Results 71 to 80 of about 2,867 (139)

Neurobiological Synergy of Plant and Animal Sources of Omega‐3 and Exercise in Aging: Implications for Molecular Signaling, Memory, Spatial Learning, and Brain Function

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
Omega‐3 fatty acids from animal sources, combined with exercise, modulate key molecular pathways to enhance neurogenesis, synaptic plasticity, and antioxidant defenses. These interventions also increase tissue plasminogen activator activity, promoting both amyloid‐β degradation and proBDNF cleavage into BDNF, thereby reducing neurodegeneration and ...
Yikuang Hao, Sima‐sadat Sabihi
wiley   +1 more source

Antioxidant Activity of Flaxseed Extracts in Lipid Systems

Molecules, 2015
The aim of this work was to compare the antioxidant activity of the extract of flaxseed and its alkaline hydrolysate in two model systems: lipid autoxidation of triacylglycerols of sunflower oil (TGSO)—in a homogeneous lipid media and during β-carotene ...
Adriana Slavova-Kazakova, Magdalena Karamać, Vessela Kancheva, Ryszard Amarowicz   +3 more
doaj   +1 more source

Fingerprinting of Semi‐Refined Flaxseed Protein Using Raman Spectroscopy and Multivariate Analysis: Pulsed Electric Field (PEF)‐Assisted Alkali and Aqueous Extraction Methods Alter Composition and Protein Conformation

Journal of Raman Spectroscopy, Volume 56, Issue 9, Page 788-800, September 2025.
Structural changes in semi‐refined flaxseed protein extracts were effectively characterized using Raman spectroscopy coupled with PCA. The application of higher PEF energy enhanced hydrophobic interactions among aliphatic amino acids, while at lower PEF inputs, the extraction medium dictated secondary structure formation: α‐helices favored in aqueous ...
Jervee M. Punzalan, Peter Hartono, Sara J. Fraser‐Miller, Sze Ying Leong, Kevin Sutton, Gert‐Jan Moggre, Indrawati Oey, Keith C. Gordon   +7 more
wiley   +1 more source

Ruminal Prevotella spp. may play an important role in the conversion of plant lignans into human health beneficial antioxidants.

PLoS ONE, 2014
Secoisolariciresinol diglucoside (SDG), the most abundant lignan in flaxseed, is metabolized by the ruminal microbiota into enterolignans, which are strong antioxidants.
Ana L B Schogor, Sharon A Huws, Geraldo T D Santos, Nigel D Scollan, Barbara D Hauck, Ana L Winters, Eun J Kim, Hélène V Petit   +7 more
doaj   +1 more source

The estrobolome: Estrogen‐metabolizing pathways of the gut microbiome and their relation to breast cancer

International Journal of Cancer, Volume 157, Issue 4, Page 599-613, 15 August 2025.
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder, Amee R. Manges, Rachel A. Murphy   +2 more
wiley   +1 more source

Flaxseed lignan secoisolariciresinol diglucoside improves insulin sensitivity through upregulation of GLUT4 expression in diet-induced obese mice

, 2015
The efficacy and mechanism of flaxseed lignan secoisolariciresinol diglucoside (SDG) on glucose hemostasis in obese mice were examined. Male C57BL/6J mice fed on a high-fat diet (60 kcal% fat) for 15 weeks were divided into four groups and treated by ...
Ghose, Kaushik, Roy, Moumita, Wang, Yanwen, Fofana, Bourlaye, Nair, Sandhya, Nixon, Marva-Sweeney, Yao, Xing-Hai, Nyomba, Gregoire B. L.   +7 more
core   +1 more source

The Phenolic Signature of Psidium cattleianum Fruits and Leaves Modulates TRPV1 and TRPA1 Transient Receptor Potential Channels: A Metabolomics, In Vitro, and In Silico Study

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
An untargeted metabolomics study was performed to find the encompassed phytochemicals in the fruit and leaf extract of Psidium cattleianum. This enabled the annotation of 469 compounds belonging to different phenolic subclasses, with a predominance of flavonoids and phenolics.
Leilei Zhang, Fabio Arturo Iannotti, Fatema R. Saber, Reem K. Arafa, Aniello Schiano Moriello, Rasha A. Rasle, Anton Soria‐Lopez, Sara G. Abd EL‐Gawwad, Gabriele Rocchetti, Paz Otero, Łukasz Kulinowski, Krystyna Skalicka‐Woźniak, Luigi Lucini, Jesus Simal‐Gandara   +13 more
wiley   +1 more source

Flax lignans regulate the conversion of α-linolenic acid into n-3 LCPUFAs in mice ingesting sunflower phospholipid-stabilized nanoemulsions

Food Science and Human Wellness
Dietary supplementation with plant-derived α-linolenic acid (ALA) has the potential to alleviate the insufficient intake of global n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFAs), but faces the bottleneck of high β-oxidation consumption ...
Lei Wang, Xiao Yu, Chen Cheng, Jiqu Xu, Xia Xiang, Xiaoqiao Tang, Qianchun Deng   +6 more
doaj   +1 more source

Revealing the Mammalian Lignan Precursor Secoisolariciresinol Diglucoside in Flaxseed by Ionspray Mass Spectrometry

, 1994
Ionspray mass spectrometry allowed the rapid detection and unambiguous identification of secoisolariciresinol diglucoside, an important mammalian lignan precursor occurring in flax seed.
Valerio Giannellini, Massimo BambagiottiAlberti, Silvia A Coran, Caterina Ghiara, Andrea Raffaelli   +4 more
core  

Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside [PDF]

, 2010
Our previous study demonstrated that lignan metabolites enterolactone and enterodiol inhibited colonic cancer cell growth by inducing cell cycle arrest and apoptosis.
Ayella, Allan, Tomich, John M., Iwamoto, Takeo, Wang, Weiqun, Lim, Soyoung, Lin, Dingbo, Jiang, Yu   +6 more
core