Toxins, 2020 The Hemiscorpius lepturus scorpion and brown spider Loxosceles intermedia represent a public health problem in Asia and America, respectively. Although distinct, these organisms contain similar toxins responsible for the principal clinical signs of ...
Ramla Ben Yekhlef +9 more
doaj +1 more source
Structure-function strategies to improve the pharmacological value of animal toxins. [PDF]
, 2006 ISBN : 978-0-12-369442-3Animal venoms are rich sources of bioactive compounds that possess obvious pharmacological, therapeutic and/or biotechnological values.
de Waard, Michel, Sabatier, Jean-Marc
core +3 more sources
Scorpion toxins specific for Na+‐channels [PDF]
European Journal of Biochemistry, 1999 Na+‐channel specific scorpion toxins are peptides of 60–76 amino acid residues in length, tightly bound by four disulfide bridges. The complete amino acid sequence of 85 distinct peptides are presently known. For some toxins, the three‐dimensional structure has been solved by X‐ray diffraction and NMR spectroscopy.
Possani, Lourival D. +3 more
openaire +3 more sources
Exploring the Inter- and Intra-Specific Variability of Androctonus Scorpion Venoms
Biology and Life Sciences Forum, 2023 Scorpion venom possesses a lethal sting and potential medicinal properties, making it a captivating natural elixir. Our study aimed to unravel the composition of Androctonus scorpionvenoms in Morocco.
Ines Hilal +5 more
doaj +1 more source
Isolation, chemical and functional characterization of several new K+-channel blocking peptides from the venom of the scorpion Centruroides tecomanus [PDF]
, 2018 K
Balajthy, András +6 more
core +1 more source
Probing pattern and dynamics of disulfide bridges using synthesis and NMR of an ion channel blocker peptide toxin with multiple diselenide bonds [PDF]
, 2016 Anuroctoxin (AnTx), a 35-amino-acid scorpion toxin containing four disulfide bridges, is a high affinity blocker of the voltage-gated potassium channel Kv1.3, but also blocks Kv1.2.
Bartok, Adam +9 more
core +2 more sources
Venoms of Iranian Scorpions (Arachnida, Scorpiones) and Their Potential for Drug Discovery
Molecules, 2019 Scorpions, a characteristic group of arthropods, are among the earliest diverging arachnids, dating back almost 440 million years. One of the many interesting aspects of scorpions is that they have venom arsenals for capturing prey and defending against ...
Seyed Mahdi Kazemi, Jean-Marc Sabatier
doaj +1 more source
Isolation and characterization of CvIV4: a pain inducing α-scorpion toxin. [PDF]
PLoS ONE, 2011 Among scorpion species, the Buthidae produce the most deadly and painful venoms. However, little is known regarding the venom components that cause pain and their mechanism of action. Using a paw-licking assay (Mus musculus), this study compared the pain-
Ashlee H Rowe +6 more
doaj +1 more source
Primary structure and electrophysiological characterization of two almost identical isoforms of toxin from Isometrus vittatus (family: Buthidae) scorpion venom. [PDF]
, 2003 Two almost identical proteins with 70 amino acid residues each, closely packed by four disufide bridges, and molecular masses of 7899.5 and 7884.7 were isolated and sequenced from the venom of the scorpion Isometrus vittatus from Pakistan. They differ by
C.V.F. Batista +7 more
core +2 more sources
Hard‐Magnetic Soft Millirobots in Underactuated Systems
Advanced Robotics Research, EarlyView.This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang +4 more
wiley +1 more source