Results 101 to 110 of about 9,314 (214)

Human Dorsal Root Ganglia Neuronal Cell Line to Study Nociceptive Signaling: A New Pipeline for Pain Therapy

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
The nociceptive properties of differentiated human HD10.6 cells were characterized by multiple approaches (A). Peripheral sensitization was induced within HD10.6 cells in response to an inflammatory cocktail (B), modeling nociceptors in a chronic pain state.
Sara A. Dochnal, Yixing Du, Daniella Bandari, Kaue Franco Malange, Jack Bryant, Julia Borges Paes Lemes, Abby Whitford, Anna R. Cliffe, Prashant Mali, Kim Dore, Yury I. Miller, Tony L. Yaksh   +11 more
wiley   +1 more source

Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion.

PLoS ONE, 2015
Australian scorpion venoms have been poorly studied, probably because they do not pose an evident threat to humans. In addition, the continent has other medically important venomous animals capable of causing serious health problems.
Karen Luna-Ramírez, Verónica Quintero-Hernández, Víctor Rivelino Juárez-González, Lourival D Possani   +3 more
doaj   +1 more source

Development of a gold nanoparticle-based novel diagnostic prototype for in vivo detection of Indian red scorpion (Mesobuthus tamulus) venom

Toxicon: X
Indian red scorpion Mesobuthus tamulus is responsible for substantial mortality in India and Sri Lanka; however, no specific diagnostic method is available to detect the venom of this scorpion in envenomed plasma or body fluid.
Upasana Puzari, Mojibur R. Khan, Ashis K. Mukherjee   +2 more
doaj   +1 more source

Toxines et Transferts ioniques [PDF]

, 2011
Collection Rencontres en Toxinologie, ISSN 1760-6004 ; http://sfet.asso.fr/international/images/stories/SFET/pdf/Ebook-RT19-2011-signets.pdfInternational ...
Barbier, Julien, Benoit, Evelyne, Gilles, Nicolas, Ladant, Daniel, Martin-Eauclaire, Marie-France, Mattei, César, Molgó, Jordi, Popoff, Michel R., Servent, Denis   +8 more
core  

Scorpion Toxin, BmP01, Induces Pain by Targeting TRPV1 Channel

Toxins, 2015
The intense pain induced by scorpion sting is a frequent clinical manifestation. To date, there is no established protocol with significant efficacy to alleviate the pain induced by scorpion envenomation.
Md Abdul Hakim, Wenbin Jiang, Lei Luo, Bowen Li, Shilong Yang, Yuzhu Song, Ren Lai   +6 more
doaj   +1 more source

Sequencing and comparative-bioinformatic analysis of chlorotoxin-like peptide from Iranian scorpion Mesobuthus eupeus [PDF]

, 2011
زمینه و هدف: در سال های اخیر نوروتوکسین های عقرب از لحاظ خواص دارویی و اثرات فیزیولوژیک مورد مطالعات زیادی قرار گرفته اند. یکی از این توکسین ها که توجه زیادی را به خود جلب کرده است، کلروتوکسین می باشد که هم اکنون در درمان سرطان های مغز مورد استفاده قرار ...
Ahadi, AliMohammad., Ayat, Hoda., Ilkhanizade, sheida., pirali kheirabadi, Khodadad.   +3 more
core   +1 more source

The scorpion toxin and the potassium channel

eLife, 2013
The structure of a complex containing a toxin bound to a potassium ion channel has been solved for the first time, revealing how scorpions have designed toxins that can recognize and target the filter that controls the movement of potassium ions through these channels.
openaire   +3 more sources

Characterization of Functional Effects of Two New Active Fractions Isolated From Scorpion Venom on Neuronal Ca2+ Spikes: A Possible Action on Ca2+-Dependent Dependent K+ Channels

Basic and Clinical Neuroscience, 2019
Introduction: It is a long time that natural toxin research is conducted to unlock the medical potential of toxins. Although venoms-toxins cause pathophysiological conditions, they may be effective to treat several diseases.
Hanieh Tamadon, Zahra Ghasemi, Fatemeh Ghasemi, Narges Hosseinmardi, Hossein Vatanpour, Mahyar Janahmadi   +5 more
doaj  

Evaluation of the immunoprotective power of a multiple antigenic peptide against Aah II toxin of Androctonus australis hector scorpion

Vaccine: X
Scorpion envenoming (SE) is a public health problem in developing countries. In Algeria, the population exposed to the risk of SE was estimated at 86.45% in 2019.
Safouane M. Benazzouz, Nesrine Benlouahmia, Karima Bouhadida, Meriem Benlamara, Naziha Arezki, Oum El Kheir Sadeddine, Mourad Issad, Nabila Attal, Kamel Mansouri, Fawzi Derrar, Reda Djidjik   +10 more
doaj   +1 more source

Structural Basis of the Selective Block of Kv1.2 by Maurotoxin from Computer Simulations

, 2015
The 34-residue polypeptide maurotoxin (MTx) isolated from scorpion venoms selectively inhibits the current of the voltage-gated potassium channel Kv1.2 by occluding the ion conduction pathway. Here using molecular dynamics simulation as a docking method,
Chen, Rong, Chung, Shin-Ho
core   +1 more source