Sch C), but not schisandrin A and dimethyl diphenyl bicarboxylate, protected rat skin tissue against solar irradiation-induced oxidative injury, as evidenced by a reversal of solar irradiation-induced changes in ...
Philip Y Lam, Hoi Yan Leung, Kam Ming Ko
exaly +2 more sources
Schisandrin B promotes TH1 cell differentiation by targeting STAT1
International Immunopharmacology, 2021Schisandrin B (Sch B) is the major active ingredient of the traditional Chinese medicine Schisandra chinensis and has antitumor activity, anti-inflammatory activity. CD4+ Th subsets orchestrate immune responses to plenty of pathogen infections and participate in the pathogenesis of many immune-related diseases.
Jufeng Guo +4 more
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