Results 101 to 110 of about 3,294 (199)

Synthesis of lipophosphoramidyl-cyclodextrins and their supramolecular properties

, 2012
International audienceThe synthesis of lipophosphoramidyl-β-CD was obtained by an Atherton–Todd (AT) reaction that involved dioleylphosphite and either functionalized permethylated or native β-cyclodextrin.
Florence Djedaïni-Pilard, Fréderic Aubry, Wattraint, Olivier, Sarazin, Catherine, Aubry, Fréderic, Paul-Alain Jaffrès, Gervaise, Cedric, Bonnet, Véronique, Catherine Sarazin, Véronique Bonnet, Jaffres, Paul-Alain, Olivier Wattraint, Cédric Gervaise, Djedaïni-Pilard, Florence   +13 more
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Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions

, 2018
Hyoscyamine 6β-hydroxylase (H6H) is an α-ketoglutarate dependent mononuclear nonheme iron enzyme that catalyzes C6-hydroxylation of hyoscyamine and oxidative cyclization of the resulting product to give the oxirane natural product scopolamine.
Hung-wen Liu (1279131), Yung-nan Liu (1952272), Mark W. Ruszczycky (1575478), Feng Yan (183226), Richiro Ushimaru (1674505), Wei-chen Chang (1530808)   +5 more
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Filmes de acetato de celulose/poli (caprolactona triol): diagrama de fases, propriedades térmicas, mecânicas e controle da permeação de um fármaco modelo [PDF]

, 2004
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Quimica.Neste trabalho, foi abordada a preparação de filmes de acetato de celulose (AC) com porosidade controlada, tendo ...
Meier, Marcia Margarete
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Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-tioacetate derivatives

, 2014
Seven new compounds have been synthetized in satisfactory yields (51-78 %), through the treatment of mesoionic 1,3-thiazolium-5-thiolate (4a-d) and 1,3,4-thiadiazolium-5-thiolate (10a,b) with chloroacetic acid or methyl iodide: 1,3-thiazolium-5 ...
LIRA, BRUNO F., MENDONÇA JUNIOR, FRANCISCO J. B., SCOTTI, LUCIANA, JOSÉ A. S. LUIS, THIAGO M. DE AQUINO, FRANCISCO J. B. MENDONÇA JUNIOR, SCOTTI, MARCUS T., PETRÔNIO F. A. FILHO, LUIS, JOSÉ A. S., BRUNO F. LIRA, MARCUS T. SCOTTI, FILHO, PETRÔNIO F. A., DE AQUINO, THIAGO M., LUCIANA SCOTTI   +13 more
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Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer’s Disease Agents

, 2018
Multifunctional agents aiming at cholinesterases (ChEs) and monoamine oxidases (MAOs) are promising therapy for Alzheimer’s disease (AD). Herein, a series of novel propargylamine-modified pyrimidinylthiourea derivatives (1–4) were designed and ...
Fei Mao, Jin Zhu, Xiaokang Li, Fei Mao (7777), Huan Wang (109286), Wenwen Liu, Wenwen Liu (195246), Jin Zhu (164147), Yixiang Xu (675419), Jian Zhang (1682), Huan Wang, Keting Bao, Jian Li, Jian Zhang, Xiaokang Li (158714), Keting Bao (4581799), Haiyan Zhang, Jian Li (41607), Haiyan Zhang (176919), Yixiang Xu   +19 more
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Therapeutic potential of selanyl amide derivatives in the in vitro anticholinesterase activity and in in vivo anti-amnesic action

, 2019
The present study evaluated the in vitro acetylcholinesterase (AChE) inhibitor activity of two new selanyl amide derivatives in cerebral structures of mice. Our results demonstrated that N-(2-(3-(phenylselanyl)propoxy)phenyl)furan-2-carboxamide (1) and N-
Wilhelm, Ethel A, Pereira, Caroline F, Vogt, Ane G, dos Santos, Brenda G. T., Cargnelutti, Roberta, Luchese, Cristiane, Cervo, Rodrigo, Torres, Marina Laura C. P.   +7 more
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Rg3강화 인삼추출물의 scopolamine으로 유도되는 인지능력 저하 억제효능

, 2012
학위논문 (석사)-- 서울대학교 대학원 : 농생명공학부(바이오모듈레이션전공), 2012. 2. 이형주.인삼은 전통적으로 동양의학에서 많이 쓰여 온 약초이다. 그 중 진세노사이드는 당을 포함하는 트라이터핀 계열의 유도체로서 인삼의 주요활성물질로 알려져 있다. 한편 진세노사이드 Rg3는 인삼이 가지는 신경보호활성을 가지는 것으로 보고되었다.
심재성
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Integrative Multi-Omics Analysis Reveals the Immunoregulatory Effects of Sepia Ink on ADHD-like Phenotypes. [PDF]

Curr Issues Mol Biol
Wei B, Yin J, Yuan W, Cai P, Song Q, Li Z, Ma X, Yang X, Hong L, Guan H, Du G, Yang W.   +11 more
europepmc   +1 more source

4-Chlorobenzylamine Containing Maleic Acid Derivatives: Synthesis, <i>In Silico</i> Studies, and Anti-Alzheimer's Activity. [PDF]

ACS Chem Neurosci
Tariq MJ, Kanwal M, Ata A, Nadeem H, Siddiqui M.   +4 more
europepmc   +1 more source

Exploring the Evolving Role of Scopolamine in Pharmacotherapy: From Cognitive Impairment to Neuroplasticity?-A Narrative Review. [PDF]

Molecules
Kukla J, Olejnik P, Kasarełło K.
europepmc   +1 more source