Results 41 to 50 of about 5,580 (197)

Scorpions from the primeval subgenus Archaeotityus produce putative homologs of Tityus serrulatus toxins active on voltage-gated sodium channels

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
It has been proposed that the subgenus Archaeotityus comprises the most ancient species group within the medically important scorpion genus Tityus. cDNA encoding sodium-channel active toxins from the type species of this subgenus, Tityus clathratus ...
A Borges, MJ Jowers, S Bónoli, L De Sousa   +3 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

The scorpion toxin and the potassium channel

eLife, 2013
The structure of a complex containing a toxin bound to a potassium ion channel has been solved for the first time, revealing how scorpions have designed toxins that can recognize and target the filter that controls the movement of potassium ions through these channels.
openaire   +3 more sources

First Assessment of Genetic Damage in the Speckled Cockroach (Nauphoeta cinerea) After Consumption of Lettuce (Lactuca sativa) Cultivated and Commercialized in Northeastern, Brazil

Environmental Toxicology, EarlyView.
ABSTRACT This study reports, for the first time, the use of the speckled cockroach Nauphoeta cinerea as a promising bioindicator for genotoxic monitoring. It was validated through control groups (both positive and negative) in addition to testing lettuce (Lactuca sativa ) samples from public street markets consumed by N. cinerea specimens in Pernambuco,
Aleson Aparecido da Silva, Eduardo Henrique da Silva Melo, Érima Maria de Amorim, Maria Gislaine Pereira, Claudia Rohde   +4 more
wiley   +1 more source

Simultaneous modifications of sodium channel gating by two scorpion toxins

, 1982
The effects of purified scorpion toxins from two different species on the kinetics of sodium currents were evaluated in amphibian myelinated nerves under voltage clamp. A toxin from Leiurus quinquestriatus slowed and prevented sodium channel inactivation,
Strichartz, G., Wang, G.K.
core   +1 more source

Art v 1 and Amb a 4 Co‐Sensitization Identifies Italian Patients at Risk for Mugwort‐Celery‐Spice Syndrome

Allergy, EarlyView.
Three molecular profiles identified among Art v 1/Amb a 4‐sensitized patients: Art v 1 monosensitization, Amb a 4 monosensitization, and dual sensitization to both allergens. Art v 1 monosensitization was predominantly associated with allergic rhinitis, reflecting a classical airborne allergy pattern.
Enrico Scala, Gabriella Cusa, Valeria Villella, Damiano Abeni, Mauro Giani, Emma Cristina Guerra, Maria Locanto, Giorgia Meneguzzi, Lia Pirrotta, Donato Quaratino, Alessandra Zaffiro, Elisabetta Caprini, Maria Barrale, Ignazio Brusca, Valerio Pravettoni, Lorenzo Cecchi, Danilo Villalta, Martina Aumayr, Irene Mittermann, Christian Lupinek, Riccardo Asero   +20 more
wiley   +1 more source

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

Toxins, 2016
To date, several families of peptide toxins specifically interacting with ion channels in scorpion venom have been described. One of these families comprise peptide toxins (called KTxs), known to modulate potassium channels.
Caroline M. Cremonez, Mohitosh Maiti, Steve Peigneur, Juliana Silva Cassoli, Alexandre A. A. Dutra, Etienne Waelkens, Eveline Lescrinier, Piet Herdewijn, Maria Elena de Lima, Adriano M. C. Pimenta, Eliane C. Arantes, Jan Tytgat   +11 more
doaj   +1 more source

She Doesn't Whisper: Female‐Prominent Stridulation Shaped by Morphology in a Buthid Scorpion and Insights on Its Function

Ethology, EarlyView.
Sexual dimorphism and stress‐induced stridulatory responses in Jaguajir rochae (Borelli, 1910). Females exhibited greater absolute pectinal size and higher sound pressure levels, whereas males showed higher pectinal allometric ratios relative to body size, lower sound frequencies, and shorter delta times.
Welton Dionisio‐da‐Silva, Natália Maria Câmara Luna, Patrício Adriano da Rocha, Rodrigo Hirata Willemart, Marcio Bernardino daSilva   +4 more
wiley   +1 more source

Refined solution structure of the anti-mammal and anti-insect LqqIII scorpion toxin: Comparison with other scorpion toxins

, 1997
International audienceThe solution structure of the anti-mammal and anti-insect LqqIII toxin from the scorpion Leiurus quinquestriatus quinquestriatus was refined and compared with other long-chain scorpion toxins.
Rochat, Hervé, Bonmatin, J.M., Vovelle, Françoise, Ptak, Marius, Landon, Céline, Sodano, Patrick, Kopeyan, Charles, Cornet, C.   +7 more
core   +1 more source

Insects and Survival: A Review of Primary and Secondary Defense Strategies

Entomologia Experimentalis et Applicata, Volume 174, Issue 7, Page 601-624, July 2026.
Based on a review of three decades of literature, insect defense mechanisms are classified into primary (I) and secondary (II) mechanisms of behavioral, morphological, and chemical nature. These mechanisms have been recorded in 22 (I) and 20 (II) orders, respectively.
Lucas Fernandes Silva, Rodrigo Almeida Pinheiro, José Cola Zanuncio, Conceição Aparecida dos Santos   +3 more
wiley   +1 more source