Results 61 to 70 of about 5,580 (197)

Scorpion venoms and associated toxins as anticancer agents: update on their application and mechanism of action

, 2020
Cancer remains one of the deadliest non-infectious diseases of the 21st century, causing millions of mortalities per year worldwide. Analyses of conventional treatments, such as radiotherapy and chemotherapy, have shown not only a lower therapeutic ...
Raymundo Rivas, Raymundo Rene Rivas‐Caceres, Alberto Barbabosa‐Pliego, Moisés Cipriano‐Salazar, Erasto Desales Salazar, Ameer Khuso, Moisés Cipriano-Salazar, Alberto Barbabosa-Pliego1, Erasto Desales‐Salazar, Ameer Khusro   +9 more
core   +1 more source

Defensive Venoms: Is Pain Sufficient for Predator Deterrence?

Toxins, 2020
Pain, though unpleasant, is adaptive in calling an animal’s attention to potential tissue damage. A long list of animals representing diverse taxa possess venom-mediated, pain-inducing bites or stings that work by co-opting the pain-sensing pathways of ...
Crystal N. Niermann, Travis G. Tate, Amber L. Suto, Rolando Barajas, Hope A. White, Olivia D. Guswiler, Stephen M. Secor, Ashlee H. Rowe, Matthew P. Rowe   +8 more
doaj   +1 more source

Integration of phylogenomics and molecular modeling reveals lineage-specific diversification of toxins in scorpions [PDF]

PeerJ, 2018
Scorpions have evolved a variety of toxins with a plethora of biological targets, but characterizing their evolution has been limited by the lack of a comprehensive phylogenetic hypothesis of scorpion relationships grounded in modern, genome-scale ...
Carlos E. Santibáñez-López, Ricardo Kriebel, Jesús A. Ballesteros, Nathaniel Rush, Zachary Witter, John Williams, Daniel A. Janies, Prashant P. Sharma   +7 more
doaj   +2 more sources

Exploring Floristic Diversity and Medicinal Plant Uses in Venda, Limpopo, South Africa

Feddes Repertorium, Volume 137, Issue 2, June 2026.
ABSTRACT Plants have been an important source of medicine for thousands of years. To better understand the current diversity and usage of medicinal plants, floristic studies are essential. This report documents an expedition conducted in the Venda region of Limpopo, South Africa. The study was carried out in Shanzha and surrounding villages, as well as
Gurusamy Manikandan, Iliassou L. Mouafon, David R. Katerere   +2 more
wiley   +1 more source

Evaluation of Storage Conditions and Pre‐Treatment Methods to Mitigate Aflatoxin Contamination in Commonly Used Chinese Herbal Medicines

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
High temperature and humidity significantly promote aflatoxin contamination in herbal medicines. This research demonstrates that drying, vacuum packaging, and sulfur fumigation are effective strategies to minimize contamination and extend shelf life, whereas UV exposure proves ineffective for decontamination.
Tung Leong Fong, Tingyuan Xing, Yau‐Tuen Chan, Zixin Feng, Guoyi Tang, Yibin Feng, Cheng Zhang, Ning Wang   +7 more
wiley   +1 more source

EP80317 Restrains Inflammation and Mortality Caused by Scorpion Envenomation in Mice

Frontiers in Pharmacology, 2019
Over 1 million cases of scorpion stings are estimated every year, whereas current treatment is limited to antivenom serum combined with supportive therapy.
Karina F. Zoccal, Karina F. Zoccal, Luiz G. Gardinassi, Karla C. F. Bordon, Eliane C. Arantes, Sylvie Marleau, Huy Ong, Lúcia H. Faccioli   +7 more
doaj   +1 more source

Genome-wide identification, structural homology analysis, and evolutionary diversification of the phospholipase D gene family in the venom gland of three scorpion species

BMC Genomics, 2023
Background Venom phospholipase D (PLDs), dermonecrotic toxins like, are the major molecules in the crude venom of scorpions, which are mainly responsible for lethality and dermonecrotic lesions during scorpion envenoming.
Masoumeh Baradaran, Fatemeh Salabi
doaj   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Primary structure of toxin IV of Leiurus quinquestriatus quinquestriatus Characterization of a new group of scorpion toxins

, 1985
We report the sequence of toxin IV of Leiurus quinquestriatus quinquestriatus, one of the five toxins lethal for the mouse purified from the venom of this scorpion.
Rochat, Hervé, Gérard Martinez, Charles Kopeyan, Kopeyan, Charles, Hervé Rochat, Martinez, Gérard   +5 more
core   +1 more source

Revitalizing endangered mycocultural heritage in Mesoamerica: The case of the Tlahuica‐Pjiekakjoo culture

PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 907-923, May 2026.
The preservation and revitalization of mycocultural heritage, developed over centuries of human‐mushroom interaction, contributes to safeguarding both natural ecosystems and the promotion of sustainable rural development, one of the biggest global challenges currently faced by humankind.
Elisette Ramírez‐Carbajal, Magdalena Martínez‐Reyes, Olivia Ayala‐Vásquez, Rodríguez‐Evangelista Fabiola, Mayra Lagunes Reyes, Faustino Hernández‐Santiago, Mónica Rangel Villafranco, Fuqiang Yu, Jesús Pérez‐Moreno   +8 more
wiley   +1 more source