Results 11 to 20 of about 102,370 (356)
Research progress on mechanism of Schwann cells promoting peripheral nerve regeneration [PDF]
Jichu yixue yu linchuang, 2022 Schwann cells (SCs) have a strong plasticity. After peripheral nerve injury, Schwann cells dedifferentiate into repair phenotype and dominate the repair process. C-Jun N-terminal kinase, mitogen activated protein kinase(MAPK) and other signaling pathways
YANG Yi-duo, GUO Hai-dong, SHAO Shui-jin, LIU Yu-pu
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Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis
Cell Reports, 2023 Summary: Schwann cells play critical roles in peripheral neuropathies; however, the regulatory mechanisms of their homeostasis remain largely unknown. Here, we show that nucleoporin Seh1, a component of nuclear pore complex, is important for Schwann cell
Mei Wu +19 more
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PLoS ONE, 2021 Introduction Polyneuropathy is a debilitating condition characterized by distal sensory and motor deficits. Schwann cell dysfunction and axonal loss are integral factors in pathophysiology and disease progression of polyneuropathy.
Eva Placheta-Györi +4 more
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Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. [PDF]
PLoS ONE, 2010 The myelin sheaths that surround the thick axons of the peripheral nervous system are produced by the highly specialized Schwann cells. Differentiation of Schwann cells and myelination occur in discrete steps.
Juliane Bremer +5 more
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PLoS ONE, 2020 Transference of RNAs and ribosomes from Schwann cell-to-axon was demonstrated in normal and regenerating peripheral nerves. Previously, we have shown that RNAs transfer is dependent on F-actin cytoskeleton and Myosin Va.
Lucía Canclini +6 more
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Molecular Medicine, 2021 Background Growth factors execute essential biological functions and affect various physiological and pathological processes, including peripheral nerve repair and regeneration.
Yaxian Wang +7 more
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Dabrafenib Promotes Schwann Cell Differentiation by Inhibition of the MEK-ERK Pathway
Molecules, 2021 Schwann cell differentiation involves a dynamic interaction of signaling cascades. However, much remains to be elucidated regarding the function of signaling molecules that differ depending on the context in which the molecules are engaged.
Kyuhee Park +4 more
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Schwann Cell Myelination [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Myelinated nerve fibers are essential for the rapid propagation of action potentials by saltatory conduction. They form as the result of reciprocal interactions between axons and Schwann cells. Extrinsic signals from the axon, and the extracellular matrix, drive Schwann cells to adopt a myelinating fate, whereas myelination reorganizes the axon for its
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Integrative study of Arabidopsis thaliana metabolomic and transcriptomic data with the interactive MarVis-Graph software [PDF]
PeerJ, 2014 State of the art high-throughput technologies allow comprehensive experimental studies of organism metabolism and induce the need for a convenient presentation of large heterogeneous datasets.
Manuel Landesfeind +6 more
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Ribosomal trafficking is reduced in Schwann cells following induction of myelination. [PDF]
, 2015 Local synthesis of proteins within the Schwann cell periphery is extremely important for efficient process extension and myelination, when cells undergo dramatic changes in polarity and geometry.
Love, James M, Shah, Sameer B
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