Results 81 to 90 of about 5,580 (197)

Molecular divergence of two orthologous scorpion toxins affecting potassium channels

, 2011
Alpha-KTxs are a diverse group of scorpion short-chain peptide toxins that affect animal potassium channels. We report the biochemical purification, gene cloning, and functional characterization of a new alpha-KTx named MeuTx3B, from venom of the ...
Shunyi Zhu, Peigneur, Steve, Jan Tytgat, Dalziel, Julie, Zhu, Shunyi, Bin Gao, Steve Peigneur, Julie Dalziel, Gao, Bin, Tytgat, Jan   +9 more
core   +1 more source

Characterization of a Family of Scorpion Toxins Modulating Ca²⁺-Activated Cl^- Current in Vascular Myocytes. [PDF]

Toxins (Basel), 2022
Morel JL, Mokrzycki N, Lippens G, Drobecq H, Sautière P, Hugues M.   +5 more
europepmc   +1 more source

Venomics of Scorpion Ananteris platnicki (Lourenço, 1993), a New World Buthid That Inhabits Costa Rica and Panama

Toxins
Ananteris is a scorpion genus that inhabits dry and seasonal areas of South and Central America. It is located in a distinctive morpho-group of Buthids, the ‘Ananteris group’, which also includes species distributed in the Old World.
Cecilia Díaz, Bruno Lomonte, Arturo Chang-Castillo, Fabián Bonilla, Adriana Alfaro-Chinchilla, Felipe Triana, Diego Angulo, Julián Fernández, Mahmood Sasa   +8 more
doaj   +1 more source

Global transcriptome analysis of the scorpion Centruroides noxius: new toxin families and evolutionary insights from an ancestral scorpion species.

PLoS ONE, 2012
Scorpion venoms have been studied for decades, leading to the identification of hundreds of different toxins with medical and pharmacological implications.
Martha Rendón-Anaya, Luis Delaye, Lourival D Possani, Alfredo Herrera-Estrella   +3 more
doaj   +1 more source

The unfulfilled promises of scorpion insectotoxins

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Since the description and biochemical characterization of the first insect-specific neurotoxins from scorpion venoms, almost all contributions have highlighted their potential application as leads for the development of potent bioinsecticides.
Ernesto Ortiz, Lourival D Possani
doaj   +1 more source

Study of Anti-Inflammatory and Analgesic Activity of Scorpion Toxins DKK-SP1/2 from Scorpion Buthus martensii Karsch (BmK). [PDF]

Toxins (Basel), 2021
Liu Y, Li Y, Zhu Y, Zhang L, Ji J, Gui M, Li C, Song Y.   +7 more
europepmc   +1 more source

Binding modes and functional surface of anti-mammalian scorpion α-toxins to sodium channels

, 2016
Scorpion α-toxins bind to the voltage-sensing domains of voltage-gated sodium (NaV) channels and interfere with the inactivation mechanisms. The functional surface of α-toxins has been shown to contain an NC-domain consisting of the five-residue turn (
Chen, Rong, Chung, Shin-Ho
core   +1 more source

Development of a gold nanoparticle-based novel diagnostic prototype for in vivo detection of Indian red scorpion (Mesobuthus tamulus) venom

Toxicon: X
Indian red scorpion Mesobuthus tamulus is responsible for substantial mortality in India and Sri Lanka; however, no specific diagnostic method is available to detect the venom of this scorpion in envenomed plasma or body fluid.
Upasana Puzari, Mojibur R. Khan, Ashis K. Mukherjee   +2 more
doaj   +1 more source

Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion.

PLoS ONE, 2015
Australian scorpion venoms have been poorly studied, probably because they do not pose an evident threat to humans. In addition, the continent has other medically important venomous animals capable of causing serious health problems.
Karen Luna-Ramírez, Verónica Quintero-Hernández, Víctor Rivelino Juárez-González, Lourival D Possani   +3 more
doaj   +1 more source

Further enhancement of baculovirus insecticidal efficacy with scorpion toxins that interact cooperatively

, 2003
We have studied whether the cooperative insecticidal effect of certain scorpion toxin pairs, namely either a combination of excitatory and depressant, or alpha and depressant scorpion toxins, would improve the efficacy of Autographa californica ...
Gurevitz, Michael, Rivkin, Hadassah, Hadassah Rivkin, Regev, Avital, Eduard Gershburg, Nor Chejanovsky, Inceoglu, Bora, Gershburg, Eduard, Bora Inceoglu, Bruce D. Hammock, Avital Regev, Chejanovsky, Nor, Hammock, Bruce D., Michael Gurevitz   +13 more
core   +1 more source