P2-purigenic receptors regulate phospholipase C and adenylate cyclase activities in immortalized Schwann cells [PDF]
Liliana N. Berti‐Mattera+3 more
openalex +1 more source
Postoperative adhesions are a common complication following surgical intervention, typically forming between the surfaces of soft tissues within body cavities. Hydrogels demonstrate significant anti‐adhesion and tissue regeneration effects through multiple mechanisms, offering new perspectives and potential strategies for effectively preventing ...
Ting Wang+8 more
wiley +1 more source
Schwann Cells in Neuromuscular Disorders: A Spotlight on Amyotrophic Lateral Sclerosis. [PDF]
Moss KR, Saxena S.
europepmc +1 more source
Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2.
Thomas K. Morrissey+4 more
openalex +1 more source
Abstract Keloids are scars that grow abnormally due to excessive extracellular matrix production by fibroblasts and increased angiogenesis. Chronic tension is implicated in their growth, but the exact pathology remains unclear. This study investigated the increased expression of molecules responsible for sensing pressure in keloids compared with ...
Shinsuke Akita+15 more
wiley +1 more source
Cannabinoid receptor 2 facilitates the Schwann cells-dependent peripheral nerve regeneration. [PDF]
Xu H+6 more
europepmc +1 more source
Evaluation of TRPA1 as a Therapeutic Target in MYCN‐Amplified Neuroblastoma
ABSTRACT Background Neuroblastoma (NB) is a childhood cancer with a high relapse rate despite intensive treatment. TRPA1 is a pain‐sensing ion channel with downstream impacts on proliferative and pro‐apoptotic pathways. Here, we evaluated TRPA1 expression in NB and performed pharmacological inhibition in preclinical models to assess its potential as a ...
Alexandra Seger+13 more
wiley +1 more source
The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells. [PDF]
Weaver MR+14 more
europepmc +1 more source
Conductive Nerve Conduits With Orientated Topological Structures From Ice‐Templating Technology
Conductive nerve conduits featuring oriented topological structures are engineered through ice‐templating technology, utilizing hydrogels and temperature gradients. Such conduits enhance peripheral nerve regeneration by integrating conductivity, aligned architecture, and growth factors, as demonstrated by improved motor recovery in rat models with ...
Hui Zhang+6 more
wiley +1 more source
PEX11B palmitoylation couples peroxisomal dysfunction with Schwann cells fail in diabetic neuropathy. [PDF]
Yang YM, Ma HB, Xiong Y, Wu Q, Gao XK.
europepmc +1 more source