Results 21 to 30 of about 5,580 (197)
Toxins, 2019 Various bioactive peptides have been identified in scorpion venom, but there are many scorpion species whose venom has not been investigated. In this study, we characterized venom components of the North African scorpion, Buthacus leptochelys, by mass ...
Yusuke Yoshimoto +5 more
doaj +2 more sources
Voltage-Gated K+/Na+ Channels and Scorpion Venom Toxins in Cancer [PDF]
Frontiers in Pharmacology, 2020 Ion channels have recently been recognized as novel therapeutic targets in cancer research since they are overexpressed in different histological tissues, and their activity is linked to proliferation, tumor progression, angiogenesis, metastasis, and ...
Alexis Díaz-García +3 more
doaj +2 more sources
[Scorpion toxins and defensins].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1998 Les venins de scorpion contiennent un grand nombre de neurotoxines peptidiques qui constituent un ensemble de familles moléculaires à haut degré de polymorphisme, mais qui ont en commun une architecture semblable. Cette architecture se retrouve dans des peptides antibactériens circulants de la famille des défensines, qui s'apparentent tout ...
Goyffon, M, Landon, C.
openaire +3 more sources
Scorpion toxins for the reversal of BoNT-induced paralysis. [PDF]
Bioorg Med Chem Lett, 2013 The botulinum neurotoxins, characterized by their neuromuscular paralytic effects, are the most toxic proteins known to man. Due to their extreme potency, ease of production, and duration of activity, the BoNT proteins have been classified by the Centers for Disease Control as high threat agents for bioterrorism.
Lowery CA, Adler M, Borrell A, Janda KD.
europepmc +4 more sources
FEBS Open Bio, 2021 Buthus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of envenomation in Morocco, no study has focused yet on the proteomic composition of the Moroccan B ...
Khadija Daoudi +8 more
doaj +2 more sources
Scorpion Toxins and Ion Channels: Potential Applications in Cancer Therapy [PDF]
Toxins, 2020 CARLOS José Correia De Santana +2 more
exaly +2 more sources
The European Zoological Journal, 2022 Scorpion venom plays an important role in scorpion predation, competition, communication, and defense. In this study, the species identification of Shandong scorpion and the analysis of venom extracted from male and female scorpion at the transcriptome ...
Y. Yang +12 more
doaj +1 more source
The Oncologist, EarlyView., 2021 Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi +21 more
wiley +1 more source
Life, 2023 Morocco is known to harbor two of the world’s most dangerous scorpion species: the black Androctonus mauritanicus (Am) and the yellow Buthus occitanus (Bo), responsible for 83% and 14% of severe envenomation cases, respectively.
Ines Hilal +7 more
doaj +1 more source
Subtype Specificity of β-Toxin Tf1a from Tityus fasciolatus in Voltage Gated Sodium Channels
Toxins, 2018 Scorpion venoms are a complex mixture of components. Among them the most important are peptides, which presents the capacity to interact and modulate several ion channel subtypes, including voltage-gated sodium channels (NaV).
Daniel Oliveira da Mata +6 more
doaj +1 more source