Results 61 to 70 of about 1,896 (179)

Evaluation of direct and indirect effects of seasonal malaria chemoprevention in Mali [PDF]

Scientific Reports, 2018
AbstractRandomized controlled trials have established that seasonal malaria chemoprevention (SMC) in children is a promising strategy to reduce malaria transmission in Sahelian West Africa. This strategy was recently introduced in a dozen countries, and about 12 million children received SMC in 2016. However, evidence on SMC effectiveness under routine
Thomas Druetz, Thomas Druetz
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Seasonal Malaria Chemoprevention in Guinea in 2020: coverage survey results [PDF]

, 2021
In 2020 SMC was implemented in 17 out of 33 prefectures, which include 50% of the population outside the city of Conakry. The COVID-19 pandemic, and the presidential elections in Guinea, could potentially have affected SMC campaigns in 2020, it was therefore important to evaluate coverage of SMC given these challenges and the increased area of ...
Loua, Kovana Marcel, Milligan, Paul
openaire   +2 more sources

Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of resurgence: a modelling study

BMC Infectious Diseases, 2019
Background The only licensed malaria vaccine, RTS,S/AS01, has been developed for morbidity-control in young children. The potential impact on transmission of deploying such anti-infective vaccines to wider age ranges, possibly with co-administration of ...
Flavia Camponovo, Chris F. Ockenhouse, Cynthia Lee, Melissa A. Penny   +3 more
doaj   +1 more source

Delivery strategies for malaria vaccination in areas with seasonal malaria transmission

BMJ Global Health, 2023
Background Seasonal vaccination with the RTS,S/AS01E malaria vaccine given alongside seasonal malaria chemoprevention (SMC) substantially reduces malaria in young children.
Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Jessica Myers   +9 more
doaj   +1 more source

Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation [PDF]

The Journal of Infectious Diseases, 2019
Abstract Background Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory ...
Patrick E. Duffy, Sekouba Keita, Jennifer Kwan, Adama B. Dembele, Oumar Attaher, Almahamoudou Mahamar, Alassane Dicko, Mamoudou B Samassekou, Michal Fried, Barou Coulibaly, Sibiri Sissoko, Moussa B. Kanoute, Bacary S. Diarra, Djibrilla Issiaka, Amadou Barry, Kadidia B. Cisse, Kalifa Diarra, Tiangoua Traore, Irfan Zaidi   +18 more
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Implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission: workshop meeting report

Malaria Journal, 2023
A workshop on implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission, was held as a hybrid meeting in Dakar, Senegal, and online, 23–25 January 2023. Delegates from
Corinne S. Merle, RTSS-SMC working group
doaj   +1 more source

Sub-national tailoring of seasonal malaria chemoprevention in Mali based on malaria surveillance and rainfall data

Parasites & Vectors, 2022
Abstract Background In malaria endemic countries, seasonal malaria chemoprevention (SMC) interventions are performed during the high malaria transmission in accordance with epidemiological surveillance data. In this study we propose a predictive approach for tailoring the timing and number of cycles of SMC in all health ...
Cissoko, Mady, Sagara, Issaka, Landier, Jordi, Guindo, Abdoulaye, Sanogo, Vincent, Coulibaly, Oumou, Dembélé, Pascal, Dieng, Sokhna, Bationo, Cedric, Diarra, Issa, Magassa, Mahamadou, Berthé, Ibrahima, Katilé, Abdoulaye, Traoré, Diahara, Dessay, Nadine, Gaudart, Jean   +15 more
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A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research, 2023
Background The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) for children aged 3 to 59 months, living in areas where malaria transmission is highly seasonal ...
Craig Bonnington, Sol Richardson, Godfrey Magumba, Christian Rassi, Jane Nabakooza, Denis Rubahika, Anthony Nuwa, James Tibenderana, Jimmy Opigo, Jane Achan, Richard Kajubi, Kevin Baker, Jennifer Ainsworth   +12 more
doaj  

Impact of seasonal malaria chemoprevention on hospital admissions and mortality in children under 5 years of age in Ouelessebougou, Mali

Malaria Journal, 2020
Background Seasonal malaria chemoprevention is widely implemented in Sahel and sub-Sahel countries in Africa. Few studies have assessed the impact of the SMC on hospital admission and death when it is implemented in the health system.
Djibrilla Issiaka, Amadou Barry, Tiangoua Traore, Boubacar Diarra, David Cook, Mohamed Keita, Issaka Sagara, Patrick Duffy, Michal Fried, Alassane Dicko   +9 more
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Effectiveness of seasonal malaria chemoprevention at scale in west and central Africa: an observational study [PDF]

The Lancet, 2020
Seasonal malaria chemoprevention (SMC) aims to prevent malaria in children during the high malaria transmission season. The Achieving Catalytic Expansion of SMC in the Sahel (ACCESS-SMC) project sought to remove barriers to the scale-up of SMC in seven countries in 2015 and 2016.
Jean-Bosco Ouédraogo, Mamadou Chérif Traore, Timothee Guilavogui, Matt Coldiron, Godwin Ntadom, Adama Sanogo, Patrice Coulibaly, Halimatou Alassana Messan, Yolanda Fernandez, Bala Audu, Sham Lal, Hamit Kesseley, Julian Muwanguzi, Musa Abubakar Kana, Nadine Ngarnaye, Markieu Janneh Kaira, Harriet Kivumbi, Joanna Stenstrom Johansson, Ebenezer Baba, Balla Kandeh, Kodbesse Boulotigam, Maddy Marasciulo, Eugene Kaman Lama, Raoul Mansukhani, Kolawole Maxwell, Suzanne Van Hulle, Sonny Johnbull Ogboi, Jane Achan, David Collins, Eric Hubbard, Mariama Sire Sano, Fatou Jah, Shanthi N. Pal, Ibrahim Laminou, Serign J. Ceesay, Khalid B. Beshir, Abdoulaye Djimde, Arantxa Roca-Feltrer, Paul Milligan, André-Marie Tchouatieu, Prudence Hamade, Diakalidia Kone, Noha Iessa, Christine M Halleux, Issaka Zongo, Paul Snell, Kovana Marcel Loua, Alassane Dicko, Issaka Sagara, Yacouba Savodogo, Yacine Djibo, Moussa Keita, Rhosyn Tuta, Gladys Tetteh, Daugla Doumagoum, Djiddi Ali Sougoudi, Susana Scott, Matthew Cairns, Hadiza Jackou, Corinne Merle, Momodou Kalleh, James K Tibenderana, Fara Ndiaye, Alice Kiba, Colin J. Sutherland, Aishatu Yinusa Cassandra Elagbaje, George Jagoe, Colin Gilmartin, Houda Sefiani, Tony Eloike, Jean Louis NdDiaye, Ibrahim Ouba, Rahila Abdoulaye, Diego Moroso, Rachida Souleymani, Abdoulaye Hama Diallo, Huja Jah, Emile Ouedraogo, Rebecca F. Grais, Kalifa Bojang, Lantorina Razafindralambo   +80 more
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