Results 51 to 60 of about 3,433 (163)

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid, Maria Maqsood, Nimrah Ashraf, Farzeen Asghar, Nauman Khalid   +4 more
wiley   +1 more source

Determination of secoisolariciresinol diglucoside by high performance liquid chromatography

浙江大学学报. 农业与生命科学版, 2008
High performance liquid chromatography-photodiode array detection-elctrospray ionizationmass spectrometry (HPLC-PAD-ESI-MS) method was used to determine secoisolariciresinol diglucoside (SDG) qualitatively and quantitatively. Precision, stability, limits
ZHANG Wen-bin, XU Shi-ying, WANG Zhang, YANG Rui-jin, LU Rong-rong   +4 more
doaj   +1 more source

Linagliptin and secoisolariciresinol diglucoside attenuate hyperlipidemia and cardiac hypertrophy induced by a high-methionine diet in rats via suppression of hyperhomocysteinemia-induced endoplasmic reticulum stress

Frontiers in Pharmacology, 2023
Background: Cardiac hypertrophy (CH) is one of the contributing causes of morbidity and mortality. Hyperhomocysteinemia (HHcy) is one of the diseases which may predispose hyperlipidemia and CH. Linagliptin (Lina) and secoisolariciresinol diglucoside (SDG)
Israa A. Jalal, Abeer Elkhoely, Shimaa K. Mohamed, Amany A. E. Ahmed   +3 more
doaj   +1 more source

Anti‐Aging Potential of Callus Culture: Mechanisms, Efficacy and Future Trends

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Callus culture technology revolutionizes skin antiaging research, offering a sustainable and efficient method for producing bioactive compounds with potent geroprotective properties. This plant tissue and cell culture technique enables the controlled biosynthesis of beneficial phytochemicals while mitigating the variability and ...
Amir Mohammad Sharafi, Ali Khajeei, Maryam Hasan Zadeh Navroodi, Soheila Mokari, Seydeh Halimeh Najafi, Mohaddeseh Argha, Faezeh Talaei Shahmirzadi, Parina Asgharian, Tooba Gholikhani   +8 more
wiley   +1 more source

Characterization of Klebsiella sp strain S1: a bacterial producer of secoisolariciresinol through biotransformation [PDF]

, 2016
Secoisolariciresinol (SECO) is a lignan of potential therapeutic value for diseases such as cancer, but its use has been limited by the lack of ideal production methods, even though its precursors are abundant in plants, such as flaxseeds.
Zhu, Songling, Zhao, Dan-Dan, Zhou, Yu-Jie, Li, Jia-Jing, Yang, Dong-Hui, Liu, Shu-Lin   +5 more
core   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, Volume 117, Issue 8, Page 2064-2084, August 2026.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Crystal and Molecular Structure of Secoisolariciresinol [PDF]

, 1999
The R,R-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butandiol lignan secoisolariciresinol (1) is a constituent of Gymnosperms used in the treatment of benign prostatic hyperplasya.
Kulshrestha, Manish, Chattopadhyay, Sunil K., Viterbo, Davide, Davide Viterbo, Sunil K. Chattopadhyay, Appendino, Giovanni, Marco Milanesio, Milanesio, Marco, Giovanni Appendino, Manish Kulshrestha   +9 more
core   +1 more source

MODIFICATION OF LIGNANS BY TRAMETES HIRSUTA LACCASE

BioResources, 2009
Oxidative polymerization of two isolated lignans, secoisolariciresinol, and secoisolariciresinol diglucoside, as well as the lignan macromolecule, by a high redox potential Trametes hirsuta laccase was studied with different analytical methods.
Maija-Liisa Mattinen, Karin Struijs, Tapani Suortti, Ismo Mattila, Kristiina Kruus, Stefan Willför, Tarja Tamminen, Jean-Paul Vincken   +7 more
doaj  

The Effect of Active Ingredient of Safflower on The Bacterial Inhibition in Croissants and Studying Its Sensory Properties [PDF]

Tikrit Journal for Agricultural Sciences
This study examined the effects of hydrothermal extraction and filter paper purification on the active phenolic components of dried safflower (Carthamus tinctorius L.). Subsequently, the solvent was evaporated using a Bochi Mrs. B-200 spray dryer.
EshraQ.Gehad Khudair, Bahira M. Al-Timim, Sanaa A. Al Sahib   +2 more
doaj   +1 more source

The legitimacy of using dietary supplement diglycoside secoisolariciresinol (SDG) from flaxseed in cancer

Roczniki Panstwowego Zakladu Higieny, 2021
Linseed, commonly known as flaxseed, is a fibre-rich food product. According to the recent study prepared by the American Institute for Cancer Research (AICR), an adequate intake of dietary fiber contributes to reducing the risk of colorectal cancer.
Karolina Dobrowolska, Bożena Regulska-Ilow   +1 more
doaj   +1 more source