The Multiple Functions of Rho GTPases in Fission Yeasts
Cells, 2021 The Rho family of GTPases represents highly conserved molecular switches involved in a plethora of physiological processes. Fission yeast Schizosaccharomyces pombe has become a fundamental model organism to study the functions of Rho GTPases over the ...
Jero Vicente-Soler +4 more
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Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]
, 2006 In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad +102 more
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mBio, 2016 Proteins containing polyglutamine (polyQ) regions are found in almost all eukaryotes, albeit with various frequencies. In humans, proteins such as huntingtin (Htt) with abnormally expanded polyQ regions cause neurodegenerative diseases such as Huntington’
Ashley A. Zurawel +8 more
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Tpr1, a Schizosaccharomyces pombe protein involved in potassium transport [PDF]
FEBS Letters, 1999 The Schizosaccharomyces pombe Tpr1 was isolated as suppressor of the Saccharomyces cerevisiae Δ trk1,2 potassium uptake deficient phenotype. Tpr1, for tetratrico peptide repeat, encodes a 1039 amino acid residues protein with several reiterated TPR units displaying significant homology to p150TSP, a recently identified phosphoprotein of mouse, to S ...
Lichtenberg, H, Heyer, M, Höfer, M
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Rad62 protein functionally and physically associates with the Smc5/Smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast [PDF]
, 2004 Smc5 and Smc6 proteins form a heterodimeric SMC (structural maintenance of chromosome) protein complex like SMC1-SMC3 cohesin and SMC2-SMC4 condensin, and they associate with non-SMC proteins Nse1 and Nse2 stably and Rad60 transiently.
Carr, Antony +5 more
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BMC Research Notes, 2019 Objectives The fission yeast Schizosaccharomyces pombe is predicted to encode ~ 200 proteins of
Sophie Longmuir +2 more
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Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2012 The ERH gene encodes a highly conserved small nuclear protein with a unique amino acid sequence and three-dimensional structure but unknown function. The gene is present in animals, plants, and protists but to date has only been found in few fungi.
Marek K Krzyzanowski +2 more
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High level constitutive expression of luciferase reporter by lsd90 promoter in fission yeast. [PDF]
PLoS ONE, 2014 Because of a large number of molecular similarities with higher eukaryotes, the fission yeast Schizosaccharomyces pombe has been considered a potentially ideal host for expressing human proteins having therapeutic and pharmaceutical applications. However,
Hemant Kumar Verma +6 more
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DNA-protein interactions at the telomeric repeats of Schizosaccharomyces pombe [PDF]
Nucleic Acids Research, 1996 Gel retardation assays using a probe containing the repeat region of a Schizosaccharomyces pombe chromosomal telomere identified four specific DNA- protein complexes in S. pombe total protein extracts (I, I', IIa and IIb). The proteins responsible for these complexes bound to the telomeric repeat region irrespective of whether or not the repeats were ...
M, Duffy, A, Chambers
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Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex [PDF]
, 2018 ELL family transcription factors activate the overall rate of RNA polymerase II (Pol II) transcription elongation by binding directly to Pol II and suppressing its tendency to pause.
Alonso-Nunez +54 more
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