Results 41 to 50 of about 7,821 (219)

Review of intervention products for use in the prevention and control of anemia

open access: yesAnnals of the New York Academy of Sciences, Volume 1529, Issue 1, Page 42-60, November 2023., 2023
Abstract Anemia remains a major public health problem, especially in low‐ and middle‐income countries. The World Health Organization recommends several interventions to prevent and manage anemia in vulnerable population groups, including young children, menstruating adolescent girls and women, and pregnant and postpartum women.
Daniel Lopez de Romaña   +5 more
wiley   +1 more source

Effectiveness of malaria control programs in West Africa: a narrative review [PDF]

open access: yesInfectious Diseases and Tropical Medicine, 2022
Malaria is a major public health challenge in Africa, especially in West African countries. Its impacts on the individuals and families in these countries go beyond the physical health status to the financial crises it leaves them to nurse.
T. Sokunbi, T. Adesanya, F. Aremu
doaj   +1 more source

Spatial Optimization Methods for Malaria Risk Mapping in Sub‐Saharan African Cities Using Demographic and Health Surveys

open access: yesGeoHealth, Volume 7, Issue 10, October 2023., 2023
Abstract Vector‐borne diseases, such as malaria, are affected by the rapid urban growth and climate change in sub‐Saharan Africa (SSA). In this context, intra‐urban malaria risk maps act as a key decision‐making tool for targeting malaria control interventions, especially in resource‐limited settings.
Camille Morlighem   +7 more
wiley   +1 more source

Interplay among malnutrition, chemoprevention, and the risk of malaria in young Ugandan children: Longitudinal pharmacodynamic and growth analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 12, Issue 5, Page 656-667, May 2023., 2023
Abstract African children are at risk of malaria and malnutrition. We quantified relationships between malaria and malnutrition among young Ugandan children in a high malaria transmission region. Data were used from a randomized controlled trial where Ugandan HIV‐unexposed (n = 393) and HIV‐exposed (n = 186) children were randomized to receive no ...
Ali Mohamed Ali   +4 more
wiley   +1 more source

Cardiovascular concentration–effect relationships of amodiaquine and its metabolite desethylamodiaquine: Clinical and preclinical studies

open access: yesBritish Journal of Clinical Pharmacology, Volume 89, Issue 3, Page 1176-1186, March 2023., 2023
Aims Amodiaquine is a 4‐aminoquinoline used extensively for the treatment and prevention of malaria. Orally administered amodiaquine is largely converted to the active metabolite desethylamodiaquine. Amodiaquine can cause bradycardia, hypotension, and electrocardiograph QT interval prolongation, but the relationship of these changes to drug ...
Xin Hui S. Chan   +14 more
wiley   +1 more source

Cost-effectiveness of district-wide seasonal malaria chemoprevention when implemented through routine malaria control programme in Kita, Mali using fixed point distribution [PDF]

open access: yes, 2021
Background Seasonal malaria chemoprevention (SMC) is a strategy for malaria control recommended by the World Health Organization (WHO) since 2012 for Sahelian countries.
Cairns, Matt   +13 more
core   +3 more sources

Clinical and Biological Characteristics of Severe Malaria in Children under 5 Years Old in Benin

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2023, Issue 1, 2023., 2023
Background. Malaria is a global public health concern, mainly occurring in sub‐Saharan Africa. Children infected with malaria are more likely to develop severe disease, which can be fatal. During COVID‐19 in 2020, diagnosing and treating malaria became difficult. We analyzed the clinical characteristics and laboratory indicators of children with severe
Xiao Ma   +8 more
wiley   +1 more source

7H‐Pyrrolo[2,3‐d]pyrimidine‐4‐amines as Potential Inhibitors of Plasmodium falciparum Calcium‐Dependent Protein Kinases

open access: yesChemMedChem, Volume 17, Issue 22, November 18, 2022., 2022
Hitting malaria where it hurts: Pyrrolo[2,3‐d]pyrimidines have been designed as potential inhibitors targeting Plasmodium falciparum calcium‐dependent protein kinase 4 (PfCDPK4) using molecular modelling. Compounds displaying good binding interactions in silico were synthesised and assessed for inhibitory activity against PfCDPK4 and PfCDPK1, with ...
Tswene D. Seanego   +6 more
wiley   +1 more source

Effectiveness of Seasonal Malaria Chemoprevention in children under 10 years of age in Senegal: a stepped-wedge cluster-randomized trial [PDF]

open access: yes, 2016
This study was done to determine the effectiveness of Seasonal Malaria Chemoprevention in Senegalese children up to 10 years of age using a stepped-wedge design.
Milligan, Paul
core   +2 more sources

Near-term climate change impacts on sub-national malaria transmission [PDF]

open access: yes, 2021
The role of climate change on global malaria is often highlighted in World Health Organisation reports. We modelled a Zambian socio-environmental dataset from 2000 to 2016, against malaria trends and investigated the relationship of near-term ...
Bi, Yaxin   +4 more
core   +1 more source

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