Results 1 to 10 of about 51,731 (281)
Schwann cells in regeneration and cancer [PDF]
Frontiers in PharmacologySchwann cells are specific peripheral glial cells with remarkable plasticity following peripheral nerve injury. Injury responses stimulate c-Jun activation in Schwann cells, drive epithelial-mesenchymal transition and cellular phenotypic changes, and ...
Lan Zhang +4 more
doaj +4 more sources
The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy [PDF]
Frontiers in Cellular Neuroscience, 2022 Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang +8 more
doaj +3 more sources
TRPV4 activation in Schwann cells mediates mechanically induced pain of oral cancer [PDF]
Frontiers in Pain ResearchIntroductionPatients with oral cancer often experience intense functional pain due to mechanical stimulation at the cancer site. The role of mechanosensitive ion channels in oral cancer pain, such as TRPV4, is not fully understood.ObjectivesOur objective
Yatendra Mulpuri +26 more
doaj +2 more sources
Pharmacologically targeting Schwann cells to improve regeneration following nerve damage [PDF]
Frontiers in Cell and Developmental BiologySchwann cells provide essential support for nerve growth and survival following peripheral nerve damage by producing various growth factors and other signalling molecules.
Alaa A. Alhamdi +7 more
doaj +2 more sources
The formation of lipid droplets favors intracellular Mycobacterium leprae survival in SW-10, non-myelinating Schwann cells. [PDF]
PLoS Neglected Tropical Diseases, 2017 Leprosy is a chronic infectious disease that is caused by the obligate intracellular pathogen Mycobacterium leprae (M.leprae), which is the leading cause of all non-traumatic peripheral neuropathies worldwide.
Song-Hyo Jin +2 more
doaj +1 more source
Schwann-spheres derived from injured peripheral nerves in adult mice--their in vitro characterization and therapeutic potential. [PDF]
PLoS ONE, 2011 Multipotent somatic stem cells have been identified in various adult tissues. However, the stem/progenitor cells of the peripheral nerves have been isolated only from fetal tissues.
Takehiko Takagi +10 more
doaj +1 more source
Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro
Stem Cells International, 2022 Schwann cells have been found to promote osteogenesis by an unclear molecular mechanism. To better understand how Schwann cells accelerate osteogenesis, RNA-Seq and LC-MS/MS were utilized to explore the transcriptomic and metabolic response of MC3T3-E1 ...
Jun-Qin Li +10 more
doaj +1 more source
Neural Regeneration Research, 2023 Studies have shown that human hair keratin (HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secrete nerve growth factor, which ...
Han-Jun Qin +7 more
doaj +1 more source
Journal of Experimental & Clinical Cancer Research, 2022 Background Research has indicated that the emergence of Schwann cells around premalignant lesions of colon cancer might be an early indicator promoting the onset of tumorigenesis.
Shengbo Han +13 more
doaj +1 more source
FGF5 Regulates Schwann Cell Migration and Adhesion
Frontiers in Cellular Neuroscience, 2020 The fibroblast growth factor (FGF) family polypeptides play key roles in promoting tissue regeneration and repair. FGF5 is strongly up-regulated in Schwann cells of the peripheral nervous system following injury; however, a role for FGF5 in peripheral ...
Bing Chen +7 more
doaj +1 more source