Results 71 to 80 of about 11,648 (223)

Scorpion Venom and Its Different Peptides Aid in Treatment Focusing on Cancer Disease with the Mechanism of Action

open access: yesTrends in Pharmacy
Animal venoms, especially those from scorpions, have garnered interest for their potential therapeutic uses. Scorpion venom is a complex mixture of bioactive compounds, including neurotoxins, enzymes, enzyme inhibitors, and peptides. These peptides have
Radwa Abdallnasser Amen   +1 more
doaj   +3 more sources

Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones)

open access: yesBMC Genomics, 2007
Background Scorpions like other venomous animals posses a highly specialized organ that produces, secretes and disposes the venom components. In these animals, the last postabdominal segment, named telson, contains a pair of venomous glands connected to ...
Rodríguez de la Vega Ricardo C   +3 more
doaj   +1 more source

Evolution of Phospholipase A2 in Bees and Flies

open access: yesEcology and Evolution, Volume 15, Issue 10, October 2025.
This study investigated the evolution of the PLA2 gene in bees and flies and compared the evolutionary rate between them, which denotes the toxic group and the non‐toxic group. The results showed that PLA2 was under purifying selection and that an accelerated evolution of PLA2 occurred in the toxic group when compared with the non‐toxic group ...
Siqi Yang, Minyu Wu, Ping Feng
wiley   +1 more source

Cardiotoxic and Arrhythmogenic Effects of Hemiscorpius lepturus Scorpion Venom in Rats [PDF]

open access: yes, 2015
Background: Envenomation by Hemiscorpius lepturus is not painful and the clinical manifestations include bloody urine due to hemoglobinuria or hematuria, dermonecrotic reactions,cardiac arrhythmia and in minority of cases acute renal failure which may ...
Evazy, Reihane   +7 more
core   +2 more sources

The scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 opening [PDF]

open access: yes, 2015
We identified Tf2, the first β-scorpion toxin from the venom of the Brazilian scorpion Tityus fasciolatus. Tf2 is identical to Tb2-II found in Tityus bahiensis.We found that Tf2 selectively activates human (h)Nav1.3, a neuronal voltage-gated sodium (Nav)
Bosmans, Frank   +4 more
core   +3 more sources

Short Peptides from Asian Scorpions: Bioactive Molecules with Promising Therapeutic Potential

open access: yesToxins
Scorpion venom peptides, particularly those derived from Asian species, have garnered significant attention, offering therapeutic potential in pain management, cancer, anticoagulation, and infectious diseases.
Kaiyun Xin   +9 more
doaj   +1 more source

Scorpion Venom Causes Apoptosis by Increasing Reactive Oxygen Species and Cell Cycle Arrest in MDA-MB-231 and HCT-8 Cancer Cell Lines

open access: yesJournal of Evidence-Based Integrative Medicine, 2018
Objectives. The objective of this study was to examine the effect of scorpion venoms on cancer cell progression, apoptosis, and cell cycle arrest. Scorpion venoms are known to possess numerous bioactive compounds that act against cancer progression by ...
Abdulrahman Khazim Al-Asmari PhD   +2 more
doaj   +1 more source

Partial purification of peptides present in the Tityus macrochirus (Buthidae) scorpion venom and preliminary assessment of their cytotoxicity

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introduction: Scorpion venom contains peptides with neurotoxic action primarily active on ion channels in the nervous system of insects and mammals. They are also characterized as cytolytic and anticancer, biological characteristics that have not yet ...
Clara Andrea Rincón-Cortés   +2 more
doaj   +1 more source

Education in Family Medicine : What has been achieved? [PDF]

open access: yes, 2012
Contents: Education... historical landmarks - Pierre Mallia; The Malta College of Family Doctors and the Royal College of General Practitioners - John V.
Agius, Dominic   +2 more
core  

Neurotransmitter evaluation in the hippocampus of rats after intracerebral injection of TsTX scorpion toxin [PDF]

open access: yes, 2009
TsTX is an a-type sodium channel toxin that stimulates the discharge of neurotransmitters from neurons. In the present study we investigated which neurotransmitters are released in the hippocampus after TsTX injection and if they are responsible for ...
BARRETO, S. A   +5 more
core   +2 more sources

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