Objectives The fission yeast Schizosaccharomyces pombe is predicted to encode ~ 200 proteins of
Sophie Longmuir+2 more
doaj +1 more source
Rad62 protein functionally and physically associates with the Smc5/Smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast [PDF]
Smc5 and Smc6 proteins form a heterodimeric SMC (structural maintenance of chromosome) protein complex like SMC1-SMC3 cohesin and SMC2-SMC4 condensin, and they associate with non-SMC proteins Nse1 and Nse2 stably and Rad60 transiently.
Carr, Antony+5 more
core +2 more sources
Why cells grow and divide? General growth mechanism and how it defines cells' growth, reproduction and metabolic properties [PDF]
We consider a general growth mechanism, which acts at cellular level and above (organs, systems and whole organisms). Using its mathematical representation, the growth equation, we study the growth and division mechanisms of amoeba and fission yeast Schizosaccharomyces pombe.
arxiv +1 more source
Formins Determine the Functional Properties of Actin Filaments in Yeast [PDF]
The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including ...
Balasubramanian+29 more
core +1 more source
Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe
Many meiosis-specific proteins in Schizosaccharomyces pombe contain coiled-coil motifs which play essential roles for meiotic progression. For example, the coiled-coil motifs present in Meu13 and Mcp7 are required for their function as a putative ...
Okuzaki Daisuke+3 more
doaj +1 more source
Suppression of sensitivity to drugs and antibiotics by high external cation concentrations in fission yeast. [PDF]
Potassium ion homeostasis plays an important role in regulating membrane potential and therefore resistance to cations, antibiotics and chemotherapeutic agents in Schizosaccharomyces pombe and other yeasts.
John P Alao+3 more
doaj +1 more source
Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex [PDF]
ELL family transcription factors activate the overall rate of RNA polymerase II (Pol II) transcription elongation by binding directly to Pol II and suppressing its tendency to pause.
Alonso-Nunez+54 more
core +1 more source
Mutational Analysis of Cdc19p, a Schizosaccharomyces pombe MCM Protein [PDF]
The cdc19 + gene encodes an essential member of the MCM family of replication proteins in Schizosaccharomyces pombe. We have examined the structure and function of the Cdc19p protein using molecular and genetic approaches. We find that overproduction of wild-type Cdc19p in wild-type cells has no effect, but cdc19-P1 mutant cells do not tolerate ...
Sabine Ottilie+4 more
openaire +3 more sources
Over the years, genetic profiling of the gut microbiome of patients with colorectal cancer (CRC) using genome sequencing has suggested over-representation of several bacterial taxa. However, little is known about the protein or metabolite secretions from
Siok-Fong Chin+3 more
doaj +1 more source
Schizosaccharomyces pombe Homologs of Human DJ-1 Are Stationary Phase-Associated Proteins That Are Involved in Autophagy and Oxidative Stress Resistance. [PDF]
The Parkinson's disease protein DJ-1 is involved in various cellular functions including detoxification of dicarbonyl compounds, autophagy and oxidative stress response.
Yang Su+4 more
doaj +1 more source