By identifying unique/enriched microbial species across taxa and diet types in 318 animal species with our SSD (specificity and specificity diversity) framework, we demonstrated that host phylogeny and diet are joint drivers of microbial specificity compositional heterogeneity, potentially linking the macroecological pattern of phylosymbiosis with the ...
Zhanshan (Sam) Ma
wiley +1 more source
Portulaca oleracea L seed extracts counteract diabetic nephropathy through SDF-1/IL10/PPARγ-mediated tuning of keap1/Nrf2 and NF-κB transcription in Sprague Dawley rats. [PDF]
Aziz WM +5 more
europepmc +1 more source
Human mesenchymal stromal cells (MSCs) were engineered to secrete an isoleucine‐zippered soluble trimeric TRAIL (SCZT) and evaluated with trichostatin A (TSA) to overcome TRAIL resistance. TSA upregulated DR5 and amplified caspase‐8–dependent apoptosis in vitro; in vivo, tumor‐homing MSCs combined with TSA suppressed the growth of both TRAIL‐sensitive ...
Ryosuke Uchibori +2 more
wiley +1 more source
Expression of Concern: Long Non-Coding RNA-H19 Stimulates Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells via the MicroRNA-149/SDF-1 Axis. [PDF]
europepmc +1 more source
ABSTRACT Objective Access to appropriate oral healthcare is vital for overall health and well‐being. However, people who use drugs (PWUD) often face significant barriers in accessing oral healthcare services. This qualitative study focused on exploring the perspectives of public oral health service providers and harm reduction workers to understand the
Tejashree Kangutkar +3 more
wiley +1 more source
Overexpression of Nrf2 in bone marrow mesenchymal stem cells promotes B-cell acute lymphoblastic leukemia cells invasion and extramedullary organ infiltration through stimulation of the SDF-1/CXCR4 axis. [PDF]
Zheng L +11 more
europepmc +1 more source
Abstract Aims To explore the association between using automated insulin delivery (AID) systems and physical activity (PA) levels among people with type 1 diabetes. Methods Cross‐sectional study including 1156 participants from the BETTER Type 1 Diabetes registry.
Tamanna Chahal +10 more
wiley +1 more source
Novel Clinical Insights From a Swedish RFC1 Spectrum Disorder Cohort
In this study, we clinically characterized a Swedish cohort with biallelic RFC1 expansions by retrospectively enrolling 30 patients from a tertiary center and analyzing their clinical, genetic, and detailed phenotypic features. Our results suggest a Swedish founder effect in the Norrbotten region and indicate that RFC1‐spectrum disorder should be ...
Victor Alm +12 more
wiley +1 more source
Transcriptomics and Proteomics Reveal That TLPW Acupuncture Ameliorates Proteinuria in Diabetic Kidney Disease Model Rats by Suppressing Epithelial-to-Mesenchymal Transition via the DPP4/SDF-1<i>α</i>/TGF-<i>β</i>/Smad Signalling Axis. [PDF]
Ji Y +7 more
europepmc +1 more source

