Results 121 to 130 of about 5,167 (220)

Expression of defensins in non-infected araneomorph spiders [PDF]

, 2018
Defensins are a major family of antimicrobial peptides found throughout the phylogenetic tree. From the spider species: Cupiennius salei, Phoneutria reidyi, Polybetes pythagoricus, Tegenaria atrica, and Meta menardi, defensins belonging to the ‘ancestral'
Baumann, Tommy, Kuhn-Nentwig, Lucia, Largiadèr, Carlo, Nentwig, Wolfgang   +3 more
core  

Unraveling neuroprotection with Kv1.3 potassium channel blockade by a scorpion venom peptide

Scientific Reports
AbstractVoltage-gated potassium channels play a crucial role in cellular repolarization and are potential therapeutic targets in neuroinflammatory disorders and neurodegenerative diseases. This study explores Tityus bahiensis scorpion venom for neuroactive peptides. We identified the αKtx12 peptide as a potent neuroprotective agent.
Emidio Beraldo-Neto, Vanessa Florentino Ferreira, Hugo Vigerelli, Karolina Rosa Fernandes, Maria Aparecida Juliano, Ana Leonor Abrahao Nencioni, Daniel Carvalho Pimenta   +6 more
openaire   +3 more sources

The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinity [PDF]

, 2005
Acid-sensing ion channels (ASICs) are ion channels activated by extracellular protons. They are involved in higher brain functions and perception of pain, taste, and mechanical stimuli.
Chen, Xuanmao
core   +1 more source

toxines et signalisation

, 2009
Collection Rencontres en toxinologie ISSN: 1760-6004 ; http://sfet.asso.fr/images/stories/SFET/pdf/EBook-RT17-2009-signets.pdfInternational ...
Benoit, Evelyne, Goudey-Perriere, Françoise, Marchot, P., Servent, Denis   +3 more
core  

Tityus serrulatus Scorpion Venom-Induced Nociceptive Responses Depend on TRPV1, Immune Cells, and Pro-Inflammatory Cytokines

Toxins
For centuries, researchers have been fascinated by the composition of scorpion venom and its local and systemic effects on humans. During a sting, scorpions inject peptides and proteins that can affect immune cells and neurons.
Camila R. Ferraz, Marília F. Manchope, Mariana M. Bertozzi, Telma Saraiva-Santos, Ketlem C. Andrade, Anelise Franciosi, Tiago H. Zaninelli, Julia Bagatim-Souza, Sergio M. Borghi, Denise M. Cândido, Thiago M. Cunha, Rubia Casagrande, Fábio H. Kwasniewski, Waldiceu A. Verri   +13 more
doaj   +1 more source

جداسازی و خالص‌سازی فراکسيون‌های سمی زهر عقرب مزوبوتوس اپيوس [PDF]

, 2006
زمينه: عقرب مزوبوتوس اپيوس (Mesobuthus eupeus) از عقرب‌های خانواده بوتيده (Buthidae) بومی ايران به ويژه در منطقه خوزستان می‌باشد. زهر عقرب‎ها به ويژه عقرب‎های خانواده بوتيده از ترکيبات فعال بيولوژيکی مختلف از جمله انواع توکسين‌ها تشکيل شده است.
آموزگاری, زهره, حنیفی, حسین, کدخدایی, منیژه   +2 more
core  

Mass spectrometric analysis of Odonthobuthus Doriae scorpion venom and its non-neutralized fractions after interaction with commercial antivenom

Scientific Reports
It is believed that antivenoms play a crucial role in neutralizing venoms. However, uncontrolled clinical effects appear in patients stung by scorpions after the injection of antivenom.
Adel Abdollahnia, Kiumars Bahmani, Atousa Aliahmadi, Mohammad Ali As’habi, Alireza Ghassempour   +4 more
doaj   +1 more source

Discovery of Two Novel Scorpion Venom Peptides Activating TRPML2 to Impair ZIKV Internalization. [PDF]

Toxins (Basel)
Xia Z, Yang X, He D, Chang J, Xie L, Liu Q, Jin J, Li B, Tashima AK, Kwok HF, Cao Z.   +10 more
europepmc   +1 more source

The inhibitory potential of three scorpion venom peptides against multidrug-resistant <i>Klebsiella pnemoniae</i>. [PDF]

Front Microbiol
Giugliano R, Della Marca R, Chianese A, Monti A, Donadio F, Esposito E, Doti N, Zannella C, Galdiero M, De Filippis A.   +9 more
europepmc   +1 more source

Peptidomics and pharmacological profiling of Odontobuthus doriae (Buthidae) scorpion venom at the kappa opioid receptor. [PDF]

Sci Rep
Abdollahnia A, Bata BB, Fraunhofer A, Hermes J, Atashi J, Ghassempour A, Gruber CW.   +6 more
europepmc   +1 more source