Results 41 to 50 of about 9,314 (214)

Evaluation of the lethal potency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes. [PDF]

open access: yes, 2014
International audienceScorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide.
Bouhaouala, Balkiss   +6 more
core   +4 more sources

Southern African scorpion toxins: An overview

open access: yesToxicon, 2008
In southern Africa there are 130 species of scorpions and only a few species' venom have been investigated to date. This review gives an overview of the research done on the venom of southern African scorpions and the toxins and peptides identified up to date.
Du Plessis, L.H.   +2 more
openaire   +3 more sources

Scorpionism in Brazil in the years 2000 to 2012 [PDF]

open access: yes, 2014
Background: Scorpionism is a serious public health problem in Brazil. Nationwide epidemiological analyses of scorpion stings are scarce. In this context, the present study aims to provide an epidemiological analysis of accidents involving scorpions in ...
Pinto Júnior, Vitor Laerte   +1 more
core   +4 more sources

Isolation and Characterization of Insecticidal Toxins from the Venom of the North African Scorpion, Buthacus leptochelys

open access: yesToxins, 2019
Various bioactive peptides have been identified in scorpion venom, but there are many scorpion species whose venom has not been investigated. In this study, we characterized venom components of the North African scorpion, Buthacus leptochelys, by mass ...
Yusuke Yoshimoto   +5 more
doaj   +1 more source

Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components [PDF]

open access: yes, 2010
Background Lychas mucronatus is one scorpion species widely distributed in Southeast Asia and southern China. Anything is hardly known about its venom components, despite the fact that it can often cause human accidents.
Zhao Ruiming   +6 more
core   +2 more sources

Insect-selective spider toxins targeting voltage-gated sodium channels [PDF]

open access: yes, 2007
The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate Nav channel gating.
Nicholson, GM
core   +1 more source

A Combinational Strategy upon RNA Sequencing and Peptidomics Unravels a Set of Novel Toxin Peptides in Scorpion Mesobuthus martensii

open access: yesToxins, 2016
Scorpion venom is deemed to contain many toxic peptides as an important source of natural compounds. Out of the two hundred proteins identified in Mesobuthus martensii (M. martensii), only a few peptide toxins have been found so far.
Ning Luan   +8 more
doaj   +1 more source

Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the Middle East and North Africa.

open access: yesPLoS Neglected Tropical Diseases, 2021
The Middle East and Northern Africa, collectively known as the MENA region, are inhabited by a plethora of venomous animals that cause up to 420,000 bites and stings each year. To understand the resultant health burden and the key variables affecting it,
Timothy P Jenkins   +10 more
doaj   +1 more source

Functional Properties and Toxin Pharmacology of a Dorsal Root Ganglion Sodium Channel Viewed through its Voltage Sensors [PDF]

open access: yes, 2013
The voltage-activated sodium (Nav) channel Nav1.9 is expressed in dorsal root ganglion (DRG) neurons where it is believed to play an important role in nociception.
Bean, Bruce Palmer   +4 more
core   +1 more source

Characterization of a Novel BmαTX47 Toxin Modulating Sodium Channels: The Crucial Role of Expression Vectors in Toxin Pharmacological Activity

open access: yesToxins, 2014
Long-chain scorpion toxins with four disulfide bridges exhibit various pharmacological features towards the different voltage-gated sodium channel subtypes. However, the toxin production still remains a huge challenge.
Tian Li   +6 more
doaj   +1 more source

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