Evaluating the effectiveness and cost‐effectiveness of integrating mass drug administration for helminth control with seasonal malaria chemoprevention in Ghanaian children: Protocol for a cluster randomised controlled trial [PDF]
Tropical Medicine &International Health, Volume 30, Issue 1, Page 22-30, January 2025.Abstract Objectives To evaluate the effectiveness and cost‐effectiveness of integrating seasonal malaria chemoprevention (SMC) with mass drug administration for helminth control among school‐aged children living in communities where the burden of malaria and helminths is high in Ghana, West Africa.
Muhammed O. Afolabi +6 more
wiley +3 more sources
Predictors of caregiver adherence to administration of amodiaquine during delivery of seasonal malaria chemoprevention in Nigeria, Burkina Faso, Chad, and Togo [PDF]
Malaria Journal, 2023 Background Malaria is the leading cause of morbidity and mortality among infants and children under-five in sub-Saharan Africa. In the Sahel, seasonal malaria chemoprevention (SMC) is delivered door-to-door in monthly cycles.
Taiwo Ibinaiye +6 more
doaj +3 more sources
Seasonal malaria vaccination: protocol of a phase 3 trial of seasonal vaccination with the RTS,S/AS01E vaccine, seasonal malaria chemoprevention and the combination of vaccination and chemoprevention [PDF]
BMJ Open, 2020 Introduction Seasonal malaria chemoprevention (SMC), with sulphadoxine–pyrimethamine plus amodiaquine (SP+AQ) is effective but does not provide complete protection against clinical malaria.
Ismaila Thera +18 more
doaj +5 more sources
Prevalence of malaria in an area receiving seasonal malaria chemoprevention in Niger [PDF]
Malaria Journal, 2021 Background Malaria transmission is highly seasonal in Niger. Despite the introduction of seasonal malaria chemoprevention (SMC) in the Magaria District, malaria incidence remains high, and the epidemiology of malaria in the community is not well ...
Matthew E. Coldiron +11 more
doaj +2 more sources
Seasonal malaria chemoprevention: successes and missed opportunities [PDF]
Malaria Journal, 2017 Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season. Children are given a single dose of sulfadoxine/pyrimethamine combined with a 3-day course of amodiaquine, once a ...
Matthew E. Coldiron +2 more
doaj +2 more sources
Evidence that seasonal malaria chemoprevention with SPAQ influences blood and pre-erythrocytic stage antibody responses of Plasmodium falciparum infections in Niger [PDF]
Malaria Journal, 2021 Background In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity
Lamine Mahaman Moustapha +7 more
doaj +2 more sources
Seasonal vaccination against malaria: a potential use for an imperfect malaria vaccine [PDF]
Malaria Journal, 2017 In many parts of the African Sahel and sub-Sahel, where malaria remains a major cause of mortality and morbidity, transmission of the infection is highly seasonal.
Brian Greenwood +10 more
doaj +3 more sources
Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention. [PDF]
, 2021 BACKGROUND: Malaria control remains a challenge in many parts of the Sahel and sub-Sahel regions of Africa. METHODS: We conducted an individually randomized, controlled trial to assess whether seasonal vaccination with RTS,S/AS01E was noninferior to ...
Cairns, Matthew +29 more
core +4 more sources
Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children [PDF]
Nature Communications, 2019 Seasonal malaria chemoprevention provides substantial benefit for young children, but resistance to used drugs will likely develop. Here, Chotsiri et al.
Palang Chotsiri +12 more
doaj +4 more sources
Estimating the potential public health impact of seasonal malaria chemoprevention in African children [PDF]
, 2012 Seasonal malaria chemoprevention, previously known as intermittent preventive treatment in children, is highly effective in areas with a short malaria transmission season.
Cairns, M. +7 more
core +7 more sources