Results 1 to 10 of about 49,600 (309)
The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy [PDF]
Frontiers in Cellular Neuroscience, 2022 Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang +8 more
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Schwann-spheres derived from injured peripheral nerves in adult mice--their in vitro characterization and therapeutic potential. [PDF]
PLoS ONE, 2011 Multipotent somatic stem cells have been identified in various adult tissues. However, the stem/progenitor cells of the peripheral nerves have been isolated only from fetal tissues.
Takehiko Takagi +10 more
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Frontiers in Cellular Neuroscience, 2021 Embryonic Dissociated Dorsal Root Ganglia (DRG) cultures are often used to investigate the role of novel molecular pathways or drugs in Schwann cell development and myelination.
Venkat Krishnan Sundaram +7 more
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Biochemistry and Biophysics Reports, 2023 Bell's palsy is the most common form of facial nerve palsy. This study aimed to explore the pathogenesis of Bell's palsy by investigating the effect of cold-stimulated adipocyte supernatant on adhesion molecule expression in Schwann cell line.
Tiefeng Zhang +6 more
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Research progress on mechanism of Schwann cells promoting peripheral nerve regeneration [PDF]
Jichu yixue yu linchuang, 2022 Schwann cells (SCs) have a strong plasticity. After peripheral nerve injury, Schwann cells dedifferentiate into repair phenotype and dominate the repair process. C-Jun N-terminal kinase, mitogen activated protein kinase(MAPK) and other signaling pathways
YANG Yi-duo, GUO Hai-dong, SHAO Shui-jin, LIU Yu-pu
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Inhibition of Schwann Cell Pyroptosis Promotes Nerve Regeneration in Peripheral Nerve Injury in Rats
Mediators of Inflammation, 2023 Background. Peripheral nerve injury (PNI) is one of the most debilitating injuries, but therapies for PNI are still far from satisfactory. Pyroptosis, a recently identified form of cell death, has been demonstrated to participate in different diseases ...
Jiayi Wang +9 more
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Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis
Cell Reports, 2023 Summary: Schwann cells play critical roles in peripheral neuropathies; however, the regulatory mechanisms of their homeostasis remain largely unknown. Here, we show that nucleoporin Seh1, a component of nuclear pore complex, is important for Schwann cell
Mei Wu +19 more
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Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. [PDF]
PLoS ONE, 2010 The myelin sheaths that surround the thick axons of the peripheral nervous system are produced by the highly specialized Schwann cells. Differentiation of Schwann cells and myelination occur in discrete steps.
Juliane Bremer +5 more
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PLoS ONE, 2020 Transference of RNAs and ribosomes from Schwann cell-to-axon was demonstrated in normal and regenerating peripheral nerves. Previously, we have shown that RNAs transfer is dependent on F-actin cytoskeleton and Myosin Va.
Lucía Canclini +6 more
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Molecular Medicine, 2021 Background Growth factors execute essential biological functions and affect various physiological and pathological processes, including peripheral nerve repair and regeneration.
Yaxian Wang +7 more
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