Astragalus polysaccharides augment BMSC homing via SDF-1/CXCR4 modulation: a novel approach to counteract peritoneal mesenchymal transformation and fibrosis. [PDF]
Wang F +10 more
europepmc +1 more source
Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan +4 more
wiley +1 more source
From Skin to Nerve: Mapping Tissue‐Specific Innovations in Gelatin–Dopamine Hydrogel Platforms
Gelatin and dopamine as interacting building blocks for functional tissue applications. ABSTRACT The biomimetic adhesive qualities, biocompatibility, and multifunctionality of biomaterials containing gelatin and dopamine have propelled them to the forefront of regenerative medicine.
Andreea I. Dinu +3 more
wiley +1 more source
Human mesenchymal stroma/stem-like cell-derived taxol-loaded EVs/exosomes transfer anti-tumor microRNA signatures and express enhanced SDF-1-mediated tumor tropism. [PDF]
Hass R, von der Ohe J, Luo T.
europepmc +1 more source
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao +8 more
wiley +1 more source
Needle-scalpel therapy inhibits the apoptosis of nucleus pulposus cells via the SDF-1/CXCR4 axis in a rat degenerative cervical intervertebral disc model. [PDF]
Yang W +6 more
europepmc +1 more source
Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen +5 more
wiley +1 more source
In this study, we identified a previously unrecognized function of HSD17B7 as an ERα‐binding protein that serves as a coactivator to influence trabecular bone mass in estrogen deficiency. Specifically, deleting HSD17B7 in myeloid cells enhanced the number of osteoclasts and decreased trabecular bone mass post‐OVX, compared with control OVX, mirroring ...
Junyue Zhang +7 more
wiley +1 more source
Portulaca eggliana (Portulacaceae), a new species from the Brazilian Amazonian savannas
A new species of Portulacaceae from the Amazonian savannas of northern Brazil is herein described and illustrated. Portulaca eggliana is morphologically related to P. umbraticola, but differs in the number of involucral leaves, sepal morphology, bracteole shape, and seed surface.
José Roberto Ferraz +4 more
wiley +1 more source

