Boolean network model predicts cell cycle sequence of fission yeast. [PDF]
A Boolean network model of the cell-cycle regulatory network of fission yeast (Schizosaccharomyces Pombe) is constructed solely on the basis of the known biochemical interaction topology.
Maria I Davidich, Stefan Bornholdt
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Novel TORC1 inhibitor Ecl1 is regulated by phosphorylation in fission yeast [PDF]
Extender of chronological lifespan 1 (Ecl1), which inhibits the target of rapamycin complex 1 (TORC1), physically interacts with TORC1 subunits and is necessary for appropriate cellular responses to various stressors, such as starvation, in fission yeast. Several functions of Ecl1 are suppressed by Thr7 phosphorylation when nutrients are abundant.
Hokuto Ohtsuka+10 more
wiley +2 more sources
Structure of Cdc4p, a Contractile Ring Protein Essential for Cytokinesis in Schizosaccharomyces pombe [PDF]
The Schizosaccharomyces pombe Cdc4 protein is required for the formation and function of the contractile ring, presumably acting as a myosin light chain. By using NMR spectroscopy, we demonstrate that purified Cdc4p is a monomeric protein with two structurally independent domains, each exhibiting a fold reminiscent of the EF-hand class of calcium ...
Terry Huebert+7 more
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Cloning and Characterization of the Kinesin-related Protein, Krp1p, in Schizosaccharomyces pombe
Kinesin have been cloned in many organisms. They played important roles in the transport of cell organelles, polarized growth, and secretion. We report here the identification of a kinesin-related protein in Schizosaccharomyces pombe, which was named kinesin-related protein (Krplp). The primer sequences were driven from the highly conserved area of the
Jae Wook, Jeong+6 more
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Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe [PDF]
In eukaryotes, chromosomal DNA is equally distributed to daughter cells during mitosis, whereas the number of chromosomes is halved during meiosis. Despite considerable progress in understanding the molecular mechanisms that regulate mitosis, there is ...
Barbara Sivakova+7 more
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Sequence of the cDNA for one acidic ribosomal protein ofSchizosaccharomyces pombe
Beltrame M., Bianchi M. E.
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Objective: Metformin, a well-known anti-diabetic drug and a caloric restriction mimetic, seems to attenuate aging through myriad cellular processes, wherein most of its mode of action is still elusive.
Çağatay Tarhan+2 more
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Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics. [PDF]
Schizosaccharomyces pombe is an outstanding model organism for cell biological investigations, yet the range of useful and well-characterized fluorescent proteins (XFPs) is limited.
Bassem Al-Sady+4 more
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Budding yeast Saccharomyces cerevisiae and fission yeast Schizosaccharomyces pombe are good models for heterochromatin study. In S. pombe, H3K9 methylation and Swi6, an ortholog of mammalian HP1, lead to heterochromatin formation. However, S.
Junsoo Oh+3 more
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Explaining lengths and shapes of yeast by scaling arguments. [PDF]
Lengths and shapes are approached in different ways in different fields: they serve as a read-out for classifying genes or proteins in cell biology whereas they result from scaling arguments in condensed matter physics.
Daniel Riveline
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