Results 11 to 20 of about 45,524 (260)
European Journal of Biology, 2023 Objective: Metformin, a well-known anti-diabetic drug and a caloric restriction mimetic, seems to attenuate aging through myriad cellular processes, wherein most of its mode of action is still elusive.
Çağatay Tarhan +2 more
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Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics. [PDF]
PLoS ONE, 2016 Schizosaccharomyces pombe is an outstanding model organism for cell biological investigations, yet the range of useful and well-characterized fluorescent proteins (XFPs) is limited.
Bassem Al-Sady +4 more
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Protein prenylation in Schizosaccharomyces pombe [PDF]
FEBS Letters, 1992 S. pombe is shown to be a powerful system for studies concerning attachment or polyisoprenoid moieties to proteins, due to its ability to take up exogenous mevalonic acid efficiently. The fission yeast can take up about 5% of the exogenously added mevalonic acid and incorporate ∼10% of this into protein.
Giannakouros, Thomas +2 more
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Epigenetics & Chromatin, 2022 Budding yeast Saccharomyces cerevisiae and fission yeast Schizosaccharomyces pombe are good models for heterochromatin study. In S. pombe, H3K9 methylation and Swi6, an ortholog of mammalian HP1, lead to heterochromatin formation. However, S.
Junsoo Oh +3 more
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Vacuolar protein sorting receptor in Schizosaccharomyces pombe [PDF]
Microbiology, 2006 The mechanism by which soluble proteins, such as carboxypeptidase Y, reach the vacuole inSaccharomyces cerevisiaeis very similar to the mechanism of lysosomal protein sorting in mammalian cells. Vps10p is a receptor for transport of soluble vacuolar proteins inS. cerevisiae.vps10+, a gene encoding a homologue ofS.
Tomoko, Iwaki +7 more
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Explaining lengths and shapes of yeast by scaling arguments. [PDF]
PLoS ONE, 2009 Lengths and shapes are approached in different ways in different fields: they serve as a read-out for classifying genes or proteins in cell biology whereas they result from scaling arguments in condensed matter physics.
Daniel Riveline
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Mechanism of assembly of snRNP cores assisted by ICln and the SMN complex in fission yeast
iScience, 2023 Summary: The spliceosomal snRNP cores, each comprised of a snRNA and a seven-membered Sm ring (D1/D2/F/E/G/D3/B), are assembled by twelve chaperoning proteins in human.
Yan Hu +7 more
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PLoS ONE, 2021 In spite of increased complexity in eukaryotes compared to prokaryotes, several basic metabolic and regulatory processes are conserved. Here we explored analogies in the eubacteria Escherichia coli and the unicellular fission yeast Schizosaccharomyces ...
Joivier Vichi +7 more
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The Schizosaccharomyces pombe Hsp104 disaggregase is unable to propagate the [PSI] prion. [PDF]
PLoS ONE, 2009 The molecular chaperone Hsp104 is a crucial factor in the acquisition of thermotolerance in yeast. Under stress conditions, the disaggregase activity of Hsp104 facilitates the reactivation of misfolded proteins. Hsp104 is also involved in the propagation
Patrick Sénéchal +4 more
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A novel DNA damage recognition protein in Schizosaccharomyces pombe [PDF]
Nucleic Acids Research, 2006 Toxic and mutagenic O6-alkylguanine adducts in DNA are repaired by O6-alkylguanine-DNA alkyltransferases (MGMT) by transfer of the alkyl group to a cysteine residue in the active site. Comparisons in silico of prokaryotes and lower eukaryotes reveal the presence of a group of proteins [alkyltransferase-like (ATL) proteins] showing amino acid sequence ...
Pearson SJ +9 more
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