Prevalence of malaria in an area receiving seasonal malaria chemoprevention in Niger [PDF]
Malaria Journal, 2021 Background Malaria transmission is highly seasonal in Niger. Despite the introduction of seasonal malaria chemoprevention (SMC) in the Magaria District, malaria incidence remains high, and the epidemiology of malaria in the community is not well ...
Matthew E. Coldiron +11 more
doaj +4 more sources
Status and prospects of seasonal malaria chemoprevention among children in Sahelian countries: A systematic review and meta-analysis. [PDF]
PLOS Global Public HealthIn areas with seasonal malaria transmission, seasonal malaria chemoprevention (SMC) involves giving children a three-day course of sulfadoxine-pyrimethamine and amodiaquine once a month during the transmission season.
Medard Djedanem +4 more
doaj +3 more sources
Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children [PDF]
Nature Communications, 2019 Seasonal malaria chemoprevention provides substantial benefit for young children, but resistance to used drugs will likely develop. Here, Chotsiri et al.
Palang Chotsiri +12 more
doaj +6 more sources
Combining seasonal malaria chemoprevention with novel therapeutics for malaria prevention: a mathematical modelling study. [PDF]
PLoS Comput BiolAbstract Vaccines, monoclonal antibodies, and long-acting injectables are being developed to prevent Plasmodium falciparum malaria. These therapeutics may target multiple stages of the parasite life cycle; evidence is needed to articulate their benefits with chemoprevention and prioritise candidates for clinical development.
Braunack-Mayer L +5 more
europepmc +4 more sources
Seasonal malaria chemoprevention in northern Mozambique: a cost-effectiveness analysis [PDF]
Malaria JournalBackground Malaria is endemic in Mozambique and one of the leading causes of death in children under 5 years old. In 2020 the country adopted the WHO-recommended seasonal malaria chemoprevention (SMC) strategy and delivered the intervention in all 23 ...
Neide Canana +9 more
doaj +4 more sources
Effect of seasonal malaria chemoprevention on incidence of malaria among children under five years in Kotido and Moroto Districts, Uganda, 2021: time series analysis [PDF]
Malaria JournalBackground Seasonal malaria chemoprevention (SMC) refers to monthly administration of full treatment courses of anti-malarial medicine to children
Andrew Kwiringira +8 more
doaj +4 more sources
Pharmacokinetic considerations in seasonal malaria chemoprevention
Trends in Parasitology, 2022 Los niños africanos menores de 5 años soportan la principal carga de la mortalidad mundial por malaria. La quimioprevención estacional de la malaria (SMC) con sulfadoxina-pirimetamina (SP) más amodiaquina (AQ) administrada mensualmente durante la temporada de lluvias es una intervención altamente efectiva contra la malaria para niños de entre 3 meses y
Palang Chotsiri +2 more
openalex +3 more sources
Seasonal vaccination against malaria: a potential use for an imperfect malaria vaccine [PDF]
Malaria Journal, 2017 In many parts of the African Sahel and sub-Sahel, where malaria remains a major cause of mortality and morbidity, transmission of the infection is highly seasonal.
Brian Greenwood +10 more
doaj +3 more sources
Seasonal malaria chemoprevention: successes and missed opportunities [PDF]
Malaria Journal, 2017 Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season. Children are given a single dose of sulfadoxine/pyrimethamine combined with a 3-day course of amodiaquine, once a ...
Matthew E. Coldiron +2 more
doaj +3 more sources
Household-level effects of seasonal malaria chemoprevention in the Gambia. [PDF]
Commun Med (Lond), 2023 Abstract Background In 2022 the WHO recommended the discretionary expansion of the eligible age range for seasonal malaria chemoprevention (SMC) to children older than 4 years. Older children are at lower risk of clinical disease and severe malaria so there has been uncertainty about the cost ...
Soremekun S +11 more
europepmc +7 more sources