Results 191 to 200 of about 49,600 (309)

P2-purigenic receptors regulate phospholipase C and adenylate cyclase activities in immortalized Schwann cells [PDF]

, 1996
Liliana N. Berti‐Mattera, Pamela L. Wilkins, Zuhayr T. Madhun, Deborah Suchovsky   +3 more
openalex   +1 more source

Selumetinib Treatment in a Neurofibromatosis Type 1 Child With Second Hit Mutation on the NF1 Gene

International Journal of Developmental Neuroscience, Volume 85, Issue 6, October 2025.
Initial germline NF1 splice‐site mutation c.3113 + 1G > A followed by tumour‐specific somatic second‐hit mutation c.2033dup (p.Ile679Aspfs*21) exemplifies Knudson's two‐hit hypothesis, driving uncontrolled cell proliferation. ABSTRACT Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder, with plexiform neurofibromas occurring in ...
Song Su, Yuexia Bai, Yi Lu, Ying Ren, Wenchao Zhang, Guangyu Wang, Kai Ma, Hongwei Zhang   +7 more
wiley   +1 more source

Unveiling the Role of Schwann Cell Plasticity in the Pathogenesis of Diabetic Peripheral Neuropathy. [PDF]

Int J Mol Sci
Abd Razak NH, Idris J, Hassan NH, Zaini F, Muhamad N, Daud MF.   +5 more
europepmc   +1 more source

Schwann cells transplanted in the lateral ventricles prevent the functional and anatomical effects of monocular deprivation in the rat.

, 1994
Tommaso Pizzorusso, Michela Fagiolini, Martina Fabris, G. Ferrari, L. Maffei   +4 more
openalex   +1 more source

Prosaptide activates the MAPK pathway by a G‐protein‐dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells [PDF]

, 1998
W. Marie Campana, Masao Hiraiwa, John S. O’Brien   +2 more
openalex   +1 more source

Spontaneous Malignant Peripheral Nerve Sheath Tumour in a Captive Rhesus Macaque (Macaca mulatta)

Journal of Medical Primatology, Volume 54, Issue 5, October 2025.
ABSTRACT Spontaneous peripheral nerve sheath tumors (PNSTs) are rare and often benign neoplasms in veterinary species and humans. This report describes the clinical, gross, histopathological, and immunological findings of a spontaneous malignant PNST embedded deep within the soft tissue in the forearm of a 4‐year‐old captive male rhesus macaque (Macaca
Marietta V. Barro, Jacob D. Herford, Laura M. Garzel, Peter Chu, J. Rachel Reader   +4 more
wiley   +1 more source

Role of the Egr2 Promoter Antisense RNA in Modulating the Schwann Cell Chromatin Landscape. [PDF]

Biomedicines
Martinez Moreno M, Karambizi D, Hwang H, Fregoso K, Michles MJ, Fajardo E, Fiser A, Tapinos N.   +7 more
europepmc   +1 more source

Functional Gap Junctions in the Schwann Cell Myelin Sheath [PDF]

, 1998
Rita J. Balice‐Gordon, Linda Jo Bone, Steven S. Scherer   +2 more
openalex   +1 more source

The Spectrum of Neurologic Phenotypes Associated With NUS1 Pathogenic Variants: A Comprehensive Case Series

Annals of Neurology, Volume 98, Issue 3, Page 561-572, September 2025.
Objective A growing body of evidence indicates a strong genetic overlap between developmental and epileptic encephalopathies (DEEs) and movement disorders. De novo loss‐of‐function variants in NUS1 have been recently identified in DEE cases. Herein, we report a large cohort of cases with pathogenic NUS1 variants and describe their clinical presentation
Sarah M. Brooker, Maria Novelli, Robert Coukos, Neha Prakash, Walaa A. Kamel, Marta Amengual‐Gual, Mathieu Anheim, Giulia Barcia, Tanya Bardakjian, Franciska Baur, Steffen Berweck, Bigna K. Bölsterli, Melanie Brugger, Thomas Cassini, Nicolas Chatron, Brian Corner, Hormos Salimi Dafsari, Jean‐Madeleine de Sainte Agathe, Colin A. Ellis, Kimberly M. Ezell, Cendrine Foucard, Steven J. Frucht, Maria C. Garcia, Deepak Gill, Anne Guimier, Rizwan Hamid, Damià Heine‐Suñer, Peter Herkenrath, Marie Hully, Ioannis U. Isaias, Louis Januel, Chloe Laurencin, Taylor Laut, Alinoe Lavillaureix, Gaetan Lesca, Marion Lesieur‐Sebellin, Luca Magistrelli, Cecilia Marelli, Heather C. Mefford, Bryce A. Mendelsohn, Saadet Mercimek‐Andrews, Claire Miller, Shekeeb S. Mohammad, Francesca Morgante, Sirisha Nandipati, Thomas Opladen, Mahesh Padmanaban, Micaela Pauni, Gianni Pezzoli, Amelie Piton, Francis Ramond, Giulietta M. Riboldi, Christelle Rougeot‐Jung, Fernando Santos‐Simarro, Ingrid E. Scheffer, Naoual Serari, Christine M. Stahl, Ann Stembridge Kung, Susana Tarongí Sanchez, Christel Thauvin‐Robinet, Marianne Till, Christine Tranchant, Christopher Troedson, Thomas F. Tropea, Olivier Vanakker, Patricia Vega, Maxi Leona Wiese, Udo Wieshmann, Laura J. Williams, Thomas Wirth, Michael Zech, Hans Zempel, Emmanuel Roze, Vincenzo Leuzzi, Serena Galosi, Victor S. C. Fung, Gemma Carvill, Dimitri Krainc, Elizabeth Gerard, Niccolò E. Mencacci   +79 more
wiley   +1 more source

Immortalized Schwann cell lines as useful tools for pathogenesis-based therapeutic approaches to diabetic peripheral neuropathy. [PDF]

Front Endocrinol (Lausanne)
Sango K, Yako H, Niimi N, Takaku S.
europepmc   +1 more source