Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe
Many meiosis-specific proteins in Schizosaccharomyces pombe contain coiled-coil motifs which play essential roles for meiotic progression. For example, the coiled-coil motifs present in Meu13 and Mcp7 are required for their function as a putative ...
Okuzaki Daisuke +3 more
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Mutational Analysis of Cdc19p, a Schizosaccharomyces pombe MCM Protein [PDF]
The cdc19 + gene encodes an essential member of the MCM family of replication proteins in Schizosaccharomyces pombe. We have examined the structure and function of the Cdc19p protein using molecular and genetic approaches. We find that overproduction of wild-type Cdc19p in wild-type cells has no effect, but cdc19-P1 mutant cells do not tolerate ...
S L, Forsburg +4 more
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Role of the Schizosaccharomyces pombe F-box DNA helicase in processing recombination intermediates. [PDF]
In an effort to identify novel genes involved in recombination repair, we isolated fission yeast Schizosaccharomyces pombe mutants sensitive to methyl methanesulfonate (MMS) and a synthetic lethal with rad2.
Carr, Antony M +6 more
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Over the years, genetic profiling of the gut microbiome of patients with colorectal cancer (CRC) using genome sequencing has suggested over-representation of several bacterial taxa. However, little is known about the protein or metabolite secretions from
Siok-Fong Chin +3 more
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Suppression of sensitivity to drugs and antibiotics by high external cation concentrations in fission yeast. [PDF]
Potassium ion homeostasis plays an important role in regulating membrane potential and therefore resistance to cations, antibiotics and chemotherapeutic agents in Schizosaccharomyces pombe and other yeasts.
John P Alao +3 more
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Characterization of Glycoside Hydrolase Family 5 Proteins in Schizosaccharomyces pombe [PDF]
ABSTRACT In yeast, enzymes with β-glucanase activity are thought to be necessary in morphogenetic events that require controlled hydrolysis of the cell wall. Comparison of the sequence of the Saccharomyces cerevisiae exo-β(1,3)-glucanase Exg1 with the Schizosaccharomyces pombe ...
Encarnación, Dueñas-Santero +5 more
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The role of Schizosaccharomyces pombe SUMO ligases in genome stability [PDF]
SUMOylation is a post-translational modification that affects a large number of proteins, many of which are nuclear. While the role of SUMOylation is beginning to be elucidated, it is clear that understanding the mechanisms that regulate the process is ...
A. Skilton +44 more
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Summary: Heterochromatin functions as a scaffold for factors responsible for gene silencing and chromosome segregation. Heterochromatin can be assembled by multiple pathways, including RNAi and RNA surveillance.
Si Young Lee +8 more
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Schizosaccharomyces pombe Homologs of Human DJ-1 Are Stationary Phase-Associated Proteins That Are Involved in Autophagy and Oxidative Stress Resistance. [PDF]
The Parkinson's disease protein DJ-1 is involved in various cellular functions including detoxification of dicarbonyl compounds, autophagy and oxidative stress response.
Yang Su +4 more
doaj +1 more source
Characterization of Schizosaccharomyces pombe Rad2 protein, a FEN-1 homolog [PDF]
FEN-1 proteins are a family of nucleases essential for lagging strand DNA synthesis. A gene with sequence similarity to FEN-1 protein-encoding genes, rad2 +, has been identified in Schizosaccharomyces pombe . We report the overexpression, purification, and character-ization of the putative S.pombe FEN-1 homolog, Rad2p.
J L, Alleva, P W, Doetsch
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