Results 11 to 20 of about 4,656 (172)
Autonomic effects of some scorpion venoms and toxins [PDF]
Clinical and Experimental Pharmacology and Physiology, 2002 Summary1. The autonomic effects of venoms and toxins from several species of scorpions, including the Indian red scorpion Mesobuthus tamulus, the Chinese scorpion Buthus martensi Karsch and the Israeli scorpion Leiurus quinquestriatus quinquestriatus, all belonging to Buthidae, and the Asian black scorpions Heterometrus longimanus and Heterometrus ...
Selvanayagam Nirthanan +1 more
exaly +4 more sources
Analysis of the Proteome and Biochemistry of Venom from Tityus confluens, a Scorpion That Can Be Involved in Severe Envenomation Cases in Brazil [PDF]
ToxinsIn Brazil, the annual scorpion sting cases surpass those of other neglected tropical diseases, highlighting a significant public health issue. The severity of scorpion envenomation relates to the venom’s rapid action, complex composition, species ...
Laís Corrêa Lima +12 more
doaj +2 more sources
Scorpion toxins for the reversal of BoNT-induced paralysis. [PDF]
Bioorg Med Chem Lett, 2013 The botulinum neurotoxins, characterized by their neuromuscular paralytic effects, are the most toxic proteins known to man. Due to their extreme potency, ease of production, and duration of activity, the BoNT proteins have been classified by the Centers for Disease Control as high threat agents for bioterrorism.
Lowery CA, Adler M, Borrell A, Janda KD.
europepmc +4 more sources
Scorpion Toxins and Ion Channels: Potential Applications in Cancer Therapy [PDF]
Toxins, 2020 Fontes W +2 more
exaly +2 more sources
The European Zoological Journal, 2022 Scorpion venom plays an important role in scorpion predation, competition, communication, and defense. In this study, the species identification of Shandong scorpion and the analysis of venom extracted from male and female scorpion at the transcriptome ...
Y. Yang +12 more
doaj +1 more source
The Oncologist, EarlyView., 2021 Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi +21 more
wiley +1 more source
Genomic and structural characterization of Kunitz-type peptide LmKTT-1a highlights diversity and evolution of scorpion potassium channel toxins. [PDF]
PLoS ONE, 2013 BACKGROUND: Recently, a new subfamily of long-chain toxins with a Kunitz-type fold was found in scorpion venom glands. Functionally, these toxins inhibit protease activity and block potassium channels.
Zongyun Chen +10 more
doaj +1 more source
Frontiers in Pharmacology, 2021 The Indian red scorpion (Mesobuthus tamulus) is one of the world’s deadliest scorpions, with stings representing a life-threatening medical emergency. This species is distributed throughout the Indian sub-continent, including eastern Pakistan, eastern ...
Bhabana Das +3 more
doaj +1 more source
Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels. [PDF]
PLoS ONE, 2015 Scorpion toxins are important pharmacological tools for probing the physiological roles of ion channels which are involved in many physiological processes and as such have significant therapeutic potential.
Rym ElFessi-Magouri +6 more
doaj +1 more source
Scorpion Venom: Detriments and Benefits
Biomedicines, 2020 Scorpion venom may cause severe medical complications and untimely death if injected into the human body. Neurotoxins are the main components of scorpion venom that are known to be responsible for the pathological manifestations of envenoming.
Shirin Ahmadi +8 more
doaj +1 more source