Results 91 to 100 of about 3,294 (199)

Pharmacological Management, Safety, and Outcomes in Bipolar Disorder: An Integrated Narrative Review of Clinical and Translational Evidence

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This graph summarizes bipolar disorder management, showing pharmacological treatments including lithium, valproate, antipsychotics, combination therapy, and emerging agents. It links these treatments to outcomes such as relapse reduction, mortality benefits, and cognitive effects, while highlighting safety issues, poor adherence, pregnancy risks, and ...
Gudisa Bereda
wiley   +1 more source

Prospective comparison of diagnostic accuracy of ultrasound, PET/CT and DW‐MRI for preoperative assessment of pelvic lymph nodes in cervical cancer patients: results of the CANNES trial

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 836-851, June 2026.
ABSTRACT Objective To determine whether ultrasound is non‐inferior to positron‐emission tomography/computed tomography (PET/CT) and diffusion‐weighted magnetic resonance imaging (DW‐MRI) in terms of overall diagnostic accuracy for the preoperative assessment of pelvic lymph‐node status in cervical cancer.
F. Frühauf, D. Fischerová, F. Moro, R. Kocián, V. Ptáčník, M. Wagnerová, L. Lambert, A. C. Testa, N. Bizzarri, R. O. Perez, E. Teodorico, D. Cibula, Collaborators, V. Poonyakanok, C. Culcasi   +14 more
wiley   +1 more source

The Effectiveness of Non‐Steroidal Anti‐Inflammatory Drugs for Pain Relief During Outpatient Intrauterine Device Insertion: A Systematic Review and Meta‐Analysis

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Background Fear of procedural pain is a significant barrier to intrauterine device (IUD) uptake. Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used in IUD insertion for their analgesic and anti‐inflammatory properties; however, evidence for their effectiveness remains inconsistent.
Marita S. Bolic, Jack Ainsworth, Clare Heal, Natalie Drever   +3 more
wiley   +1 more source

6-methyluracil derivatives as bifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease [PDF]

, 2015
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Novel 6-methyluracil derivatives with ω-(substituted benzylethylamino)alkyl chains at the nitrogen atoms of the pyrimidine ring were designed and synthesized. The numbers of methylene groups in the alkyl
Semenov V., Mikhailov A., Petukhova E., Reznik V., Kharlamova A., Masson P., Saifina L., Petrov K., Zobov V., Nikolsky E., Lushchekina S., Podyachev S., Zueva I., Mukhamedyarov M., Minnekhanova O.   +14 more
core  

Impact of Computer‐Aided Detection on Endoscopist's Gaze‐Shift Distance During Colonoscopy: a Randomized Controlled Trial (With Video)

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1760-1767, June 2026.
CADe assistance did not significantly change the gaze‐shift distance overall, but it reduced gaze‐shift distance among CADe‐experienced endoscopists. CADe may be associated with reduced eye strain, depending on the endoscopist's CADe experience. ABSTRACT Background and Aim Computer‐aided detection (CADe) facilitates colorectal lesion detection, but it ...
Shun Ito, Fumiaki Ishibashi, Kosuke Okusa, Kentaro Mochida, Takao Tonishi, Eri Ozaki, Sho Suzuki   +6 more
wiley   +1 more source

Capillary electrophoresis for the analysis of tropane alkaloids: pharmaceutical and phytochemical applications

, 1998
Three capillary electrophoresis methods, using UV detection, were developed for the simultaneous determination of several tropane alkaloids, including atropine, scopolamine and synthetic derivatives.
L. Mateus, Cherkaoui, Samir, Christen, Philippe, Mateus, Lidia, S. Cherkaoui, Veuthey, Jean-Luc, P. Christen, J.-L. Veuthey   +7 more
core   +1 more source

Anticholinergic Medication Burden Scales: A Systematic Review

Journal of the American Geriatrics Society, Volume 74, Issue 6, Page 1771-1784, June 2026.
ABSTRACT Background Anticholinergic burden refers to the cumulative anticholinergic effect of all medications taken by an individual. Anticholinergic burden scales help identify patients at risk of anticholinergic adverse effects and guide prescribing. However, substantial variation exists between scales, with no gold standard identified.
Orla Vennard, Carrie Stewart, Mansi Tolia, Roy L. Soiza, Phyo K. Myint   +4 more
wiley   +1 more source

Design and synthesis of 2-phenyl-1H-benzo[d]imidazole derivatives as 17β-HSD10 inhibitors for the treatment of Alzheimer's disease

It has been reported that 17β-HSD10 plays a key role in Alzheimer's disease. Here, a total of 44 2-phenyl-1H-benzo[d]imidazole derivatives were designed and synthesized as novel 17β-HSD10 inhibitors based on rational design and SAR studies.
Zhou, Bin, Shao, Chenwen, Lin, Jinyuan, Zhang, Xingxing, Ruan, Banfeng, Liu, Xiaohan, Qian, Yong, Chen, Yan, Chen, Liuzeng   +8 more
core   +1 more source

Tropane alkaloids in food

, 2010
A large number of wild and cultured plants produce secondary metabolites that are toxic to humans and animals. Through accidental or intentional mixing of these plants with normal food and feed the consumers of these products will be exposed to the ...
Adamse, P., Egmond, H.P., van
core  

6-methyluracil derivatives as bifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease

, 2020
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Novel 6-methyluracil derivatives with ω-(substituted benzylethylamino)alkyl chains at the nitrogen atoms of the pyrimidine ring were designed and synthesized. The numbers of methylene groups in the alkyl
Semenov V., Mikhailov A., Petukhova E., Reznik V., Kharlamova A., Masson P., Saifina L., Petrov K., Zobov V., Nikolsky E., Lushchekina S., Podyachev S., Zueva I., Mukhamedyarov M., Minnekhanova O.   +14 more
core