Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly+14 more
doaj +1 more source
Seasonal use case for the RTS,S/AS01 malaria vaccine: a mathematical modelling study [PDF]
BACKGROUND: A 2021 clinical trial of seasonal RTS,S/AS01E (RTS,S) vaccination showed that vaccination was non-inferior to seasonal malaria chemoprevention (SMC) in preventing clinical malaria.
Cairns, M+12 more
core +3 more sources
Facilitators and barriers to seasonal malaria chemoprevention (SMC) uptake in Nigeria: a qualitative approach. [PDF]
Abstract Background SMC was adopted in Nigeria in 2014 and by 2021 was being implemented in 18 states, over four months between June and October by 143000 community drug distributors (CDDs) to a target population of 23million children.
Ogbulafor N+16 more
europepmc +4 more sources
Model-informed target product profiles of long-acting-injectables for use as seasonal malaria prevention [PDF]
Seasonal malaria chemoprevention (SMC) has proven highly efficacious in reducing malaria incidence. However, the continued success of SMC is threatened by the spread of resistance against one of its main preventive ingredients, Sulfadoxine-Pyrimethamine (
Burgert, L.+4 more
core +1 more source
Impact of seasonal malaria chemoprevention on prevalence of malaria infection in malaria indicator surveys in Burkina Faso and Nigeria [PDF]
BackgroundIn 2012, the WHO issued a policy recommendation for the use of seasonal malaria chemoprevention (SMC) to children 3–59 months in areas of highly seasonal malaria transmission. Clinical trials have found SMC to prevent around 75% of clinical malaria.
Monica Anna de Cola+12 more
openaire +5 more sources
The use of video job-aids to improve the quality of seasonal malaria chemoprevention delivery. [PDF]
Mobile phones are increasingly used in community health programmes, but the use of video job-aids that can be displayed on smart phones has not been widely exploited. We investigated the use of video job-aids to support the delivery of seasonal malaria chemoprevention (SMC) in countries in West and Central Africa. The study was prompted by the need for
Scott S+36 more
europepmc +5 more sources
Modeling sustained transmission of Wolbachia among Anopheles mosquitoes: Implications for malaria control in Haiti [PDF]
Wolbachia infection in Anopheles albimanus mosquitoes can render mosquitoes less capable of spreading malaria. We develop and analyze an ordinary differential equation model to evaluate the effectiveness of Wolbachia-based vector control strategies among wild Anopheles mosquitoes in Haiti. The model tracks the mosquito life stages, including egg, larva,
arxiv +1 more source
Evaluation of seasonal malaria chemoprevention in two areas of intense seasonal malaria transmission: Secondary analysis of a household-randomised, placebo-controlled trial in Houndé District, Burkina Faso and Bougouni District, Mali. [PDF]
BACKGROUND: Seasonal malaria chemoprevention (SMC) is now widely deployed in the Sahel, including several countries that are major contributors to the global burden of malaria.
Barry, Amadou+17 more
core +2 more sources
Seasonal Malaria Chemoprevention Coverage in Guinea in 2019 [PDF]
SMC involves the administration of a treatment course of sulfadoxine-pyrimethamine plus amodiaquine once a month to children aged 3 59 months during the high risk period each year to prevent malaria. SMC over 4 months of the year was introduced in Guinea in 2015 in 6 prefectures, scaling up to 13 prefectures by 2018.
Loua, Kovana Marcel, Milligan, Paul
openaire +2 more sources