Results 91 to 100 of about 5,580 (197)

Scorpion Toxin, BmP01, Induces Pain by Targeting TRPV1 Channel

Toxins, 2015
The intense pain induced by scorpion sting is a frequent clinical manifestation. To date, there is no established protocol with significant efficacy to alleviate the pain induced by scorpion envenomation.
Md Abdul Hakim, Wenbin Jiang, Lei Luo, Bowen Li, Shilong Yang, Yuzhu Song, Ren Lai   +6 more
doaj   +1 more source

Design of antibody-reactive peptides from discontinuous parts of scorpion toxins.

, 2010
International audienceThe Amm VIII protein was previously isolated from the venom of the scorpion Androctonus mauretanicus mauretanicus. Despite 87% identity with AaH II, the most toxic alpha-type scorpion toxin, Amm VIII is not toxic to mice.
V. Moreau, Duarte, C., Nguyen, C., C. Duarte, Nguyen, Cong Tu, Martin-Eauclaire, M.-F., Granier, C., F. Molina, C. Chavez-Olortegui, Felicori, L., L. Felicori, Alvarenga, L., Chavez-Olortegui, C., C. Nguyen, M.-F. Martin-Eauclaire, Moreau, Violaine, Moreau, V., L. Alvarenga, Molina, F., C. Granier   +19 more
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Accurate prediction of scorpion toxin functional properties from primary structures

, 2005
Scorpion toxins are common experimental tools for studies of biochemical and pharmacological properties of ion channels. The number of functionally annotated scorpion toxins is steadily growing, but the number of identified toxin sequences is increasing ...
Koh, JLY, Tan, PTJ, Koh, J.L.Y., Tan, P.T.J., Seah, S.H., Brusic, V., Seah, SH, Ranganathan, S., Tan, TW, Brusic, V, Srinivasan, KN, Tan, T.W., Ranganathan, S, Srinivasan, K.N.   +13 more
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Pharmacological characterization of Kv1.3 inhibitor scorpion toxins [PDF]

, 2014
A Kv1.3 csatorna kulcsszerepet játszik az autoimmun megbetegedéseket kiváltó effektor memória T-sejtek (TEM) aktivációs mechanizmusában. A csatornán átfolyó K+ áram gátlásával a TEM sejtek aktivációja gátolható.
Bartók, Ádám
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Computational Simulations of Interactions of Scorpion Toxins with the Voltage-Gated Potassium Ion Channel

, 2004
Based on a homology model of the Kv1.3 potassium channel, the recognitions of the six scorpion toxins, viz. agitoxin2, charybdotoxin, kaliotoxin, margatoxin, noxiustoxin, and Pandinus toxin, to the human Kv1.3 potassium channel have been investigated by ...
Yu, Kunqian, Chen, Kai Xian, Luo, Xiaomin, Shen, Jianhua, Ding, Jianping, Liu, Hong, Fu, Wei, Jiang, Hualiang   +7 more
core   +1 more source

Characterization of Functional Effects of Two New Active Fractions Isolated From Scorpion Venom on Neuronal Ca2+ Spikes: A Possible Action on Ca2+-Dependent Dependent K+ Channels

Basic and Clinical Neuroscience, 2019
Introduction: It is a long time that natural toxin research is conducted to unlock the medical potential of toxins. Although venoms-toxins cause pathophysiological conditions, they may be effective to treat several diseases.
Hanieh Tamadon, Zahra Ghasemi, Fatemeh Ghasemi, Narges Hosseinmardi, Hossein Vatanpour, Mahyar Janahmadi   +5 more
doaj  

Target-specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates

, 2017
Scorpions use their venom in defensive situations as well as for subduing prey. Since some species of scorpion use their venom more in defensive situations than others, this may have led to selection for differences in effectiveness in defensive ...
Koch B., Vargas Muñoz, Leidy Johana, Van Der Meijden A., Van Der Valk T., Estrada-Gómez S.   +4 more
core   +1 more source

Evaluation of the immunoprotective power of a multiple antigenic peptide against Aah II toxin of Androctonus australis hector scorpion

Vaccine: X
Scorpion envenoming (SE) is a public health problem in developing countries. In Algeria, the population exposed to the risk of SE was estimated at 86.45% in 2019.
Safouane M. Benazzouz, Nesrine Benlouahmia, Karima Bouhadida, Meriem Benlamara, Naziha Arezki, Oum El Kheir Sadeddine, Mourad Issad, Nabila Attal, Kamel Mansouri, Fawzi Derrar, Reda Djidjik   +10 more
doaj   +1 more source

The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily.

, 2005
International audienceAnimal toxins are highly reticulated and structured polypeptides that adopt a limited number of folds. In scorpion species, the most represented fold is the alpha/beta scaffold in which an helical structure is connected to an ...
Mosbah, Amor, Beeton, Christine, Andreotti, Nicolas, Sabatier, Jean-Marc, Ferrat, Gilles, Darbon, Hervé, Mansuelle, Pascal, Carrega, Louis, de Waard, Michel   +8 more
core   +1 more source

Os possíveis mediadores envolvidos na gênese da hiperalgesia induzida pela administração do veneno bruto de Tityus serrulatus (Escorpião-amarelo) em patas de rato [PDF]

, 2000
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.Ocorre em torno 10 mil casos de acidentes por ano no Brasil, causados por escorpião amarelo, sendo que o sintoma mais expressivo do envenenamento relatado por ...
Nowacki, Luciana Cristina
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