Results 51 to 60 of about 3,567 (181)

Intermittent preventive treatment with dihydroartemisinin-piperaquine in Ugandan schoolchildren selects for Plasmodium falciparum transporter polymorphisms that modify drug sensitivity. [PDF]

, 2016
Dihydroartemisinin-piperaquine (DP) offers prolonged protection against malaria, but its impact on Plasmodium falciparum drug sensitivity is uncertain. In a trial of intermittent preventive treatment in schoolchildren in Tororo, Uganda, in 2011 to 2012 ...
Brooker, SJ, Conrad, MD, Dorsey, G, Kamya, MR, Legac, J, Nankabirwa, JI, Nsobya, SL, Rosenthal, PJ, Staedke, SG, Tukwasibwe, S, Tumwebaze, P, Wandera, B   +11 more
core   +3 more sources

Delivery strategies for malaria vaccination in areas with seasonal malaria transmission

BMJ Global Health, 2023
Background Seasonal vaccination with the RTS,S/AS01E malaria vaccine given alongside seasonal malaria chemoprevention (SMC) substantially reduces malaria in young children.
Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Jessica Myers   +9 more
doaj   +1 more source

Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia. [PDF]

, 2014
Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine-pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is characterized by the A581G Pfdhps mutation on a background of the double-mutant Pfdhps
Alifrangis, Michael, Cox, Jonathan, Dejene, Seyoum, Ishengoma, Deus, Kavishe, Reginald A, Lemnge, Martha M, Lusingu, John, Lynch, Caroline, Minja, Daniel TR, Nag, Sidsel, Ord, Rosalynn, Pearce, Richard, Pota, Hirva, Roper, Cally, Rwakimari, John, Schousboe, Mette L   +15 more
core   +3 more sources

Implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission: workshop meeting report

Malaria Journal, 2023
A workshop on implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission, was held as a hybrid meeting in Dakar, Senegal, and online, 23–25 January 2023. Delegates from
Corinne S. Merle, RTSS-SMC working group
doaj   +1 more source

School-aged children based seasonal malaria chemoprevention using artesunate-amodiaquine in Mali

Parasite Epidemiology and Control, 2018
Introduction: Malaria is still a public health problem in Africa. Seasonal Malaria Chemoprevention (SMC) is an efficient control strategy recommended by WHO that targets children under five year old living in areas of seasonal malaria transmission.
Mahamadou A. Thera, Abdoulaye K. Kone, Bourama Tangara, Elizabeth Diarra, Sirama Niare, Abdramane Dembele, Mahamadou S. Sissoko, Ogobara K. Doumbo   +7 more
doaj   +1 more source

Entomological impact of indoor residual spraying with pirimiphos-methyl: a pilot study in an area of low malaria transmission in Senegal. [PDF]

, 2018
BACKGROUND: Scaling-up of effective anti-malarial control strategies in Central-West region of Senegal has resulted in the sharp decline in malaria prevalence in this area.
Ba, Elhadji Conco Ciré, Cissé, Badara, Diallo, Abdoulaye, Diouf, Elhadji, Faye, Ousmane, Gaye, Oumar, Konaté, Lassana, Ndiaye, Magatte, Niang, El Hadji Amadou, Sy, Ousmane, Tairou, Fassiath   +10 more
core   +2 more sources

Impact of seasonal malaria chemoprevention on hospital admissions and mortality in children under 5 years of age in Ouelessebougou, Mali

Malaria Journal, 2020
Background Seasonal malaria chemoprevention is widely implemented in Sahel and sub-Sahel countries in Africa. Few studies have assessed the impact of the SMC on hospital admission and death when it is implemented in the health system.
Djibrilla Issiaka, Amadou Barry, Tiangoua Traore, Boubacar Diarra, David Cook, Mohamed Keita, Issaka Sagara, Patrick Duffy, Michal Fried, Alassane Dicko   +9 more
doaj   +1 more source

Molecular monitoring of Plasmodium falciparum super-resistance to sulfadoxine-pyrimethamine in Tanzania. [PDF]

, 2016
BACKGROUND: Sulfadoxine-pyrimethamine (SP) is recommended for prophylactic treatment of malaria in pregnancy while artemisinin combination therapy is the recommended first-line anti-malarial treatment.
Alifrangis, Michael, Ishengoma, Deus, Kaaya, Robert D, Kavishe, Adellaida A, Kavishe, Reginald A, Krogsgaard, Camilla, Nag, Sidsel, Notland, Jakob Ginsbak, Roper, Cally   +8 more
core   +4 more sources

Seasonal Malaria Chemoprevention Implementation: Effect on Malaria Incidence and Immunity in a Context of Expansion of P. falciparum Resistant Genotypes with Potential Reduction of the Effectiveness in Sub-Saharan Africa

Infection and Drug Resistance, 2022
Séni Nikiema,1,2 Issiaka Soulama,1,3 Salif Sombié,1 André-Marie Tchouatieu,4 Samuel Sindie Sermé,5 Noëlie Béré Henry,5 Nicolas Ouedraogo,1 Nathalie Ouaré,1,6 Raissa Ily,1,6 Oumarou Ouédraogo,3 Dramane Zongo,3 Florencia Wendkuuni Djigma,2 Alfred B Tiono,1
Nikiema S, Soulama I, Sombié S, Tchouatieu AM, Sermé SS, Henry NB, Ouedraogo N, Ouaré N, Ily R, Ouédraogo O, Zongo D, Djigma FW, Tiono AB, Sirima SB, Simporé J   +14 more
doaj  

Malaria in school-age children in Africa: an increasingly important challenge. [PDF]

, 2014
School-age children have attracted relatively little attention as a group in need of special measures to protect them against malaria. However, increasing success in lowering the level of malaria transmission in many previously highly endemic areas will ...
Brooker, Simon J, Clarke, Sian E, Fernando, Deepika, Gitonga, Caroline W, Greenwood, Brian, Nankabirwa, Joaniter, Schellenberg, David   +6 more
core   +2 more sources