Results 11 to 20 of about 146,692 (204)

Diverse Structural Features of Potassium Channels Characterized by Scorpion Toxins as Molecular Probes

Molecules, 2019
Scorpion toxins are well-known as the largest potassium channel peptide blocker family. They have been successfully proven to be valuable molecular probes for structural research on diverse potassium channels. The potassium channel pore region, including
Yonghui Zhao, Zongyun Chen, Zhijian Cao, Wenxin Li, Yingliang Wu   +4 more
doaj   +2 more sources

Effect of scorpion toxin on the enterochromaffin-like cells in normal and Trypanosoma cruzi-infected rats: a morphological study [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1989
Intravenous injection of scorpion toxin (Tityus serrulatus) in normal and Trypanosoma cruzi infected rats did not cause ultrastructural morphologic changes on enterochromaffin-like (ECL) cells of the stomach, although it induced a significant increase of
N. H. Toppa, V. H. R. Leite, A. J. A. Barbosa, E. Chiari, H. M. S. Gonzaga, L. Freire-Maia, J. R. Cunha-Melo   +6 more
doaj   +2 more sources

Evaluation of the immunoprotective power of a multiple antigenic peptide against Aah II toxin of Androctonus australis hector scorpion

Vaccine: X
Scorpion envenoming (SE) is a public health problem in developing countries. In Algeria, the population exposed to the risk of SE was estimated at 86.45% in 2019.
Safouane M. Benazzouz, Nesrine Benlouahmia, Karima Bouhadida, Meriem Benlamara, Naziha Arezki, Oum El Kheir Sadeddine, Mourad Issad, Nabila Attal, Kamel Mansouri, Fawzi Derrar, Reda Djidjik   +10 more
doaj   +2 more sources

Inhibition of gastric emptying and intestinal transit in anesthetized rats by a Tityus serrulatus scorpion toxin

Brazilian Journal of Medical and Biological Research, 2000
The effects of a fraction (T1) of Tityus serrulatus scorpion venom prepared by gel filtration on gastric emptying and small intestinal transit were investigated in male Wistar rats.
L.E.A. Troncon, A.A. Santos, V.L. Garbacio, M. Secaf, A.V. Verceze, J.R. Cunha-Melo   +5 more
doaj   +2 more sources

The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening. [PDF]

PLoS ONE, 2015
We identified Tf2, the first β-scorpion toxin from the venom of the Brazilian scorpion Tityus fasciolatus. Tf2 is identical to Tb2-II found in Tityus bahiensis. We found that Tf2 selectively activates human (h)Nav1.3, a neuronal voltage-gated sodium (Nav)
Thalita S Camargos, Frank Bosmans, Frank Bosmans, Solange C Rego, Caroline B F Mourão, Elisabeth F Schwartz   +5 more
doaj   +3 more sources

Scorpion Alpha-Toxins Lqh-2☆

, 2009
In deep review of the pharmacology and toxicology of scorpion toxin Lqh2.
CATALDI, MAURO, Mauro Cataldi
openaire   +3 more sources

Scorpion-Toxins Lqh-3

, 2010
In deep review on the pharmacology and toxicology of scorpion toxin Lqh3.
CATALDI, MAURO, Mauro Cataldi
openaire   +4 more sources

Characterization of cDNA sequence encoding for a novel sodium channel -toxin from the Iranian scorpion Mesobuthus eupeus venom glands

Archives of Razi Institute, 2012
The venoms of Buthidae scorpions are known to contain basic, single-chain protein -toxins consisting of 60-70 amino acid residues that are tightly cross-linked by four disulfide bridges.
Eskandari, Gh.,, Jolodar, A., Ktsoyan, Z., Seyfiabad Shapouri, M.R.   +3 more
doaj   +1 more source

A bimodal activation mechanism underlies scorpion toxin-induced pain. [PDF]

Sci Adv, 2017
A scorpion toxin uses protons in the venom as coactivators to target nociceptive ion channel TRPV1 and cause pain.
Yang S, Yang F, Zhang B, Lee BH, Li B, Luo L, Zheng J, Lai R.   +7 more
europepmc   +2 more sources

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source