Flaxseed is a rich source of α-linolenic acid and phytoestrogens, mainly lignans, whose metabolites (enterodiol and enterolactone) can affect estrogen functions.
S. Mattioli +6 more
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International audienceINTRODUCTION: In the plant kingdom, flaxseed (Linum usitatissimum L.) is the richest source of secoisolariciresinol diglucoside (SDG), which is of great interest because of its potential health benefits for human beings.
Tatsis, E. +12 more
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Phase I and II enzyme induction and inhibition by secoisolariciresinol diglucoside and it's aglycone [PDF]
The flaxseed lignan, secoisolariciresinol diglucoside (SDG), and its aglycone, secoisolariciresinol (SECO), have demonstrated benefits in the treatment and/or prevention of cancer, diabetes and cardiovascular disease. In order for the lignans to be used
Boyd, Erin Margaret Rose
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A Mini Review on Components of Flax Seed and Their Effects on Breast Cancer
Breast cancer is recognized as one of the most common cancers worldwide that can lead to death. Alternative treatment options are needed due to drug resistance caused by current treatment methods such as chemotherapy, inclusion of healthy cells in the ...
Senem Akkoç, İrem Bayar
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Microwave-assisted extraction (MAE) of Secoisolariciresinol Diglucoside (SDG) from flaxseed
Secoisolariciresinol diglucoside (SDG) is the main lignan from flaxseed, and it is the main exogenous precursor of the mammalian lignans enterolactone and enterodiol. SDG is a recognised nutraceutical which presents several health benefits; it has strong
Nemes, Simona
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Aim. Animal and human study evidence supports the hypothesis that flaxseed lignan complex (FLC) at a dose of 600 mg secoisolariciresinol diglucoside (SDG)/day for three months would combat hyperglycaemia, dyslipidemia, blood pressure, central obesity ...
D. E. Barre +6 more
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High concentrations of enterolignans in plasma are associated with a lower risk of acute coronary events. However, little is known about the absorption and excretion of enterolignans. The pharmacokinetic parameters and urinary excretion of enterodiol and
Arts, I.C.W. +3 more
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Cookies enriched with anethole and secoisolariciresinol diglucoside from flaxseed and fennel seeds improve hypercholesterolemia, lipid profile, and liver functions: A pilot study. [PDF]
Noreen S +5 more
europepmc +1 more source
Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells. [PDF]
Pietrofesa RA +5 more
europepmc +1 more source
Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605). [PDF]
Pietrofesa RA +11 more
europepmc +1 more source

