Results 1 to 10 of about 16,145 (220)

BSE can propagate in sheep co-infected or pre-infected with scrapie

open access: yesScientific Reports, 2021
To understand the possible role of mixed-prion infections in disease presentation, the current study reports the co-infection of sheep with bovine spongiform encephalopathy (BSE) and scrapie.
Angela Chong   +10 more
doaj   +1 more source

Evolutionary biology and the risk of scrapie disease in sheep [PDF]

open access: yesOpen Veterinary Journal, 2018
Scrapie in sheep occurs in two forms. Classical scrapie, along with chronic wasting disease in deer, differs from all other prion diseases in being contagious and occurring as propagating epidemics.
David Bruce Adams
doaj   +1 more source

Diagnosis in Scrapie: Conventional Methods and New Biomarkers

open access: yesPathogens, 2023
Scrapie, a naturally occurring prion disease affecting goats and sheep, comprises classical and atypical forms, with classical scrapie being the archetype of transmissible spongiform encephalopathies.
Diego Sola   +12 more
doaj   +1 more source

Prion Evolvability and the Hazard of Atypical Scrapie in Small Ruminants

open access: yesOpen Veterinary Science, 2020
Observations on strain behaviour and direct demonstrations of natural selection establish that the scrapie agent and prions in general are able to evolve.
Adams David B.
doaj   +1 more source

Iron and iron/manganese ratio in forage from Icelandic sheep farms: relation to scrapie

open access: yesActa Veterinaria Scandinavica, 2006
This study was undertaken in order to examine whether any connection existed between the amounts of iron in forage and the sporadic occurrence of scrapie observed in certain parts of Iceland.
Jóhannesson T   +4 more
doaj   +1 more source

A descriptive study of the prevalence of atypical and classical scrapie in sheep in 20 European countries

open access: yesBMC Veterinary Research, 2008
Background The development of active surveillance programmes for transmissible spongiform encephalopathies of small ruminants across Europe has led to the recent identification of a previously undetected form of ovine prion disease, 'atypical' scrapie ...
Calavas Didier   +5 more
doaj   +1 more source

PrPres in placental tissue following experimental transmission of atypical scrapie in ARR/ARR sheep is not infectious by Tg338 mouse bioassay.

open access: yesPLoS ONE, 2022
Nor98-like atypical scrapie is a sporadic disease that affects the central nervous system of sheep and goats that, in contrast to classical scrapie, is not generally regarded as naturally transmissible.
Robert B Piel   +7 more
doaj   +2 more sources

Classical scrapie in small ruminants is caused by at least four different prion strains

open access: yesVeterinary Research, 2021
The diversity of goat scrapie strains in Europe has recently been studied using bioassays in a wide collection of rodent models, resulting in the classification of classical scrapie into four different categories.
Alba Marín-Moreno   +10 more
doaj   +1 more source

Glutathione peroxidase (GPX) activity in blood of ewes on farms in different scrapie categories in Iceland

open access: yesActa Veterinaria Scandinavica, 2008
Background Preliminary studies indicated decreased glutathione peroxidase (GPX) activity in blood of ewes on scrapie-afflicted farms. Other studies have shown decreased GPX activity in brain of prion-infected mice and in prion-infected cells in vitro ...
Eiríksson Tryggvi   +4 more
doaj   +1 more source

The prevalence of atypical scrapie in sheep from positive flocks is not higher than in the general sheep population in 11 European countries

open access: yesBMC Veterinary Research, 2010
Background During the last decade, active surveillance for transmissible spongiform encephalopathies in small ruminants has been intensive in Europe. In many countries this has led to the detection of cases of atypical scrapie which, unlike classical ...
Liam Barry   +11 more
doaj   +1 more source

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