Results 81 to 90 of about 9,314 (214)

Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion Centruroides limpidus (Karsch, 1879)

Toxins, 2019
Venom glands and soluble venom from the Mexican scorpion Centruroides limpidus (Karsch, 1879) were used for transcriptomic and proteomic analyses, respectively.
Jimena I. Cid-Uribe, Erika P. Meneses, Cesar V. F. Batista, Ernesto Ortiz, Lourival D. Possani   +4 more
doaj   +1 more source

Arizona bark scorpion venom resistance in the pallid bat, Antrozous pallidus. [PDF]

PLoS ONE, 2017
The pallid bat (Antrozous pallidus), a gleaning bat found in the western United States and Mexico, hunts a wide variety of ground-dwelling prey, including scorpions.
Bradley H Hopp, Ryan S Arvidson, Michael E Adams, Khaleel A Razak   +3 more
doaj   +1 more source

Impact of Comorbidities on Clinical Outcomes and Quality of Life of Patients With Hormone Receptor‐Positive/Human Epidermal Growth Factor Receptor 2‐Negative (HR+/HER2−) Advanced Breast Cancer Treated With Palbociclib in the POLARIS Study

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Background Comorbidities, common in patients with advanced breast cancer (ABC), may impact survival outcomes and health‐related quality of life (HRQoL). Here, we report subgroup analyses on the basis of comorbidities of patients from POLARIS (NCT03280303), a prospective, observational study of patients with hormone receptor‐positive/human ...
Debu Tripathy, Joanne L. Blum, Meghan S. Karuturi, Steven McCune, Sobha Kurian, Mehdi M. Moezi, Daniel M. Anderson, Yan Ji, Timothy J. Pluard, John Migas, Shailendra Lakhanpal, Erin Jepsen, Yao Wang, Monica Z. Montelongo, Zhe Zhang, Joseph C. Cappelleri, Eric Gauthier, Gabrielle B. Rocque   +17 more
wiley   +1 more source

Defensive Venoms: Is Pain Sufficient for Predator Deterrence?

Toxins, 2020
Pain, though unpleasant, is adaptive in calling an animal’s attention to potential tissue damage. A long list of animals representing diverse taxa possess venom-mediated, pain-inducing bites or stings that work by co-opting the pain-sensing pathways of ...
Crystal N. Niermann, Travis G. Tate, Amber L. Suto, Rolando Barajas, Hope A. White, Olivia D. Guswiler, Stephen M. Secor, Ashlee H. Rowe, Matthew P. Rowe   +8 more
doaj   +1 more source

Turning a Scorpion Toxin into an Antitumor Miniprotein [PDF]

Journal of the American Chemical Society, 2008
The oncoproteins MDM2 and MDMX negatively regulate the activity and stability of the tumor suppressor protein p53 and are important molecular targets for anticancer therapy. Grafting four residues of p53 critical for MDM2/MDMX binding to the N-terminal alpha-helix of BmBKTx1, a scorpion toxin isolated from the venom of the Asian scorpion Buthus ...
Chong, Li, Min, Liu, Juahdi, Monbo, Guozhang, Zou, Changqing, Li, Weirong, Yuan, Davide, Zella, Wei-Yue, Lu, Wuyuan, Lu   +8 more
openaire   +2 more sources

Dysphagia as the Sole Presentation of Lateral Medullary Syndrome in an Octagerian: A Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Lateral medullary syndrome (LMS) or Wallenberg's syndrome is usually caused by a cerebrovascular accident of the vertebral artery or the posterior inferior cerebellar artery (PICA), leading to damage to the dorsolateral aspects of the medulla oblongata.
Abera Kuma, Bereket A. Tegene, Sosena Sheleme, Shamil Nuri, Abdulkerim Girma, Sinetibeb Tadesse Amsalu   +5 more
wiley   +1 more source

EP80317 Restrains Inflammation and Mortality Caused by Scorpion Envenomation in Mice

Frontiers in Pharmacology, 2019
Over 1 million cases of scorpion stings are estimated every year, whereas current treatment is limited to antivenom serum combined with supportive therapy.
Karina F. Zoccal, Karina F. Zoccal, Luiz G. Gardinassi, Karla C. F. Bordon, Eliane C. Arantes, Sylvie Marleau, Huy Ong, Lúcia H. Faccioli   +7 more
doaj   +1 more source

Mass landscapes of seven scorpion species: the first analyses of Australian species with 1,5-DAN matrix [PDF]

, 2012
Scorpion venoms have been studied for over fifty years; however, the majority of research has focussed primarily on medically important Buthidae species. Additionally, venoms of the estimated 200 species of scorpion native to Australia have received very
Alewood, Paul F., Jones, Alun, Smith, Jennifer J.   +2 more
core  

Biogenic Synthesis of ZnO Nanoparticles From Heliotropium europaeum and Assessment of Antibiofilm, Anti‐Quorum‐Sensing, Antioxidant and Anticholinesterase Activities

Natural Sciences, Volume 6, Issue 2, April 2026.
Synthesis, characterization and biological activities of ZnO nanoparticles. ABSTRACT Zinc oxide nanoparticles (ZnO‐NPs) are inexpensive, non‐toxic, and biocompatible with human cells, making them suitable for biomedical applications. In the present study, ZnO‐NPs were synthesized from Heliotropium europaeum extracts at different concentrations through ...
Adel Manseur, Karima Hanini, Alfred Ngenge Tamfu, Louiza Boudiba, Busra Eroglu Arslan, Meltem Tas Kucukaydin, Ozgur Ceylan, Merzoug Benahmed, Sameh Boudiba   +8 more
wiley   +1 more source

Genome-wide identification, structural homology analysis, and evolutionary diversification of the phospholipase D gene family in the venom gland of three scorpion species

BMC Genomics, 2023
Background Venom phospholipase D (PLDs), dermonecrotic toxins like, are the major molecules in the crude venom of scorpions, which are mainly responsible for lethality and dermonecrotic lesions during scorpion envenoming.
Masoumeh Baradaran, Fatemeh Salabi
doaj   +1 more source