Results 101 to 110 of about 2,867 (139)

Secoisolariciresinol diglucoside attenuates cardiac hypertrophy and oxidative stress in monocrotaline-induced right heart dysfunction

, 2017
Pulmonary arterial hypertension (PAH) occurs when remodeling of pulmonary vessels leads to increased pulmonary vascular resistance resulting in increased pulmonary arterial pressure.
Bonetto, Jéssica Hellen Poletto, Seolin, Bruna Gazzi de Lima, Fernandes, Rafael Oliveira, Turck, Patrick, Belló-Klein, Adriane, Araújo, Alex Sander da Rosa, Puukila, Stephanie, Carraro, Cristina Campos, Boreham, Douglas, Khaper, Neelam   +9 more
core   +1 more source

Randomized Phase IIB Trial of the Lignan Secoisolariciresinol Diglucoside in Premenopausal Women at Increased Risk for Development of Breast Cancer. [PDF]

Cancer Prev Res (Phila), 2020
Fabian CJ, Khan SA, Garber JE, Dooley WC, Yee LD, Klemp JR, Nydegger JL, Powers KR, Kreutzjans AL, Zalles CM, Metheny T, Phillips TA, Hu J, Koestler DC, Chalise P, Yellapu NK, Jernigan C, Petroff BK, Hursting SD, Kimler BF.   +19 more
europepmc   +1 more source

Secoisolariciresinol Diglucoside Delays the Progression of Aging-Related Diseases and Extends the Lifespan of Caenorhabditis elegans via DAF-16 and HSF-1. [PDF]

Oxid Med Cell Longev, 2020
Lu M, Tan L, Zhou XG, Yang ZL, Zhu Q, Chen JN, Luo HR, Wu GS.   +7 more
europepmc   +1 more source

Secoisolariciresinol Diglucoside Exerts Anti-Inflammatory and Antiapoptotic Effects through Inhibiting the Akt/IκB/NF-κB Pathway on Human Umbilical Vein Endothelial Cells. [PDF]

Mediators Inflamm, 2020
Zhang S, Cheng M, Wang Z, Liu Y, Ren Y, Rong S, Wang X.   +6 more
europepmc   +1 more source

Availability of dietary secoisolariciresinol diglucoside on borderline blood cholesterol level in men: a randomized, parallel, controlled, double-blinded clinical trial. [PDF]

J Clin Biochem Nutr
Ookoshi K, Sawane K, Fukumitsu S, Aida K.   +3 more
europepmc   +1 more source

[Dietary secoisolariciresinol diglucoside alleviates chronic kidney disease in offspring rats caused by maternal trans-fatty acid exposure by regulating the Bcl-2/Bax/caspase-3 signaling axis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Ma S, Chen M, Wu T, Zhao W.
europepmc   +1 more source

Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits Libby amphibole fiber-induced acute inflammation in mice. [PDF]

Toxicol Appl Pharmacol, 2019
Christofidou-Solomidou M, Pietrofesa RA, Park K, Albelda SM, Serve KM, Keil DE, Pfau JC.   +6 more
europepmc   +1 more source

Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells. [PDF]

Biochim Biophys Acta Gen Subj, 2018
Mishra OP, Popov AV, Pietrofesa RA, Nakamaru-Ogiso E, Andrake M, Christofidou-Solomidou M.   +5 more
europepmc   +1 more source

Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy. [PDF]

J Mol Cell Cardiol, 2019
Kokkinaki D, Hoffman M, Kalliora C, Kyriazis ID, Maning J, Lucchese AM, Shanmughapriya S, Tomar D, Park JY, Wang H, Yang XF, Madesh M, Lymperopoulos A, Koch WJ, Christofidou-Solomidou M, Drosatos K.   +15 more
europepmc   +1 more source

The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth. [PDF]

Breast Cancer Res Treat, 2019
Bowers LW, Lineberger CG, Ford NA, Rossi EL, Punjala A, Camp KK, Kimler BK, Fabian CJ, Hursting SD.   +8 more
europepmc   +1 more source