Results 161 to 170 of about 102,370 (356)

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi, Takeshi Osonoi, Norio Takahashi, Toru Takiguchi, Eiichiro Morishima, Yoshimasa Aso, Kenji Sekiguchi, Hideki Kamiya, Jiro Nakamura   +8 more
wiley   +1 more source

Impact of glycemic variability on early detection of sudomotor dysfunction: Implications for early intervention and personalized treatment

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background This study investigates the impact of glycemic variability on sudomotor dysfunction in type 2 diabetes mellitus. Methods A total of 206 type 2 diabetes mellitus patients and 34 healthy controls were included. Sweat function (SF) was assessed using electrochemical conductance of hands (HESC) and feet (FESC).
Yang Ou, Xiao‐feng Hu, Zhi Liang, Xiao‐hui Zhang, Yi‐kun Zhou   +4 more
wiley   +1 more source

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor, Rena E. Mullally, Sarah F. McComish, Julia O'Sullivan, Ian Woods, Ingmar Schoen, Massimiliano Garre, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +9 more
wiley   +1 more source

Author response: TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells

, 2021
Kae-Jiun Chang, Ira Agrawal, Anna Vainshtein, Wan Yun Ho, Wendy Xin, Greg Tucker‐Kellogg, Keiichiro Susuki, Elior Peles, Shuo‐Chien Ling, Jonah R. Chan   +9 more
openalex   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Electroacupuncture and moxibustion promote regeneration of injured sciatic nerve through Schwann cell proliferation and nerve growth factor secretion

, 2018
Shui-jin Shao, Hai-dong Guo, Lin-na Hu, Jin-xin Tian, Wei Gao, Jing Zhu, Fang-fang Mou, Xiao-chun Ye, Yu-pu Liu, Pingping Lu   +9 more
openalex   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Terminal Schwann cells at the human neuromuscular junction [PDF]

, 2021
Abrar Alhindi, Ines Boehm, Rachael O. Forsythe, J. D. Miller, Richard J. E. Skipworth, Hamish Simpson, Ross A. Jones, Thomas H. Gillingwater   +7 more
openalex   +1 more source

Schwann Cell [PDF]

, 2020
openaire   +1 more source

Clinical, Cytologic, Histopathologic, and Diagnostic Imaging of a Malignant Peripheral Nerve Sheath Tumor in the Renal Pelvis of a Border Collie Dog

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 12‐year‐old female spayed Border Collie dog was presented for evaluation of 6 months of intermittent hematuria and weight loss. A highly vascularized right renal mass deforming the renal architecture and paraneoplastic hypertrophic osteopathy were found. Cytologic evaluation of the mass obtained by fine‐needle aspiration guided by ultrasound
Félix Romero‐Vélez, Bárbara Serrano, Javier Martínez‐Caro, Sonia González‐Rellán, Rosa Novellas, Alicia García‐Ferrer, Josep Pastor, Laia Solano‐Gallego   +7 more
wiley   +1 more source