Results 111 to 120 of about 5,167 (220)

The scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 opening [PDF]

, 2015
We identified Tf2, the first β-scorpion toxin from the venom of the Brazilian scorpion Tityus fasciolatus. Tf2 is identical to Tb2-II found in Tityus bahiensis.We found that Tf2 selectively activates human (h)Nav1.3, a neuronal voltage-gated sodium (Nav)
Bosmans, Frank, Camargos, Thalita Soares, Mourão, Caroline Barbosa Farias, Rego, Solange Cristina, Schwartz, Elisabeth Nogueira Ferroni   +4 more
core   +3 more sources

First transcriptome analysis of the venom glands of the scorpion Hottentotta zagrosensis (Scorpions: Buthidae) with focus on venom lipolysis activating peptides

Frontiers in Pharmacology
IntroductionScorpion venom is a rich source of biological active peptides and proteins. Transcriptome analysis of the venom gland provides detailed insights about peptide and protein venom components. Following the transcriptome analysis of different species in our previous studies, our research team has focused on the Hottentotta zagrosensis as one of
Fatemeh Salabi, Hedieh Jafari, Masoud Mahdavinia, Reza Azadnasab, Saeedeh Shariati, Saeedeh Shariati, Mahsa Lari Baghal, Majid Tebianian, Masoumeh Baradaran   +8 more
openaire   +3 more sources

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes [PDF]

, 2017
Venom systems have evolved on multiple occasions across the animal kingdom, and they can act as key adaptations to protect animals from predators. Consequently, venomous animals serve as models for a rich source of mimicry types, as non-venomous ...
Amanda Nouwens, Anthony Romilio, Bryan G. Fry, Gavan M. Cooke, Gregory C. Bird, Han Han, Irina Vetter, Ivan Koludarov, Ivo Que, James Dobson, Jeroen C. Visser, Jordan Debono, Karen L. Cheney, Karine Mardon, Kate Baumann, Louise van der Weerd, Michael K. Richardson, Michael Morgan, Nicholas R. Casewell, Sanjaya Kuruppu, Simon C. Wagstaff, Syed A. Ali, Vera Weisbecker, Wayne C. Hodgson   +23 more
core   +6 more sources

Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. [PDF]

, 2020
Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
Barreto, Natália, Bonfanti, Amanda Pires, Brunetto, Sérgio, Caballero, Marcus, Cordeiro, Gabriel, Moura, Fernanda, Munhoz, Jaqueline, Ramos, Celso Dario, Rapôso, Catarina, Rocha-E-Silva, Thomaz, Sutti, Rafael, Thome, Rodolfo, Verinaud, Liana   +12 more
core   +1 more source

Functional Properties and Toxin Pharmacology of a Dorsal Root Ganglion Sodium Channel Viewed through its Voltage Sensors [PDF]

, 2013
The voltage-activated sodium (Nav) channel Nav1.9 is expressed in dorsal root ganglion (DRG) neurons where it is believed to play an important role in nociception.
Bean, Bruce Palmer, Bosmans, Frank, Martin-Eauclaire, Marie-France, Puopolo, Michelino, Swartz, Kenton J.   +4 more
core   +1 more source

Sequencing and comparative-bioinformatic analysis of chlorotoxin-like peptide from Iranian scorpion Mesobuthus eupeus [PDF]

, 2011
زمینه و هدف: در سال های اخیر نوروتوکسین های عقرب از لحاظ خواص دارویی و اثرات فیزیولوژیک مورد مطالعات زیادی قرار گرفته اند. یکی از این توکسین ها که توجه زیادی را به خود جلب کرده است، کلروتوکسین می باشد که هم اکنون در درمان سرطان های مغز مورد استفاده قرار ...
Ahadi, AliMohammad., Ayat, Hoda., Ilkhanizade, sheida., pirali kheirabadi, Khodadad.   +3 more
core   +1 more source

Mesobuthus Venom-Derived Antimicrobial Peptides Possess Intrinsic Multifunctionality and Differential Potential as Drugs

Frontiers in Microbiology, 2018
Animal venoms are a mixture of peptides and proteins that serve two basic biological functions: predation and defense against both predators and microbes. Antimicrobial peptides (AMPs) are a common component extensively present in various scorpion venoms
Bin Gao, Shunyi Zhu
doaj   +1 more source

Pleiotropic Anticancer Properties of Scorpion Venom Peptides: Rhopalurus princeps Venom as an Anticancer Agent. [PDF]

Drug Des Devel Ther, 2020
Mikaelian AG, Traboulay E, Zhang XM, Yeritsyan E, Pedersen PL, Ko YH, Matalka KZ.   +6 more
europepmc   +1 more source

Ioncsatornák szerepe az immunrendszer sejtjeinek differenciálódásában és proliferációjában = The role of ion channels in differentiation and proliferation of immune cells. [PDF]

, 2007
Elektrofiziológiai és biokémiai módszerek kombinálásával számos új, potenciálisan immunszuppresszív hatású Kv1.3 ioncsatorna blokkoló toxint fedeztünk fel, melyeket a az Anurotonus phaiodactylus, a Centruroides elegans Thorell, a Centruroides suffusus ...
Bagdány, Miklós, Gáspár, Rezső, Hajdú, Péter, Panyi, György, Varga, Zoltán   +4 more
core  

Avancées et nouvelles technologies en Toxinologie

, 2010
Collection Rencontres en Toxinologie ISSN 1760-6004 ; http://sfet.asso.fr/images/stories/SFET/pdf/Ebook-RT18-2010-signets-110322.pdfInternational ...
Barbier, Julien, Benoit, Evelyne, Marchot, P., Mattei, César, Servent, Denis   +4 more
core