PLoS ONE, 2021 In spite of increased complexity in eukaryotes compared to prokaryotes, several basic metabolic and regulatory processes are conserved. Here we explored analogies in the eubacteria Escherichia coli and the unicellular fission yeast Schizosaccharomyces ...
Joivier Vichi +7 more
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The Schizosaccharomyces pombe Hsp104 disaggregase is unable to propagate the [PSI] prion. [PDF]
PLoS ONE, 2009 The molecular chaperone Hsp104 is a crucial factor in the acquisition of thermotolerance in yeast. Under stress conditions, the disaggregase activity of Hsp104 facilitates the reactivation of misfolded proteins. Hsp104 is also involved in the propagation
Patrick Sénéchal +4 more
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The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2011 The ubiquitin-like protein NEDD8 is highly conserved in eukaryotes, from man to Schizosaccharomyces pombe. NEDD8 conjugation to cullin proteins is a prerequisite for cullin based E3 ubiquitin ligase activity, and essential for S. pombe viability.
David Girdwood +2 more
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mBio, 2016 Proteins containing polyglutamine (polyQ) regions are found in almost all eukaryotes, albeit with various frequencies. In humans, proteins such as huntingtin (Htt) with abnormally expanded polyQ regions cause neurodegenerative diseases such as Huntington’
Ashley A. Zurawel +8 more
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Characterization of Glycoside Hydrolase Family 5 Proteins in Schizosaccharomyces pombe [PDF]
Eukaryotic Cell, 2010 ABSTRACT In yeast, enzymes with β-glucanase activity are thought to be necessary in morphogenetic events that require controlled hydrolysis of the cell wall. Comparison of the sequence of the Saccharomyces cerevisiae exo-β(1,3)-glucanase Exg1 with the Schizosaccharomyces pombe ...
Jean-Paul Latgé +5 more
openaire +4 more sources
High level constitutive expression of luciferase reporter by lsd90 promoter in fission yeast. [PDF]
PLoS ONE, 2014 Because of a large number of molecular similarities with higher eukaryotes, the fission yeast Schizosaccharomyces pombe has been considered a potentially ideal host for expressing human proteins having therapeutic and pharmaceutical applications. However,
Hemant Kumar Verma +6 more
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The Multiple Functions of Rho GTPases in Fission Yeasts
Cells, 2021 The Rho family of GTPases represents highly conserved molecular switches involved in a plethora of physiological processes. Fission yeast Schizosaccharomyces pombe has become a fundamental model organism to study the functions of Rho GTPases over the ...
Jero Vicente-Soler +4 more
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Regulation of Ace2-dependent genes requires components of the PBF complex in schizosaccharomyces pombe [PDF]
, 2015 The division cycle of unicellular yeasts is completed with the activation of a cell separation program that results in the dissolution of the septum assembled during cytokinesis between the 2 daughter cells, allowing them to become independent entities ...
Alonso-Nuñez, María Luisa +4 more
core +1 more source
Role of Schizosaccharomyces pombe RecQ homolog recombination and checkpoint genes in UV Damage tolerance [PDF]
, 1997 The cellular responses to DNA damage are complex and include direct DNA repair pathways that remove the damage and indirect damage responses which allow cells to survive DNA damage that has not been, or cannot be, removed.
Carr, A M +3 more
core +3 more sources
Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2012 The ERH gene encodes a highly conserved small nuclear protein with a unique amino acid sequence and three-dimensional structure but unknown function. The gene is present in animals, plants, and protists but to date has only been found in few fungi.
Marek K Krzyzanowski +2 more
doaj +1 more source