Results 41 to 50 of about 3,433 (163)

Evaluation of protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside against mercuric chloride-induced nephrotoxicity in rats

, 2019
The toxicity of heavy metals such as mercury (Hg) in humans and animals is well documented. The kidney is the primary deposition site of inorganic-Hg and target organ of its toxicity.
Javaraiah, R, Aqeel, T, Chikkalakshmipura Gurumallu, S, AlQurashi, N, Hashimi, SM   +4 more
core   +1 more source

Protective role of flaxseed lignan secoisolariciresinol diglucoside against lead-acetate-induced oxidative-stress-mediated nephrotoxicity in rats

, 2021
Background: Lead (Pb) is a toxic heavy metal that causes kidney injury and oxidative tissue damage. Current drugs to treat nephrotoxicity have multiple side-effects. Therefore, the development of novel therapeutic approaches is urgently required. Purpose:
Javaraiah, R, Gurumallu, SC, Aqeel, T, Lohith, NC, Rajesh Javaraiah, Bhaskar, A, Sunil Chikkalakshmipura Gurumallu, Saeed Mujahid Hashimi, Nisha Chiriapanda Lohith, Hashimi, SM, Ashwini Bhaskar, Tareq Aqeel   +11 more
core   +1 more source

The Pisum sativum SAD short-chain dehydrogenase/reductase: quinone reduction, tissue distribution, and heterologous expression [PDF]

, 2011
The pea (Pisum sativum) tetrameric short-chain alcohol dehydrogenase-like protein (SAD) family consists of at least three highly similar members (SAD-A, -B, and -C).
Hilja Strid, Strid, Hilja, Eriksson, Leif A.,, Nikolai Scherbak, Åke Strid, Strid, Hilja,, Anneli Ala-Häivälä, Böwer, Nathalie, Strid, Åke, Grahn, Elin M., Brosché, Mikael, Ala-Häivälä, Anneli, Gittins, John R.,, Elin Grahn, Mikael Brosché, John R. Gittins, Strid, Åke,, Grahn, Elin, Nathalie Böwer, Gittins, John R., Scherbak, Nikolai,, Eriksson, Leif A., Leif A. Eriksson, Grahn, Elin M.,, Scherbak, Nikolai, Brosché, Mikael,   +25 more
core   +1 more source

Micropropagation and Production of Health Promoting Lignans in Linum usitatissimum

Plants, 2020
Linum usitatissimum commonly known as flax or linseed is an important medicinal plant, produces medicinally potent lignans, used in the treatment of several human diseases.
Irfan Khan, Mubarak Ali Khan, Muhammad Amir Shehzad, Amir Ali, Sher Mohammad, Huma Ali, Mohammed Nasser Alyemeni, Parvaiz Ahmad   +7 more
doaj   +1 more source

Secoisolariciresinol diglucoside regulates estrogen receptor expression to ameliorate OVX-induced osteoporosis

Journal of Orthopaedic Surgery and Research, 2023
Objective Secoisolariciresinol diglucoside (SDG) is a phytoestrogen that has been reported to improve postmenopausal osteoporosis (PMOP) caused by estrogen deficiency.
Guofang Chen, Yansong Chen, Junyi Hong, Junwei Gao, Zhikun Xu   +4 more
doaj   +1 more source

Lignan‐rich Norway spruce (Picea abies) resin extract exhibits anti‐inflammatory, skin‐regenerative and anti‐acne effects: In vitro, in silico, biocompatibility and exploratory clinical findings

International Journal of Cosmetic Science, EarlyView.
GA text A 30% Picea abies resin extract cream combined antimicrobial, anti‐inflammatory and early pro‐repair activities relevant to acne‐prone skin. The formulation showed strong activity against Cutibacterium acnes, reduced inflammatory cytokines and demonstrated promising tolerability and efficacy in an exploratory in‐use study. Abstract Objective To
Simone Parrotta, Kamilla Yamileva, Laura Punakallio, Maryam Ghanbarirad, Evgen Multia   +4 more
wiley   +1 more source

Therapeutic Efficacy of a Formulation Prepared with Linum usitatissimum L., Plantago ovata Forssk., and Honey on Uncomplicated Pelvic Inflammatory Disease Analyzed with Machine Learning Techniques

Pharmaceutics, 2023
A single-blind double-dummy randomized study was conducted in diagnosed patients (n = 66) to compare the efficacy of Linseeds (Linum usitatissimum L.), Psyllium (Plantago ovata Forssk.), and honey in uncomplicated pelvic inflammatory disease (uPID) with ...
Sana Qayyum, Arshiya Sultana, Md Belal Bin Heyat, Khaleequr Rahman, Faijan Akhtar, Amin ul Haq, Batool Abdulelah Alkhamis, Mohammed Aedh Alqahtani, Reem M. Gahtani   +8 more
doaj   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Formation of Lignans(-)-Secoisolariciresinol and (-)-Matairesinol with Forsythia intermedia Cell-Free Extracts [PDF]

, 1991
In vivo labeling experiments of Forsythia intermedia plant tissue with [8-(C-14)]- and [9,9-(2)H2,OC(2)H3]coniferyl alcohols revealed that the lignans, (-)-secoisolariciresinol and (-)-matairesinol, were derived from two coniferyl alcohol molecules; no ...
Lewis, Norman G., Umezawa, Toshiaki, Davin, Laurence B.   +2 more
core  

Secoisolariciresinol Diglucoside Improves Ovarian Reserve in Aging Mouse by Inhibiting Oxidative Stress

Frontiers in Molecular Biosciences, 2022
Ovarian reserve is a key factor in the reproductive function of the ovaries. Ovarian aging is characterized by a gradual decline in the quantity and quality of follicles.
XueLai He, Yong Wang, MeiQi Wu, JiangChun Wei, XianDuo Sun, AnHua Wang, GaoSheng Hu, JingMing Jia   +7 more
doaj   +1 more source