Results 41 to 50 of about 3,965 (238)

A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research, 2023
Background The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) for children aged 3 to 59 months, living in areas where malaria transmission is highly seasonal ...
Craig Bonnington, Sol Richardson, Godfrey Magumba, Christian Rassi, Jane Nabakooza, Denis Rubahika, Anthony Nuwa, James Tibenderana, Jimmy Opigo, Jane Achan, Richard Kajubi, Kevin Baker, Jennifer Ainsworth   +12 more
doaj   +1 more source

Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali

Frontiers in Neurology, 2022
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly, Abdoulaye K. Kone, Bourama Kane, Bouréima Guindo, Bourama Tangara, Mody Sissoko, Fayçal Maiga, Karim Traore, Aichatou Diawara, Amidou Traore, Ali Thera, Mahamadou S. Sissoko, Ogobara K. Doumbo, Mark A. Travassos, Mahamadou A. Thera   +14 more
doaj   +1 more source

Indirect benefits of seasonal malaria chemoprevention for non-malarial pediatric infections and routine antibiotic use in real-world programmatic settings: a pre-post study using positive and negative controls. [PDF]

BMC Infect Dis
Gebreegziabher EA, Ouattara M, Bountogo M, Coulibaly B, Boudo V, Ouedraogo T, Lebas E, Hu H, O'Brien KS, Hsiang MS, Glidden DV, Arnold BF, Lietman TM, Sié A, Oldenburg CE.   +14 more
europepmc   +2 more sources

Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention [PDF]

New England Journal of Medicine, 2019
Mass administration of azithromycin for trachoma control led to a sustained reduction in all-cause mortality among Ethiopian children. Whether the addition of azithromycin to the monthly sulfadoxine-pyrimethamine plus amodiaquine used for seasonal malaria chemoprevention could reduce mortality and morbidity among African children was unclear.We ...
Chandramohan, Daniel, Dicko, Alassane, Zongo, Issaka, Sagara, Issaka, Cairns, Matthew, Kuepfer, Irene, Diarra, Modibo, Barry, Amadou, Tapily, Amadou, Nikiema, Frederic, Yerbanga, Serge, Coumare, Samba, Thera, Ismaila, Traore, Abdourhamane, Milligan, Paul, Tinto, Halidou, Doumbo, Ogobara, Ouedraogo, Jean-Bosco, Greenwood, Brian   +18 more
openaire   +2 more sources

Combining malaria vaccination with chemoprevention: a promising new approach to malaria control

Malaria Journal, 2021
Malaria control has stalled in a number of African countries and novel approaches to malaria control are needed for these areas. The encouraging results of a recent trial conducted in young children in Burkina Faso and Mali in which a combination of the ...
Brian Greenwood, Matthew Cairns, Mike Chaponda, R. Matthew Chico, Alassane Dicko, Jean-Bosco Ouedraogo, Kamija S. Phiri, Feiko O. ter Kuile, Daniel Chandramohan   +8 more
doaj   +1 more source

Effectiveness of Seasonal Malaria Chemoprevention in children under 10 years of age in Senegal: a stepped-wedge cluster-randomized trial [PDF]

, 2016
This study was done to determine the effectiveness of Seasonal Malaria Chemoprevention in Senegalese children up to 10 years of age using a stepped-wedge design.
Milligan, Paul
core   +2 more sources

Impact of seasonal malaria chemoprevention based on the number of medicines doses received on malaria burden among children aged 3–59 months in Nigeria: A propensity score‐matched analysis [PDF]

Tropical Medicine &International Health, Volume 29, Issue 8, Page 668-679, August 2024.
Abstract Background Seasonal malaria chemoprevention using sulfadoxine‐pyrimethamine plus amodiaquine (sulfadoxine‐pyrimethamine plus amodiaquine on Day 1 and amodiaquine on both Day 2 and Day 3) is delivered to children aged 3–59 months in areas of highly season malaria transmission.
Sikai Huang, K. Scott Baker, Taiwo Ibinaiye, Olusola Oresanya, Chukwudi A Nnaji, Sol Richardson   +5 more
openalex   +2 more sources

Improved housing versus usual practice for additional protection against clinical malaria in The Gambia (RooPfs): a household-randomised controlled trial

The Lancet Planetary Health, 2021
Summary: Background: In malaria-endemic areas, residents of modern houses have less malaria than those living in traditional houses. We aimed to assess whether children in The Gambia received an incremental benefit from improved housing, where current ...
Margaret Pinder, PhD, John Bradley, PhD, Musa Jawara, MSc, Muna Affara, PhD, Lesong Conteh, PhD, Simon Correa, BSc, David Jeffries, PhD, Caroline Jones, PhD, Balla Kandeh, MSc, Jakob Knudsen, MAA, Yekini Olatunji, MBChB, Elisa Sicuri, PhD, Umberto D'Alessandro, ProfPhD, Steve W Lindsay, ProfPhD   +13 more
doaj   +1 more source

Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial. [PDF]

, 2015
OBJECTIVE: To investigate the effectiveness of seasonal malaria chemoprevention (SMC) and community case management with long-acting artemisinin-based combination therapies (ACTs) for the control of malaria in areas of extended seasonal malaria ...
Acheampong, Princess Ruhama, Antwi, Gifty Dufie, Bart Plange, Constance, Cairns, Matthew, Chandramohan, Daniel, Tagbor, Harry   +5 more
core   +1 more source

Seasonal malaria chemoprevention for malaria in children in areas with seasonal malaria

, 2022
This report was considered by the WHO/GMP Guideline Development Group on Malaria Chemoprevention for “Section 4.2.3 Seasonal malaria chemoprevention (SMC)” of the WHO Guidelines for malaria, 3 June 2022.
Thwing JI, Williamson J, Cavros I, Bhattarai A, Gutman J   +4 more
openaire   +1 more source