Results 241 to 250 of about 63,696 (276)

Cytotoxicity of ammonia‐ and water‐based silver fluoride treatments

European Journal of Oral Sciences, Volume 134, Issue 1, February 2026.
Abstract This study aims to investigate the trans‐dentinal and direct cell viability of ammonia‐ and water‐based silver fluoride treatments. Deep dentin discs were prepared, balanced for permeability and autoclaved. Three‐dimensional cultures of odontoblast‐like cells were transferred to the pulpal aspect of the dentin slices inside perfusion split ...
Merve Uctasli, Roda Seseogullari‐Dirihan, Mustafa Murat Mutluay, Arzu Tezvergil‐Mutluay   +3 more
wiley   +1 more source

Immunomodulatory Mechanism of Baiyaojian Decoction on Periodontitis: Network Pharmacology, Single‐Cell RNA Sequencing and Molecular Docking

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Periodontitis is one of the most common oral inflammatory diseases. Baiyaojian decoction, known for its prominent immunomodulatory and anti‐inflammatory properties, shows significant potential in treating periodontitis, though its molecular mechanisms remain unknown. The active ingredients and therapeutic targets were determined by integrating
Bing‐jun Chen, Ming‐ming Li, Zhao‐yu Zheng, Wen‐qin Jin, Zhao Jin, Yu‐ling Zuo   +5 more
wiley   +1 more source

Unveiling the Therapeutic Potential of “Taikong Blue” Lavender Essential Oil and Its Key Compounds in Skin Problems via Network Pharmacology and In Vitro Validation

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Taikong Blue Lavender Essential Oil (TLEO) is derived from a proprietary space‐bred cultivar of Lavandula angustifolia and cultivated under pristine conditions in Xinjiang, China. TLEO has long been used by regional people to treat various skin disorders such as hyperpigmentation, trans‐epidermal water loss, collagen degradation ...
Fei Liu, Yingyu Zhang, Minhazul Abedin, Jingyi Song, Suzhen Yang, Hongxiang Lou, Xixi Dou, Junsong Xiao, Hua Wu   +8 more
wiley   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Solvation Entropy as a Lever for Steering the Macroscopic Properties of a Functional Supramolecular Helical Polymer

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The structural transition between the two fully‐characterized states of a supramolecular helical hydrogen‐bonded polymer (represented as blue and light pink stacks) can be predictably varied over 85 K by changing the nature and amount of cosolvent; entropy of solvation (schematized as solvents of different sizes) is the main lever to tune the ...
Huanjun Kong, Mayte A. Martínez‐Aguirre, Yan Li, Tomoyuki Ikai, Eiji Yashima, Gangamallaiah Velpula, Steven De Feyter, Pierre‐Antoine Albouy, Komivi Akpo, Patrick Brocorens, Roberto Lazzaroni, Laurent Bouteiller, Matthieu Raynal   +12 more
wiley   +1 more source

661. In Situ Inhibition of SDF-1/CXCR4 Axis Mediated by Knockdown of SDF-1 Prevents Pulmonary Metastasis

Molecular Therapy, 2008
openaire   +1 more source

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SDF-1 keeps HSC quiescent at home

Blood, 2011
In this issue of Blood , Tzeng et al report on the generation of adult, conditional SDF-1–deficient mice in which HSC quiescence and endosteal niche localization are impaired.[1][1] The chemokine stromal cell–derived factor 1 (SDF-1; CXCL12), and its major receptor CXCR4, regulate many ...
Tomer, Itkin, Tsvee, Lapidot
openaire   +2 more sources

Functional Characterization of SDF-1 Proximal Promoter

Journal of Molecular Biology, 2005
Stromal-cell derived factor 1 (SDF1) is a CXC chemokine that binds and signals through the CXCR4 receptor, playing an essential role in embryonic B lymphopoiesis, myelopoiesis and organogenesis. The CXCR4/SDF1 pathway is associated with several pathologies.
Carelia, García-Moruja, Juan M, Alonso-Lobo, Patricia, Rueda, Carmen, Torres, Nuria, González, Mercedes, Bermejo, Francisco, Luque, Fernando, Arenzana-Seisdedos, José, Alcamí, Antonio, Caruz   +9 more
openaire   +2 more sources

Mesenchymal stromal cells may enhance metastasis of neuroblastoma via SDF-1/CXCR4 and SDF-1/CXCR7 signaling

Cancer Letters, 2011
Bone marrow metastasis is frequently observed in patients with high-risk neuroblastoma. Mesenchymal stromal cells (MSCs) in bone marrow may enhance tumor metastasis through secreting stromal cell-derived factor-1 (SDF-1). Here we investigated neuroblastoma cell behaviors under the influence of MSCs and explored the function of SDF-1 signaling during ...
Deng, R, Chan, GCF, Ma, M, Ye, JY, Dee, CM   +4 more
openaire   +4 more sources